Results 311 to 320 of about 4,863,715 (431)

Hepatic T cell lymphoma after chimeric antigen receptor T cell therapy for myeloma

eJHaem
Joshua Mehr, Mingyi Chen
doaj   +1 more source

The intratumoral landscape of T cell receptor repertoire in esophageal squamous cell carcinoma. [PDF]

J Transl Med
Yang M, He D, Sun Y, Guo Y, Ma Y, Feng L, Liu M.   +6 more
europepmc   +1 more source

MIF as an oncogenic driver of low‐heterogeneity melanomas

Molecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran, Gabriela Athziri Sánchez‐Zuno, Rajan P. Kulkarni, Harriet M. Kluger, Richard Bucala   +4 more
wiley   +1 more source

A naturally selected αβ T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide. [PDF]

Nat Commun
Lim JJ, Jones CM, Loh TJ, Dao HT, Tran MT, Tye-Din JA, La Gruta NL, Rossjohn J.   +7 more
europepmc   +1 more source

Linking T-cell receptor sequence to functional phenotype at the single-cell level

Nature Biotechnology, 2014
A. Han, J. Glanville, L. Hansmann, Mark M. Davis   +3 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

T cell receptor sharing in hypersensitivity pneumonitis

Sendama W, Funston W, Davidson RC, Rostron AJ, Simpson AJ.   +4 more
europepmc   +1 more source

Synthetic T-Cell Receptor-like Protein Behaves as a Janus Particle in Solution. [PDF]

J Am Chem Soc
Sakamoto-Rablah E, Bye J, Modak A, Hooker A, Uddin S, McManus JJ.   +5 more
europepmc   +1 more source