Results 201 to 210 of about 10,638,486 (296)

Phenotypic characterization of mucosal-associated invariant T cells in visceral leishmaniasis and HIV co-infection. [PDF]

Front Immunol
Pereira VHS, Nogueira GAF, Borges-Fernandes L, de Carvalho SH, Nogueira AMC, Araújo AL, Brito-de-Sousa JP, Rodrigues JA, Toledo JPRM, Magalhães VCR, de Carvalho JC, da Cunha LF, Coelho-Dos-Reis JGA, Teixeira-Carvalho A, Martins-Filho OA, Guimarães GMC, Peruhype-Magalhães V.   +16 more
europepmc   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Dermatomyositis and antisynthetase syndrome disease activity is associated with the expansion of peripheral GZMB⁺CD4⁺ cytotoxic T cells. [PDF]

Front Immunol
Zhang Q, Chi R, Shi G, Wan J, Chang T, Jiang Y, Wang W, Han J, Chen X, Gong F.   +9 more
europepmc   +1 more source

PARP Inhibitors plus Anlotinib as Bridging Therapy for Armored CAR‐T Cells in Ovarian Cancer Enhances Infiltration and Antitumor Efficacy

Advanced Science, EarlyView.
This study shows that a PARP inhibitor combined with anlotinib, administered as bridging therapy, preconditions the tumor microenvironment to enhance the infiltration and antitumor activity of subsequently infused CAR‐T cells across preclinical ovarian cancer models, supporting bridging therapy as a promising strategy to address limited CAR‐T cell ...
Huayi Li, Minghua Xiang, Qiuyang Xu, Jiahao Liu, Xiaofei Jiao, Wei Mu, Xiaoying Lv, Kangjia Tao, Yu Xu, Dongchen Zhou, Wenjian Gong, Danmei Yan, Yixin Hu, Sen Xu, Bingbing Zhao, Jundong Li, Yongkang Gai, Guang Hu, Li Zhu, Qinglei Gao, Yong Fang   +20 more
wiley   +1 more source

Statement of Retraction: Activation of cytotoxic T lymphocytes by self-differentiated myeloid-derived dendritic cells for killing breast cancer cells expressing folate receptor alpha protein. [PDF]

Bioengineered
europepmc   +1 more source

Comprehensive leucocyte subsets assay in healthy adults using multiparametric flowcytometry. [PDF]

Indian J Med Res
Das N, Katharia R, Pabbi S, Gupta K, Mehta P, Mishra P, Morya S.   +6 more
europepmc   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

Cancer-associated fibroblasts as architects of acquired immune-privileged-like niches in gastrointestinal cancers: lessons from ocular immune privilege and barrier biology. [PDF]

Front Immunol
Wang Y, Wang Z, Zhou F, Qiao Y, Luo Z, Wang F, Yue B, Xin D.   +7 more
europepmc   +1 more source

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source

Environmentally induced cell stiffening shapes metastatic site selection by tuning the immune vulnerability of cancer cells. [PDF]

Immunity
Elbanna YA, Tello-Lafoz M, Holland A, Zhang Y, Li C, Amin S, Wang Z, Kwak JG, Yakimov A, Vaska A, Lee E, Dada M, Vayner S, Duquette SM, Kim YH, Budhai J, Fan N, Ladewig E, Bale TA, Winer BY, Yu KKH, Massagué J, Leslie C, Lee J, Barzilai O, Manalis SR, Huse M.   +26 more
europepmc   +1 more source