Results 1 to 10 of about 209,628 (240)
Cytotoxic T lymphocytes could contribute in COVID-19-induced passing anosmia
Studia Medyczne, 2021 Several clinical reports have demonstrated a spectrum of neurological manifestations of COVID-19 patients with subsequent post-mortem neuropathological findings. The aim of the case description is to show spotty inflammatory lesions in the olfactory bulb,
Marcin Zaremba +2 more
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Клиническая онкогематология, 2022 Aim. To generate anti-CD87 CAR-T lymphocytes and to assess their in vitro functional activity. Materials & Methods. Т-lymphocytes isolated from healthy donor peripheral blood were transduced with the anti-CD87-CAR, T2A, and FusionRed gene coding ...
M. V. Neklesova +5 more
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Cytotoxic Granule Trafficking and Fusion in Synaptotagmin7-Deficient Cytotoxic T Lymphocytes
Frontiers in Immunology, 2020 Granules of cytotoxic T lymphocytes (CTL) are derived from the lysosomal compartment. Synaptotagmin7 (Syt7) appears to be the calcium sensor triggering fusion of lysosomes in fibroblasts. Syt7 has been proposed to control cytotoxic granule (CG) fusion in
Marwa Sleiman +3 more
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Медицинская иммунология, 2020 We studied sex differences lymphocytes subpopulations of peripheral blood in adult C57Bl/6 mice during acute and chronic colitis, induced with 1% DSS. We measured subpopulations of lymphocytes with flow cytometry.
O. V. Makarova +3 more
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Healthy aging—would cytotoxic T lymphocytes stand out?
Cell Death Discovery, 2023 Senescent cells (SnCs) accumulate in multiple tissue types with the process of individual aging, hindering tissue renewal and driving multiple aging-related disorders.
Tianyu Zhang, Jinjin Zhang, Shixuan Wang
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Сибирский онкологический журнал, 2023 Purpose of the study: development of in vitro laboratory models to evaluate quality parameters and specific efficacy of dendritic cell vaccine (DCV).Material and Methods.
T. L. Nekhaeva +8 more
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Инфекция и иммунитет, 2016 Acute infectious mononucleosis is a widespread viral disease, which most often manifests in childhood. The development of acute infectious mononucleosis is accompanied by the change of the CD4+/CD8+ T-lymphocytes ratio and the increase of the virus ...
E. N. Filatova +5 more
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Медицинская иммунология, 2023 The 2019 coronavirus disease (COVID-19) pandemic has had an unprecedented impact on health and economies around the world. Direct myocardial injury and cytokine storm, leading to destabilization of preexisting plaques and accelerated formation of new ...
E. A. Safronova +2 more
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Cytotoxic T Lymphocytes in Rasmussen’s Encephalitis
Pediatric Neurology Briefs, 2002 The role of cytotoxic T lymphocytes and other mechanisms in the pathogenesis of Rasmussen’s encephalitis (RE) is reviewed at the University of Vienna, Austria, and the University of Bonn, Germany.
J Gordon Millichap
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High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity [PDF]
Frontiers in Immunology, 2021 Cytotoxic T lymphocytes (CTLs) are key players to eliminate tumorigenic or pathogen-infected cells using lytic granules (LG) and Fas ligand (FasL) pathways. Depletion of glucose leads to severely impaired cytotoxic function of CTLs. However, the impact of excessive glucose on CTL functions still remains largely unknown.
Jie Zhu +19 more
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