Results 131 to 140 of about 2,668,255 (357)

Production of soluble IL-4 receptors by murine spleen cells is regulated by T cell activation and IL-4. [PDF]

, 1993
Paula M. Chilton, Rafael Fernandez-Botrán   +1 more
openalex   +1 more source

Fibroma, a Noval Side Effect of Chimeric Antigen Receptor (Car) T-Cell Immunotherapy in a Patient with Diffuse Large B-Cell Lymphoma: A Case Report

, 2021
Lihang Lin, Changhua Zhu
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Chimeric antigen receptor T-cell therapy for T-cell acute lymphoblastic leukemia

Haematologica
Chimeric antigen receptor (CAR) T-cell therapy is a new and effective treatment for patients with hematologic malignancies. Clinical responses to CAR T cells in leukemia, lymphoma, and multiple myeloma have provided strong evidence of the antitumor ...
Bernice L.Z. Oh, Natasha Vinanica, Desmond M.H. Wong, Dario Campana   +3 more
doaj   +1 more source

[Structural optimization and prospect of chimeric antigen receptor T cells].

, 2021
Cya Tong, Y Wang, Wei Han
openalex   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Some Hints Concerning the Shape of T‐Cell Receptor Structures [PDF]

, 2002
Bent Rubin, Laeticia Alibaud, Anne Huchenq-Champagne, J. Arnaud, Marı́a L. Toribio, J. Constans   +5 more
openalex   +1 more source

T cell recognition of nonpolymorphic determinants on H-2 class I molecules. [PDF]

, 1988
Recognition of polymorphic determinants on class I or class II MHC Ag is required for T lymphocyte responses. Using cell-size artificial membranes (pseudocytes) bearing H-2 class I Ag it is demonstrated that T cells can, in addition, recognize ...
Goldstein, SA, Mescher, MF
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Production of a T cell hybridoma that expresses the T cell receptor gamma/delta heterodimer. [PDF]

, 1987
We have produced a T cell hybridoma line by fusion of an IL-2-dependent, long-term T cell receptor (TCR) gamma/delta+ Thy-1+, bone marrow-derived, dendritic epidermal cell line to the BW5147 tumor line.
Bluestone, JA, Coligan, JE, Koning, F, Shevach, EM, Stingl, G, Yokoyama, WM   +5 more
core