Results 291 to 300 of about 4,863,715 (431)

Specificity of the T cell receptor: two different determinants are generated by the same peptide and the I-Ak molecule. [PDF]

, 1985
Paul M. Allen, Gary R. Matsueda, E Haber, Emil R. Unanue   +3 more
openalex   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Characterization of T-Cell Receptor Profiles Predicts Survival Situation in Patients with Hepatocellular Carcinoma. [PDF]

Technol Cancer Res Treat
Wang F, Deng L, Li Z, Cao Q, Jiang R, Xu C, Yang J.   +6 more
europepmc   +1 more source

Signal transduction of gamma/delta T cell antigen receptor with a novel mitogenic anti-delta antibody. [PDF]

, 1988
Yujing Wu, W T Tian, R. Michael Snider, Charles W. Rittershaus, P Rogers, L LaManna, S H Ip   +6 more
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Predicting T cell receptor functionality against mutant epitopes. [PDF]

Cell Genom
Drost F, Dorigatti E, Straub A, Hilgendorf P, Wagner KI, Heyer K, López Montes M, Bischl B, Busch DH, Schober K, Schubert B.   +10 more
europepmc   +1 more source

T Cell Receptors and Immunoregulation [PDF]

Journal of the Royal Society of Medicine, 1985
openaire   +3 more sources

Different gamma delta T-cell receptors are expressed on thymocytes at different stages of development.

, 1989
Kouichi Ito, Marc Bonneville, Yohtaroh Takagaki, Nagayasu Nakanishi, Osami Kanagawa, E G Krecko, Susumu Tonegawa   +6 more
openalex   +1 more source

Specificity of the T cell immune response to acetylcholine receptor in experimental autoimmune myasthenia gravis. Response to subunits and synthetic peptides. [PDF]

, 1988
Yoshitaka Fujii, J Lindström
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source