Results 41 to 50 of about 4,929,681 (330)
Стратегические решения и риск-менеджмент, 2022 The article substantiates the need for a radical review of approaches to the training of managers in high technological industries, whose professional activity context is defined by continuous crises, growing uncertainty, dynamic trends, the massive ...
L. D. Gitelman +3 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Engineering Crowdsourced Stream Processing Systems [PDF]
, 2014 A crowdsourced stream processing system (CSP) is a system that incorporates crowdsourced tasks in the processing of a data stream. This can be seen as enabling crowdsourcing work to be applied on a sample of large-scale data at high speed, or ...
Carlos Castillo +4 more
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Sensors, 2021 In this paper, we present an exhaustive description of an extensible e-Health Internet-connected embedded system, which allows the measurement of three biometric parameters: pulse rate, oxygen saturation and temperature, via several wired and wireless ...
Cristian Vizitiu +4 more
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Software and Systems ModelingThe perception of the value and propriety of modern engineered systems is changing. In addition to their functional and extra-functional properties, nowadays' systems are also evaluated by their sustainability properties. The next generation of systems will be characterized by an overall elevated sustainability -- including their post-life, driven by ...
Istvan David, Dominik Bork, Gerti Kappel
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Enhancing Strategic Planning of Projects: Selecting the Right Product Development Methodology
Information, 2023 The selection of an appropriate development methodology is a critical strategic decision when managing a New Product Development (NPD) project. However, accurately estimating project duration based on the chosen methodology remains a challenge.
Itai Lishner, Avraham Shtub
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On Reverse Engineering in the Cognitive and Brain Sciences [PDF]
, 2012 Various research initiatives try to utilize the operational principles of organisms and brains to develop alternative, biologically inspired computing paradigms and artificial cognitive systems.
Schierwagen, Andreas
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An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source