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2003
The antigen receptor expressed on most T-lymphocytes (T-cell antigen receptor [TCR]) is a multisubunit complex consisting of at least six different polypeptides (α, β, γ, δ, ɛ, and ζ), several of which are modified by addition of N-linked oligosaccharide chains Oligosaccharide side chains on TCR glycoproteins undergo well-characterized processing ...
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The antigen receptor expressed on most T-lymphocytes (T-cell antigen receptor [TCR]) is a multisubunit complex consisting of at least six different polypeptides (α, β, γ, δ, ɛ, and ζ), several of which are modified by addition of N-linked oligosaccharide chains Oligosaccharide side chains on TCR glycoproteins undergo well-characterized processing ...
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T Cell Receptor Repertoire Sequencing
2020The status of T cell receptors (TCRs) repertoire is associated with the occurrence and progress of various diseases and can be used in monitoring the immune responses, predicting the prognosis of disease and other medical fields. High-throughput sequencing promotes the studying in TCR repertoire.
Huixin, Lin +5 more
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Cellular and Molecular Life Sciences, 2006
Gamma delta (gamma delta) T cells are among the least understood components of the immune system. While these cells appear to contribute uniquely to host immune competence, defining their functions in the context of host biology and pathology has been difficult.
Y-h, Chien, M, Bonneville
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Gamma delta (gamma delta) T cells are among the least understood components of the immune system. While these cells appear to contribute uniquely to host immune competence, defining their functions in the context of host biology and pathology has been difficult.
Y-h, Chien, M, Bonneville
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Antigen-specific T cell receptors
1987Publisher Summary This chapter discusses immunoglobulin-related T cell receptors. It also presents the production of antibodies to both antigen-binding T cell receptors that are known to be related to immunoglobulin variable regions and to the α/β heterodimers that do not bind antigen, but are encoded by rearranged genes showing sufficient homology ...
J J, Marchalonis, S F, Schluter
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T cell antigen receptor antibodies
Nature, 1987Immunology has a long tradition of using the immune system to study the immune system. Monoclonal antibodies are now being focused upon the antigen receptor of the T lymphocyte.
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Human T cell receptor gamma delta + T cells.
Seminars in immunology, 1991TCR gamma delta + T cells represent a minority of CD3+ T cells in many species including man. The molecular structure of the TCR gamma and delta loci in man is well understood. The gamma and delta loci contain V, D, J and C gene segments. These segments do not rearrange randomly but in a coordinated, ordered fashion during thymic development. Therefore,
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Nature Reviews Immunology, 2002
T cells are tightly controlled cellular machines that monitor changes in epitope presentation. Although T-cell function is regulated by means of numerous interactions with other cell types and soluble factors, the T-cell receptor (TCR) is the only structure on the T-cell surface that defines its antigen-recognition potential. Consequently, the transfer
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T cells are tightly controlled cellular machines that monitor changes in epitope presentation. Although T-cell function is regulated by means of numerous interactions with other cell types and soluble factors, the T-cell receptor (TCR) is the only structure on the T-cell surface that defines its antigen-recognition potential. Consequently, the transfer
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JAMA: The Journal of the American Medical Association, 1988
A VERTEBRATE is an attractive culture medium for viruses, bacteria, fungi, and metazoan parasites. It is therefore understandable that vertebrates have had to develop a body defense mechanism directed toward these pathogens for their emergence and survival. This defense mechanism is the See also pp 1834 and 1837. immune system.
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A VERTEBRATE is an attractive culture medium for viruses, bacteria, fungi, and metazoan parasites. It is therefore understandable that vertebrates have had to develop a body defense mechanism directed toward these pathogens for their emergence and survival. This defense mechanism is the See also pp 1834 and 1837. immune system.
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