Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
More than rapid identification—Free plant identification apps can also be highly accurate
People and NatureHart et al. (2023) conducted a study to evaluate the accuracy of five plant identification apps based on snapshot images as used in practice by field ecologists. Their results revealed varying accuracies per app, ranging from 86.9% to 46.4%.
Michael Rzanny +6 more
doaj +1 more source
Impacts of irrigated agriculture on food–energy–water–CO2 nexus across metacoupled systems
Nature Communications, 2020 Local human activities can lead to cross-border environmental impacts through the food–energy–water–CO2 nexus. Here, the authors report wide variations in environmental impacts of irrigated agriculture across counties within the North China Plain under ...
Zhenci Xu +9 more
doaj +1 more source
Editorial: Frontiers in dental medicine: highlights in systems integration 2021/22. [PDF]
Front Dent Med, 2023 Chu E, Nociti FH.
europepmc +1 more source
IEEE Transactions on Very Large Scale Integration (VLSI) Systems
IEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2019 The IEEE TRANSACTIONS ON VERY LARGE SCALE INTEGRATION (VLSI) SYSTEMS is published as a monthly journal under the co-sponsorship of the IEEE Circuits and Systems Society, the IEEE Computer Society, and the IEEE Solid-State Circuits Society. All members of
Magdy Abadir
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Adaptive service discovery on service-oriented and spontaneous sensor systems [PDF]
, 2012 Service-oriented architecture, Spontaneous networks, Self-organisation, Self-configuration, Sensor systems, Social patternsNatural and man-made disasters can significantly impact both people and environments.
Antonopoulos, Nikolaos +4 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Restructuring Non-teaching Hospitals into Teaching Hospitals in Iran: Component Change in General Hospitals [PDF]
Journal of Qualitative Research in Health SciencesBackground: The present study investigated how a general hospital is restructured in Iran when transforming from a non-teaching into a teaching hospital.Methods: This applied study was conducted based on a mixed-method design from 2020 to 2021 using a ...
Niusha Shahidi Sadeghi +4 more
doaj +1 more source
Neurons and symbols: a manifesto [PDF]
, 2010 We discuss the purpose of neural-symbolic integration including its principles, mechanisms and applications. We outline a cognitive computational model for neural-symbolic integration, position the model in the broader context of multi-agent systems ...
Garcez, A.
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