Results 11 to 20 of about 235,846 (125)
Osteoimmunology: The Regulatory Roles of T Lymphocytes in Osteoporosis
Immune imbalance caused bone loss. Osteoimmunology is emerging as a new interdisciplinary field to explore the shared molecules and interactions between the skeletal and immune systems.
Wenjuan Zhang+3 more
doaj +1 more source
Immune networks: multi-tasking capabilities near saturation [PDF]
Pattern-diluted associative networks were introduced recently as models for the immune system, with nodes representing T-lymphocytes and stored patterns representing signalling protocols between T- and B-lymphocytes. It was shown earlier that in the regime of extreme pattern dilution, a system with $N_T$ T-lymphocytes can manage a number $N_B!=!\order ...
arxiv +1 more source
Optimal control of an HIV model with a trilinear antibody growth function [PDF]
We propose and study a new mathematical model of the human immunodeficiency virus (HIV). The main novelty is to consider that the antibody growth depends not only on the virus and on the antibodies concentration but also on the uninfected cells concentration.
arxiv +1 more source
CD39 is a marker of immune cells such as lymphocytes and monocytes. The CD39/CD73 pathway hydrolyzes ATP into adenosine, which has a potent immunosuppressive effect.
Alaa Elsaghir+5 more
doaj +1 more source
Vision for an Artefact-based Approach to Regulatory Requirements Engineering [PDF]
Background: Nowadays, regulatory requirements engineering (regulatory RE) faces challenges of interdisciplinary nature that cannot be tackled due to existing research gaps. Aims: We envision an approach to solve some of the challenges related to the nature and complexity of regulatory requirements, the necessity for domain knowledge, and the ...
arxiv +1 more source
Inferring HIV escape rates from multi-locus genotype data [PDF]
Cytotoxic T-lymphocytes (CTLs) recognize viral protein fragments displayed by major histocompatibility complex (MHC) molecules on the surface of virally infected cells and generate an anti-viral response that can kill the infected cells. Virus variants whose protein fragments are not efficiently presented on infected cells or whose fragments are ...
arxiv +1 more source
FEATURES OF THE PHENOTYPE OF REGULATORY T CELLS IN EARLY AND ADVANCED RHEUMATOID ARTHRITIS
Objective: to analyze the levels of CD3+, CD3+CD4+, CD3+CD8+, and CD3-CD56+ T lymphocytes, FoxP3+ regulatory T cells (Treg), and CD19+ B lymphocytes in patients with early and advanced rheumatoid arthritis (RA). Subjects and methods.
A. S. Avdeeva+5 more
doaj +1 more source
Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4
Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment.
Tobias Burkard+6 more
doaj +1 more source
Regulatory T Lymphocytes in Periodontitis: A Translational View
Periodontitis is a chronic immuno-inflammatory disease in which the disruption of the balance between host and microbiota interactions is key to the onset and progression of the disease.
Carla Alvarez+5 more
doaj +1 more source
A Re-Examination of the Foundations of Cost of Capital for Regulatory Purposes [PDF]
In regulatory proceedings, few issues are more hotly debated than the cost of capital. This article formalises the theoretical foundation of cost of capital estimation for regulatory purposes. Several common regulatory practices lack a solid foundation in the theory.
arxiv