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Clinical validation of a real‐time machine learning‐based system for the detection of acute myeloid leukemia by flow cytometry

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Machine‐learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies have described the clinical deployment of such models.
Lauren M. Zuromski   +10 more
wiley   +1 more source
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T lymphocyte subsets in cancer immunity: Friends or foes

Journal of Leukocyte Biology, 2018
Although immune‐based therapy is proving to be a success in several cancer types, only a set of patients appear to respond to immune checkpoint blockade including PD‐1 and CTLA‐4.
Dounia Chraa   +3 more
semanticscholar   +1 more source

Regulatory effects of resveratrol on glucose metabolism and T-lymphocyte subsets in the development of high-fat diet-induced obesity in C57BL/6 mice.

Food & Function, 2014
High-fat diet (HFD)-induced obesity is often associated with immune dysfunction. Resveratrol (trans-3,5,4'-trihydroxystilbene), which has well-founded immunity-related beneficial properties, was used to elucidate the regulatory effect on glucose ...
Bin Wang   +5 more
semanticscholar   +1 more source

Distribution of T lymphocyte subsets in human colostrum.

Journal of Immunology, 1982
Lymphocytes were isolated from human colostrum and peripheral blood collected within 7 days postpartum. A 20-fold enrichment of lymphocytes from colostrum was achieved by centrifugal elutriation followed by equilibrium density gradient centrifugation ...
E. Richie   +3 more
semanticscholar   +1 more source

T-lymphocyte subsets in lymph nodes from homosexual men.

Journal of the American Medical Association (JAMA), 1983
To evaluate further the immunodeficiency of homosexual men, blood and lymph node specimens were obtained from five homosexual men with lymphadenopathy and from seven homosexual men with Kaposi's sarcoma.
R. Modlin   +10 more
semanticscholar   +1 more source

T lymphocyte subsets in autoimmune thyroid diseases and subacute thyroiditis detected with monoclonal antibodies.

Journal of Clinical Endocrinology and Metabolism, 1983
Peripheral T lymphocyte subsets were analysed with monoclonal antibodies, by highly standardized fluorescence-activated cell sorter analysis instead of manual counting by the indirect immunofluorescence method, in autoimmune thyroid diseases and subacute
Y. Iwatani   +6 more
semanticscholar   +1 more source

In situ localization of T lymphocyte subsets in human paracoccidioidomycosis.

Journal of Medical and Veterinary Mycology, 1989
Immunohistochemical techniques using monoclonal antibodies to T lymphocyte subsets were used to characterize granulomas caused by Paracoccidioides brasiliensis.
M. Moscardi-Bacchi   +4 more
semanticscholar   +1 more source

Abnormal peripheral blood T-lymphocyte subsets in a subgroup of patients with COPD.

Chest, 2002
BACKGROUND Smoking may induce changes in T-lymphocyte subsets in peripheral blood. Abnormalities of T-lymphocyte subsets in peripheral blood and in BAL fluid, and increased CD8+ T lymphocytes in the airways have been reported in patients with COPD. These
W. Kim   +6 more
semanticscholar   +1 more source

Effect of qigong training on proportions of T lymphocyte subsets in human peripheral blood.

The American Journal of Chinese Medicine, 1995
The effect of Qigong training on proportions of T lymphocyte subsets was investigated in human peripheral blood. We observed that the ratio of CD4+/CD8+ T lymphocytes was increased as much as 50% in a trainee group who practiced Qigong training more than
H. Ryu   +5 more
semanticscholar   +1 more source

[Effects of Lycium barbarum polysaccharide on tumor microenvironment T-lymphocyte subsets and dendritic cells in H22-bearing mice].

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2005
OBJECTIVE To study the effects of Lycium barbarum polysaccharide (LBP) on tumor microenvironment T-lymphocyte subsets and dendritic cells in H22-bearing mice and the mechanisms for intervention of tumor immune escape by LBP.
Yan-Li He   +5 more
semanticscholar   +1 more source

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