Results 201 to 210 of about 2,529,459 (356)

Analysis of a monoclonal rat antibody directed to the alpha-chain variable region (V alpha 3) of the mouse T cell antigen receptor. [PDF]

, 1989
Yasunori Utsunomiya, J Bill, Ed Palmer, Kenneth J. Gollob, Yohtaroh Takagaki, Osami Kanagawa   +5 more
openalex   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Association of antibody and T cell receptor repertoires in Trypanosoma cruzi infected rhesus macaques and host response to infection. [PDF]

J Biomed Sci
Clear RM, Tu W, Goff K, Marx PA, Herrera C, Dumonteil E.   +5 more
europepmc   +1 more source

Defective cell-mediated immunity in leprosy: failure of T cells from lepromatous leprosy patients to respond to Mycobacterium leprae is associated with defective expression of interleukin 2 receptors and is not reconstituted by interleukin 2. [PDF]

, 1985
Nahid Mohagheghpour, R H Gelber, J W Larrick, Dennis T. Sasaki, P J Brennan, Edgar G. Engleman   +5 more
openalex   +1 more source

Sequence and evolution of the human T-cell antigen receptor beta-chain genes.

, 1985
Alan Tunnacliffe, Richard Kefford, César Milstein, A. Förster, Terence H. Rabbitts   +4 more
openalex   +1 more source

Activation of murine T lymphocytes with monoclonal antibodies: detection on Lyt-2+ cells of an antigen not associated with the T cell receptor complex but involved in T cell activation. [PDF]

, 1987
Oberdan Léo, M Foo, David M. Segal, Ethan M. Shevach, Jeffrey A. Bluestone   +4 more
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Molecular basis underpinning MR1 allomorph recognition by an MR1-restricted T cell receptor. [PDF]

Front Immunol
Suckling RJ, Pamukcu C, Simmons RA, Fonseca D, Grant E, Harrison R, Shaikh SA, Khanolkar RC, Ghadbane H, Creese A, Hock M, Gligoris TG, Lepore M, Karuppiah V, Salio M.   +14 more
europepmc   +1 more source

Receptor diversity of insulin-specific T cell lines from C57BL (H-2b) mice. [PDF]

, 1987
Dominic G. Spinella, Torbjørn Hansen, William D. Walsh, Mark A. Behlke, Jeffrey Tillinghast, Hubert S. Chou, P J Whiteley, J A Kapp, C W Pierce, E M Shevach   +9 more
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source