Results 211 to 220 of about 2,668,255 (357)

T-cell Receptor Profiling of Blood to Detect Lung Cancer. [PDF]

Cancer Immunol Res
Søgaard MT, Tseng D, Gibbs S, Wu W, Nolan LG, Yang PY, Lai M, Cao J, Pipavath S, Mayer-Blackwell K, Newell EW, Houghton AM, Payne KK, Chiou SH, Nair VS.   +14 more
europepmc   +1 more source

Apoptosis of Human T-Cell Acute Lymphoblastic Leukemia Cells by Diphenhydramine, an H1 Histamine Receptor Antagonist

, 2004
Shawkat-Muhialdin Jangi, Aintzane Asumendi, Jon Arluzea, Naiara Nieto, Gorka Pérez‐Yarza, María–Celia Morales, María de la Fuente, María Dolores Boyano   +7 more
openalex   +1 more source

Alterations in the T-Cell Receptor Variable β Gene–Restricted Profile of CD8+ T Lymphocytes in the Peripheral Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck [PDF]

, 2006
Andreas E. Albers, Carmen Visús, Takashi Tsukishiro, Robert L. Ferris, William E. Gooding, Theresa L. Whiteside, Albert B. De Leo   +6 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

High pretreatment peripheral blood T-cell receptor clonality as a predictor of prolonged response in immune thrombocytopenia. [PDF]

Br J Haematol
Schmidt-Barbo P, Schultheiss C, Jauch AJ, Simnica D, Silling G, Hänel M, Chromik J, Stauch T, Trautmann-Grill K, Repp R, Schulte C, Fleischmann B, Welslau M, Stauch M, Quiering C, Richter F, Tesanovic T, Jahn S, Holbro A, Passweg JR, Matzdorff A, Rummel M, Meyer O, Nimmerjahn F, Binder M.   +24 more
europepmc   +1 more source

Expansion of a unique subpopulation of cytotoxic T cells that express a C alpha V delta 1 T-cell receptor gene in a patient with severe persistent neutropenia [PDF]

, 1992
Ilan Bank, Mazal Book, Lena Cohen, A. Kneller, E Rosental, M Pras, IB Bassat, A Ben-Nun   +7 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Quantitative V gene-targeted T cell receptor sequencing as a biomarker in type 1 diabetes. [PDF]

JCI Insight
Landry LG, Wells KL, Anderson AM, Miller KR, Jones KL, Michels AW, Nakayama M.   +6 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Identification of a type 1 diabetes-associated T cell receptor repertoire signature from the human peripheral blood. [PDF]

Sci Adv
Rawat P, Shapiro MR, Peters LD, Widrich M, Mayer-Blackwell K, Motwani K, Pavlović M, Al Hajj G, Posgai AL, Kanduri C, Isacchini G, Chernigovskaya M, Scheffer L, Motwani K, Balzano-Nogueira LO, Pettenger-Willey CM, Valkiers S, Jacobsen LM, Haller MJ, Schatz DA, Wasserfall CH, Emerson RO, Fiore-Gartland AJ, Atkinson MA, Klambauer G, Sandve GK, Greiff V, Brusko TM.   +27 more
europepmc   +1 more source