A distinct subset of human CD4+ cells with a limited alloreactive T cell receptor repertoire. [PDF]
Y Morishita+3 more
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Lymphomatoid Papulosis Type E With T-Cell Receptor Gamma Positivity. [PDF]
Namasondhi A+4 more
europepmc +1 more source
The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype. [PDF]
Neal W. Roehm+6 more
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Distinct T Cell Subset Profiles and T-Cell Receptor Signatures in Metabolically Unhealthy Obesity. [PDF]
Chung Y+8 more
europepmc +1 more source
Functional isotypes are not encoded by the constant region genes of the beta subunit of the T cell receptor for antigen/major histocompatibility complex. [PDF]
H D Royer+3 more
openalex +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
T cell receptor activation contributes to brain damage after intracerebral hemorrhage in mice. [PDF]
Xiu Y+14 more
europepmc +1 more source
Functional analysis of the interaction of the antigen-specific T cell receptor with its ligands. [PDF]
Jonathan D. Ashwell+2 more
openalex +1 more source