Results 41 to 50 of about 28,722,346 (323)

Tutorial for Using Control Systems Engineering to Optimize Adaptive Mobile Health Interventions

Journal of Medical Internet Research, 2018
Background Adaptive behavioral interventions are individualized interventions that vary support based on a person's evolving needs. Digital technologies enable these adaptive interventions to function at scale.
E. Hekler, D. Rivera, César A. Martín, Sayali S. Phatak, Mohammad T. Freigoun, E. Korinek, P. Klasnja, M. Adams, M. Buman   +8 more
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Multi-agent systems for power engineering applications - part 1 : Concepts, approaches and technical challenges [PDF]

, 2007
This is the first part of a 2-part paper that has arisen from the work of the IEEE Power Engineering Society's Multi-Agent Systems (MAS) Working Group. Part 1 of the paper examines the potential value of MAS technology to the power industry.
Catterson, V.M., Davidson, E.M., Dimeas, A.L., Funabashi, T., Hatziargyriou, N.D., McArthur, S.D.J., Ponci, F.   +6 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Exhaustive Description of the System Architecture and Prototype Implementation of an IoT-Based eHealth Biometric Monitoring System for Elders in Independent Living

Sensors, 2021
In this paper, we present an exhaustive description of an extensible e-Health Internet-connected embedded system, which allows the measurement of three biometric parameters: pulse rate, oxygen saturation and temperature, via several wired and wireless ...
Cristian Vizitiu, Călin Bîră, Adrian Dinculescu, Alexandru Nistorescu, Mihaela Marin   +4 more
doaj   +1 more source

Transdisciplinary systems engineering: implications, challenges and research agenda

International Journal of Agile Systems and Management, 2019
Transdisciplinary processes have been the subject of research since several decades already. Transdisciplinary processes are aimed at solving ill-defined and socially relevant problems.
N. Wognum, C. Bil, F. Elgh, M. Peruzzini, J. Stjepandić, W. Verhagen   +5 more
semanticscholar   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Enhancing Strategic Planning of Projects: Selecting the Right Product Development Methodology

Information, 2023
The selection of an appropriate development methodology is a critical strategic decision when managing a New Product Development (NPD) project. However, accurately estimating project duration based on the chosen methodology remains a challenge.
Itai Lishner, Avraham Shtub
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Software Architecture Modeling of AUTOSAR-Based Multi-Core Mixed-Critical Electric Powertrain Controller

Modelling, 2021
In this paper, we present a transition journey of automotive software architecture design from using legacy approaches and toolchains to employing new modeling capabilities in the recent releases of Matlab/Simulink (M/S). We present the seamless approach
Sakthivel Manikandan Sundharam, Padma Iyenghar, Elke Pulvermueller   +2 more
doaj   +1 more source