Results 281 to 290 of about 4,863,715 (431)

Evaluation of T Cell Receptor Construction Methods from scRNA-Seq Data. [PDF]

Genomics Proteomics Bioinformatics
Tian R, Yu Z, Xue Z, Wu J, Wu L, Cai S, Gao B, He B, Zhao Y, Yao J, Lu L, Liu W.   +11 more
europepmc   +1 more source

Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies. [PDF]

, 1983
J. Michael White, Kathryn Haskins, Philippa Marrack, John W. Kappler   +3 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Masked language modeling pretraining dynamics for downstream peptide: T-cell receptor binding prediction. [PDF]

Bioinform Adv
Landry B, Zhang J.
europepmc   +1 more source

T3-p28 is a protein associated with the delta and epsilon chains of the T cell receptor-T3 antigen complex during biosynthesis.

, 1987
Carolyn L. Pettey, Balbino Alarcón, Robert Malin, Kenneth I. Weinberg, Cox Terhorst   +4 more
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Purification and NH2-terminal amino acid sequencing of the beta subunit of a human T-cell antigen receptor. [PDF]

, 1984
Oreste Acuto, Marina Fabbi, J. E. Smart, Catherine B. Poole, J Protentis, H D Royer, Stuart F. Schlossman, E L Reinherz   +7 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The compositional behavior of the human T cell receptor repertoire in ovarian cancer compared to healthy donors. [PDF]

Sci Data
Zuckerbrot-Schuldenfrei M, Zilberberg A, Efroni S.   +2 more
europepmc   +1 more source

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

Nature, 1988
P. Kisielow, H. Blüthmann, U. Staerz, M. Steinmetz, H. Boehmer   +4 more
semanticscholar   +1 more source