Results 171 to 180 of about 2,650,641 (236)
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Chromatographic enzyme immunoassay for T-2 toxin

Journal of Immunological Methods, 1990
Both the active ester and maleimide moieties of the cross-linking reagent, N-[(gamma-maleimidobutyryl)oxy]succinimide (GMBS), were found to react with the primary amino groups on ribonuclease (RNase). This largely inactivated RNase towards a polymeric (but not monomeric) substrate.
B A, Warden   +5 more
openaire   +2 more sources

T-2 Toxin

Journal of the American Veterinary Medical Association, 1973
SUMMARY Fusarium tricinctum is consistently the most toxigenic fungus isolated from moldy corn in low-temperature storage. Isolants of this fungus produce T-2 toxin, diacetoxyscirpenol, and a butenolide. The acute oral ld50 of T-2 toxin is approximately 4 mg./kg. of body weight in swine and rats and 6.5 mg./kg. of body weight in rainbow trout.
openaire   +2 more sources

Cross-reactivity of antibodies against T-2 with deepoxide T-2 toxin

Mycotoxin Research, 1988
Two types of antibodies raised against T-2 toxin, namely anti-T-2-HS-BSA and anti-3 -Ac -NEOS-HS -BSA, showed good cross-reactivity with deepoxy T-2 toxin. Our results indicate that the epoxide is not an important epitope for the production of antibody against T-2 toxin.
R D, Wei, S P, Swanson, F S, Chu
openaire   +2 more sources

Overview of T-2 Toxin Enterotoxicity: From Toxic Mechanisms and Detoxification to Future Perspectives.

Journal of Agricultural and Food Chemistry
Fusarium species produce a secondary metabolite known as T-2 toxin, which is the primary and most harmful toxin found in type A trichothecenes. T-2 toxin is widely found in food and grain-based animal feed and endangers the health of both humans and ...
Shanshan Zhang   +7 more
semanticscholar   +1 more source

Removal of aflatoxin b1 and t-2 toxin by bacteria isolated from commercially available probiotic dairy foods

Food science and technology international = Ciencia y tecnologia de los alimentos internacional, 2021
This study isolated lactic acid bacteria from commercially available probiotic foods to determine their capacity to remove aflatoxin B1 (AFB1) and trichothecene-2 (T-2).
Walter Ondiek   +6 more
semanticscholar   +1 more source

The structure of T-2 toxin

Acta Crystallographica Section C Crystal Structure Communications, 1990
C 24 H 34 O 9 cristallise dans P2 1 2 1 2 1 avec a=7,808, b=15,800, c=40,891 A, z=8; affinement jusqu'a R=0,055. La formule structurale etablie chimiquement a ete corroboree. Les deux molecules dans la maille asymetrique different seulement par leurs angles de torsion des chaines ester ...
R. Gilardi   +2 more
openaire   +1 more source

Interaction of T-2 toxin with murine lymphocytes

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1984
T-2 toxin is taken up by lymphocytes in 10-15 min in a saturable manner. Uptake is dependent on temperature and partially on the availability of energy. Approx. 10(5) molecules of T-2 toxin are bound per cell, having a mean affinity constant, Ka = 1.6 X 10(7) M-1. The toxin is rapidly dissociated from the cell to leave approx.
Gyongyossy, issa M, Khachatourians, G G
openaire   +2 more sources

Cardiomyopathy induced by T-2 toxin in rats

Food and Chemical Toxicology, 2020
T-2 toxin, A trichothecenes mycotoxin, is immunotoxic to animals and humans. Although it is highly cardiotoxic, the pathogenesis of cardiomyopathy caused by T-2 toxin is not entirely clear. Hence, in our research, cardiomyopathy was induced by a single injection of T-2 mycotoxin (0.23 mg/kg s.c., 1 LD50) to Wistar rats. The cardiac tissue was carefully
Vesna Jaćević   +3 more
openaire   +2 more sources

Metabolic effects of trichothecene T-2 toxin

Canadian Journal of Physiology and Pharmacology, 1990
Cereals and other agricultural products contaminated with trichothecene mycotoxins are unfit for consumption. Until recently, the metabolic effects of T-2 toxin (T-2) were thought to reside in its ability to inhibit protein synthesis. It is now clear that trichothecenes have multiple effects, including inhibition of DNA, RNA, and protein synthesis in ...
openaire   +2 more sources

T-2 toxin is hydroxylated by chicken CYP3A37

Food and Chemical Toxicology, 2013
T-2 toxin (T-2) is an acute toxic trichothecene mycotoxin produced mainly by Fusarium species, detected in many crops including oats, wheat and barley, in animal feed and food. It is important to know the metabolic pathway and kinetics of T-2 in food animals given that T-2 can cause serious adverse effects on human health.
Yiyang, Yuan   +4 more
openaire   +2 more sources

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