Results 161 to 170 of about 399,149 (348)

Comparative Analysis of Gut Microbiota from Rats Induced by Se Deficiency and T-2 Toxin. [PDF]

Nutrients, 2023
Wu Y, Gong Y, Zhang Y, Li S, Wang C, Yuan Y, Lv X, Liu Y, Chen F, Chen S, Zhang F, Guo X, Wang X, Ning Y, Zhao H.   +14 more
europepmc   +1 more source

Alteration of Key Cytokine Levels by Aflatoxin B\u3csub\u3e1\u3c/sub\u3e and T-2 Toxin in Male CD-1 Mice [PDF]

, 1995
Aflatoxin B1 and T-2 toxin are mycotoxins, which produce their immunotoxic effects by affecting nonspecific and acquired immunity in different species. The mechanisms of their immunotoxicity are still obscure.
Dugyala, Raviprakash R.
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Inhibition at the initiation level of eukaryotic protein synthesis by T‐2 toxin [PDF]

, 1975
Kelvin E. Smith, Michael Cannon, Eric Cundliffe   +2 more
openalex   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Gas-Liquid Chromatographic Determination of T-2 Toxin and Diacetoxyscirpenol in Corn and Mixed Feeds [PDF]

, 1978
Thomas R Romer, Tamara M Boling, John L. MacDonald   +2 more
openalex   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

T-2 toxin-induced testicular impairment by triggering oxidative stress and ferroptosis

Ecotoxicology and Environmental Safety
T-2 toxin is a trichothecene mycotoxin of significant danger to humans and animals. Its impact on reproductive toxicity is attributed to oxidative stress, which ultimately leads to cell death.
Jun He, Hong Jin, Jiabin Guo, Kexin Li, Li Jia, Yujie Li, Li Zhang   +6 more
doaj  

Application of an enzyme-linked immunosorbent assay for screening of T-2 toxin-producing Fusarium spp [PDF]

, 1988
Satoshi Nagayama, Osamu Kawamura, Keishi Ohtani, Jae‐Chun Ryu, D. Latus, L Sudheim, Yuji Ueno   +6 more
openalex   +1 more source

The Role of Homeostatic Imbalance in the Reported Immunomodulation of T-2 Toxin [PDF]

, 1988
T-2 toxin (T-2), produced by the genus Fusarium, is a cytotoxic trichothecene mycotoxin, a feed contaminant, and has been shown to be immunomodulatory.
Taylor, Michael Jay
core   +1 more source