Results 321 to 330 of about 615,997 (368)
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Differential Regulation of Murine T Lymphocyte Subsets
Annual Review of Immunology, 1993Signaling pathways in T lymphocytes have been incompletely characterized. It is evident that differences exist among the T cell subsets. We have defined several distinct mechanisms that affect differentially the activities of murine T lymphocyte clones representing various CD4+ and CD8+ subsets: Interferon-gamma (IFN-gamma) inhibits proliferation of ...
F W, Fitch +3 more
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T-Lymphocyte Subsets and Schizophrenia
1987Viruses have long been sought as possible etiologic agents in several neurological and psychiatric disorders of unknown etiology such as amyotrophic lateral sclerosis (Zil’ber et al., 1963), multiple sclerosis (Marie, 1884), Parkinson’s disease (von Economo, 1931; Marttila et al., 1981), and schizophrenia (Menninger, 1922).
Charles A. Kaufmann +4 more
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T-lymphocyte subsets in experimental autoimmune uveitis
Clinical Immunology and Immunopathology, 1985The dynamic changes of the lymphocyte subsets in the inflamed ocular tissue in Lewis rats with experimental autoimmune uveitis (EAU) were studied by immunohistopathological evaluation at varying intervals after initiation of the disease. Monoclonal antibodies to specific markers of the rat T-helper/inducer lymphocyte (W3/25) and T-suppressor/cytotoxic ...
C C, Chan +6 more
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T-lymphocyte Subsets in Occupationally Exposed Persons
International Journal of Radiation Biology, 1990The percentage of CD2+, CD4+, CD8+ and HNK-1+ cells in peripheral blood was investigated in persons occupationally exposed to very low doses of ionizing radiation. Investigations were carried out by monoclonal antibodies and flow cytometry. While significant effects of age and smoking habits on the relative number of CD8 cells and CD4/CD8 ratios could ...
H, Tuschl, R, Kovac, A, Wottawa
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T-lymphocyte subsets in idiopathic dilated cardiomyopathy
The American Journal of Cardiology, 1985Idiopathic dilated cardiomyopathy (IDC) is a common clinical problem in Africa. To determine if there is a defect of immune regulation in patients with IDC, the percentage of total T-cells (OKT3 positive), helper/inducer cells (OKT4 positive) and suppressor/cytotoxic cells (OKT8 positive) were measured using monoclonal antibodies in 20 patients with ...
Sanderson, JE +3 more
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Modeling the lifespan of human T lymphocyte subsets
Mathematical Biosciences, 1997T lymphocytes may be classified as naive or memory cells, depending on whether they possess immunological memory. The central tenet of this work is that memory lymphocytes revert to naive lymphocytes in vivo. This phenomenon is modeled by a mechanism qualitatively similar to Demoivre's law of human mortality.
Hurn, A. S. +2 more
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Abnormal T-Lymphocyte Subsets in Type I Diabetes
Diabetes, 1989Type I (insulin-dependent) diabetes mellitus is a slow autoimmune disease associated with the selective destruction of β-cells in the islets of Langerhans. Recent studies in humans indicate that autoantibodies to insulin and islets of Langerhans appear years before overt diabetes and identify a normoglycemic prediabetic state. To determine whether type
D, Faustman +3 more
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T-lymphocyte-subsets in endocrine exophthalmos.
Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985), 1985Peripheral T-Lymphocyte subsets were analyzed with monolateral antibodies in 40 patients with Graves' ophthalmopathy. The 20 patients with untreated hyperthyroid exophthalmos showed a slight statistically not significant decrease in the percentage of total T-Lymphocytes and a statistically significant decrease with percentage of the OK T8 cells.
CENMAMO G +2 more
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Distribution of T lymphocyte subsets in human colostrum.
Journal of Immunology, 1982Lymphocytes were isolated from human colostrum and peripheral blood collected within 7 days postpartum. A 20-fold enrichment of lymphocytes from colostrum was achieved by centrifugal elutriation followed by equilibrium density gradient centrifugation ...
E. Richie +3 more
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Renewal rates of murine T-lymphocyte subsets
Cellular Immunology, 1990The proliferative dynamics of T-cell subsets in lymphoid organs of BALB/c mice have been evaluated by means of [3H]thymidine injections for up to 3 days, followed by FACS and autoradiography. In the thymus, cells positive for both CD4 and CD8 antigens were more rapidly renewed than single-positive cells.
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