Results 111 to 120 of about 1,162,431 (318)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Journal of Public Health Research, 2016 Health informatics has a major role to play in optimising the management and use of data, information and knowledge in health systems. As health systems undergo digital transformation, it is important to consider informatics approaches not only to ...
Kathleen Gray
doaj +1 more source
Editorial: Frontiers in dental medicine: highlights in systems integration 2021/22. [PDF]
Front Dent Med, 2023 Chu E, Nociti FH.
europepmc +1 more source
2-D and 3-D Integration of Heterogeneous Electronic Systems under Cost, Performance and Technological Constraints [PDF]
, 2009 —Present day market demand for high-performance high-density portable hand-held applications has shifted the focus from 2-D planar system-on-a-chip-type single-chip solutions to al-ternatives such as tiled silicon and single-level embedded modules as ...
Pamunuwa, D. +13 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Integrity in Information Systems [PDF]
, 1997 This paper has been produced in October 1994 as a working paper for the City University Business School, in the context of the activities of IFIP TC-11 Working Group 11.5. This working group addresses “Integrity and Internal Control in Information Systems” within the overall remit of Technical Committee 11 (TC-11) “Security and Protection in ...
William List, W. R. Melville
openaire +1 more source
A national approach to systems integration of large complex systems
, 2004 Large-scale systems, such as rail networks, air traffic control systems, and networked defence systems are vital to national well-being. However, modern systems are becoming increasingly complex in nature and their development is proving problematical ...
Nandagopal, D. +5 more
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The U.S. civil service personnel management system: a human-organization interface view [PDF]
, 2014 Human Systems Integration (HSI) CapstoneThe federal government’s rigidly structured civil service personnel management system creates a climate of inflexibility and stasis, where length of service is prioritized above innovative, responsive performance ...
Kilgore, Maura Rudy
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source