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Comprehensive Analysis of T-2 Toxin Contamination in Maize from Northeast China Using Automated Immunomagnetic Beads System Coupled with Lc-Ms/Ms

Biaohua Chen, Di Cai, Peng Li, Jin Ye, Meng Wang, Yu Wu, Li Li, Hongmei Liu, Qinghui Zhang, Yao Qin, Quan Pan, Songxue Wang   +11 more
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Review of neurotoxicity of T-2 toxin

Mycotoxin Research
T-2 toxin is a representative trichothecene that is widely detected in corn, wheat and other grain feeds. T-2 toxin has stable physical and chemical properties, making it difficult to remove from food and feed. Hence, T-2 toxin has become an unavoidable pollutant in food for humans and animals.
Youshuang Wang, Bo Wang, Peilin Wang, Zeao Hua, Shanshan Zhang, Xuebing Wang, Xu Yang, Cong Zhang   +7 more
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Selenium Improves Bone Microenvironment-Related Hematopoiesis and Immunity in T-2 Toxin-Exposed Mice.

Journal of Agricultural and Food Chemistry, 2023
The T-2 toxin is one of the most frequent contaminants in the environment and agricultural production globally. It exerts a wide range of toxic effects.
Jian Zhang, Yanfei Han, Miao Song, Qi Wang, Zheng Cao, Xu Yang, Yanfei Li   +6 more
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T-2 Toxin Caused Mice Testicular Inflammation Injury via ROS-Mediated NLRP3 Inflammasome Activation.

Journal of Agricultural and Food Chemistry, 2022
T-2 toxin treatment causes male reproduction system dysfunction, although the exact mechanism remains unclear. In this research, male Kunming mice and TM4 cells were treated with varying concentrations of the T-2 toxin for evaluating the adverse effect ...
Xu Yang, Pengli Liu, Yilong Cui, Miao Song, Xuliang Zhang, Cong Zhang, Yibao Jiang, Yanfei Li   +7 more
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T-2 Toxin Induces Kidney Fibrosis via the mtROS-NLRP3-Wnt/β-Catenin Axis.

Journal of Agricultural and Food Chemistry, 2022
T-2 toxin causes kidney fibrosis. Wnt/β-catenin signaling promotes kidney fibrosis when sustained and activated. However, whether T-2-induced kidney fibrosis involves Wnt/β-catenin signaling activation has not been explored yet.
Xuliang Zhang, B. Li, Siming Huo, Jiayu Du, Jian Zhang, Miao Song, Yilong Cui, Yanfei Li   +7 more
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T‐2 toxin‐induced femur lesion is accompanied by autophagy and apoptosis associated with Wnt/β‐catenin signaling in mice

Environmental Toxicology, 2022
T‐2 toxin is one of the most common mycotoxins found in grain foods, animal feed, and other agricultural by‐products causing food contamination and health threat. The skeletal system is the main target tissue for T‐2 toxin.
Jian Zhang, Miao Song, Yilong Cui, B. Shao, Xuliang Zhang, Zheng Cao, Yanfei Li   +6 more
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T-2 Toxin Induces Ferroptosis by Increasing Lipid Reactive Oxygen Species (ROS) and Downregulating Solute Carrier Family 7 Member 11 (SLC7A11).

Journal of Agricultural and Food Chemistry, 2021
T-2 toxin is a trichothecene mycotoxin commonly found in animal feed and agricultural products. Evidence indicates that T-2 toxin induces apoptosis and autophagy. This study investigated the role of ferroptosis in T-2 toxin cytotoxicity.
Guoyan Wang, Senlin Qin, YiNing Zheng, Chao Xia, Pei Zhang, Linxuan Zhang, Junhu Yao, Yanglei Yi, Lu Deng   +8 more
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Immunoperoxidase localization of T-2 toxin

Toxicology and Applied Pharmacology, 1984
Antibody against T-2 toxin was used for monitoring the fate of T-2 toxin in mice given a single po dose of 11 mg/kg by the peroxidase-antiperoxidase (PAP) method. T-2 toxin was demonstrable in the esophagus from 5 min to about 24 hr postdosing. In the stomach, T-2 toxin was detected within the cytoplasm of intact and injured epithelial cells.
S C, Lee, J T, Beery, F S, Chu
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Metabolic Pathways of T-2 Toxin

Current Drug Metabolism, 2008
Among the naturally-occurring trichothecenes found in food and feed, T-2 toxin is the most potent and toxic mycotoxin. After ingestion of T-2 toxin into the organism, it is processed and eliminated. Some metabolites of this trichothecene are equally toxic or slightly more toxic than T-2 itself, and therefore, the metabolic fate of T-2 toxin has been of
Vlastimil, Dohnal, Alena, Jezkova, Daniel, Jun, Kamil, Kuca   +3 more
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A review of the reproductive toxicity of T-2 toxin.

Journal of Agricultural and Food Chemistry, 2020
T-2 toxin, an inevitable environmental pollutant, is the most toxic type A trichothecene mycotoxin. Reproductive disruption is a key adverse effect of T-2 toxin. Herein, this paper reviews the reproductive toxicity of T-2 toxin and its mechanisms in male
Xu Yang, Pengli Liu, Yilong Cui, B. Xiao, Menglin Liu, Miao Song, Wanyue Huang, Yanfei Li   +7 more
semanticscholar   +1 more source