Results 321 to 330 of about 4,863,715 (431)

Rearrangement and transcription of a T-cell receptor beta-chain gene in different T-cell subsets.

, 1985
Stephen Μ. Hedrick, Ronald N. Germain, Michael J. Bevan, Martin E. Dorf, Isaac Engel, Pamela J. Fink, Nicholas R. J. Gascoigne, Ellen Heber‐Katz, Judith A. Kapp, Yael Kaufmann   +9 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

T cell receptor signaling pathway subgroups and construction of a novel prognostic model in osteosarcoma. [PDF]

Heliyon
Xu H, Tao H.
europepmc   +1 more source

T-Cell Receptor Rearrangements in Early Stages of Mycosis Fungoides May Be Associated with Pronounced Copy Number Variations: A Prognostic Factor? [PDF]

Cancers (Basel)
Hain C, Cieslak C, Kalinowski J, Stadler R.   +3 more
europepmc   +1 more source

Sequence and evolution of the human T-cell antigen receptor beta-chain genes.

, 1985
Alan Tunnacliffe, Richard Kefford, César Milstein, A. Förster, Terence H. Rabbitts   +4 more
openalex   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

Harnessing antibody-mediated recognition of the intracellular proteome with T cell receptor-like specificity. [PDF]

Front Immunol
Haus-Cohen M, Reiter Y.
europepmc   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Engineered T Cell Receptor for Cancer Immunotherapy. [PDF]

Biomol Ther (Seoul)
Lee SW, Lee HM.
europepmc   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source