Results 111 to 120 of about 4,023,339 (305)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Heterogeneous Autonomous Robotic System in Viticulture and Mariculture: Vehicles Development and Systems Integration. [PDF]

Sensors (Basel), 2022
Kapetanović N, Goričanec J, Vatavuk I, Hrabar I, Stuhne D, Vasiljević G, Kovačić Z, Mišković N, Antolović N, Anić M, Kozina B.   +10 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Need for a systems integration methodology for effective implementation of simulation-based training. [PDF]

Ann Thorac Med, 2021
Johnson PA, Johnson JC.
europepmc   +1 more source

Change, Coordination, and Capabilities [PDF]

Empirical studies on coordination of economic activities focused on the two polar cases of governance mode, namely vertical integration and market exchanges. Whether firms should be vertically integrated or lever market exchanges in the face of change is,
Andrea Prencipe
core  

Adaptive service discovery on service-oriented and spontaneous sensor systems [PDF]

, 2012
Service-oriented architecture, Spontaneous networks, Self-organisation, Self-configuration, Sensor systems, Social patternsNatural and man-made disasters can significantly impact both people and environments.
Antonopoulos, Nikolaos, Li, Jianxin, Liu, Lu, Wu, Kaigu, Xu, Jie   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The complexity of scaling up an mHealth intervention: the case of SMS for Life in Tanzania from a health systems integration perspective. [PDF]

BMC Health Serv Res, 2021
Sant Fruchtman C, Mbuyita S, Mwanyika-Sando M, Braun M, de Savigny D, Cobos Muñoz D.   +5 more
europepmc   +1 more source

Process and information integration via hypermedia [PDF]

Success stories for advanced automation prototypes abound in the literature but the deployments of practical large systems are few in number. There are several factors that militate against the maturation of such prototypes into products.
Hammen, David G., Labasse, Daniel L., Myers, Robert M.   +2 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source