Results 31 to 40 of about 383,521 (254)

miR449a/SIRT1/PGC-1α Is Necessary for Mitochondrial Biogenesis Induced by T-2 Toxin

open access: yesFrontiers in Pharmacology, 2018
T-2 toxin is one of the type A trichothecenes produced mainly by the Fusarium genus. Due to its broad distribution and highly toxic nature, it is of great concern as a threat to human health and animal breeding.
Shijie Ma   +8 more
doaj   +1 more source

Survey for Fusaria That Elaborate T-2 Toxin [PDF]

open access: yesApplied Microbiology, 1972
Of the 136 strains of Fusarium examined, T-2 toxin was confirmed by thinlayer chromatography in 13 of the 21 extracts that inhibited either Rhodotorula rubra or Pencillium digitatum .
H R, Burmeister   +2 more
openaire   +2 more sources

The role of mitochondria in T-2 toxin-induced human chondrocytes apoptosis. [PDF]

open access: yesPLoS ONE, 2014
T-2 toxin, a mycotoxin produced by Fusarium species, has been shown to cause diverse toxic effects in animals and is also a possible pathogenic factor of Kashin-Beck disease (KBD). The role of mitochondria in KBD is recognized in our recent research. The
Jiangtao Liu   +7 more
doaj   +1 more source

Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells

open access: yesToxins, 2019
T-2 toxin is a mycotoxin generated by Fusarium species which has been shown to be highly toxic to human and animals. T-2 toxin induces apoptosis in various tissues/organs.
Jing Wu   +6 more
doaj   +1 more source

Evaluation of mycofix to ameliorate the toxic effect of t-2 toxin on performance of broiler chickens [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2007
The possible protective effect of Mycofix against the toxic effect of T-2 toxin in growing broiler chickens was investigated in two age stages; the first and second ages, ranged from 1-21 and 22-42 days, respectively.
A. M. Shareef, Z. A. Jameel
doaj   +1 more source

T-2 Toxin: Incidence and Toxicity in Poultry [PDF]

open access: yesArchives of Industrial Hygiene and Toxicology, 2008
T-2 Toxin: Incidence and Toxicity in PoultryT-2 toxin is the most toxic type A trichothecene mycotoxin. It is the secondary metabolite of the Fusarium fungi, and is common in grain and animal feed. Toxic effects have been shown both in experimental animals and in livestock. It has been implicated in several outbreaks of human mycotoxicoses.
Sokolović, Marijana   +2 more
openaire   +4 more sources

Patient Activation in Childhood, Adolescent, and Young Adult Cancer Survivors: Current Insights and Implications for Survivorship Care—A Systematic Review From the e‐QuoL Project

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Patient activation—encompassing knowledge, confidence, and skills in managing individual's health—is a cornerstone of person‐centered care. However, its significance among childhood, adolescent, and young adult cancer survivors (CAYACS) remains unexplored. This article examines the application of the 13‐item Patient Activation Measure (
Charlotte Demoor‐Goldschmidt   +12 more
wiley   +1 more source

T-2 toxin and deoxynivalenol (DON) exert distinct effects on stress granule formation depending on altered activity of SIRT1

open access: yesEcotoxicology and Environmental Safety, 2023
The T-2 toxin and deoxynivalenol (DON), as the most concerned members of trichothecenes, induce cellular stress responses and various toxic effects. Stress granules (SGs) are rapidly formed in response to stress and play an important role in the cellular
Tianqing Jiang   +5 more
doaj   +1 more source

Radioimmunoassay of T-2 Toxin in Biological Fluids

open access: yesJournal of AOAC INTERNATIONAL, 1981
Abstract A simple radioimmunoassay (RIA) for detection of T-2 toxin in biological fluids was developed. The method, which involves a Sep-Pak C18 reverse phase column cleanup step before RIA, can detect 0.5 ppb T-2 toxin in serum and 2.5 ppb T-2 toxin in urine and milk. Recoveries for toxin added to serum and urine or milk samples were 87-
S, Lee, F S, Chu
openaire   +2 more sources

Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya   +10 more
wiley   +1 more source

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