Results 41 to 50 of about 449,121 (298)

Discrimination of human cytotoxic lymphocytes from regulatory and B-lymphocytes by orthogonal light scattering [PDF]

, 1986
Light scattering properties of human lymphocyte subpopulations selected by immunofluorescence were studied with a flow cytometer. Regulatory and B-lymphocytes showed a low orthogonal light scatter signal, whereas cytotoxic lymphocytes identified with leu-
Berkel, W. van, Greve, J., Grooth, B.G. de, Napel, C.H.H. ten, Terstappen, L.W.M.M.   +4 more
core   +4 more sources

A Guanidine-rich Regulatory Oligodeoxynucleotide Improves Type-2 Diabetes in Obese Mice by Blocking T-cell Differentiation [PDF]

, 2012
T lymphocytes exhibit pro-inflammatory or anti-inflammatory activities in obesity and diabetes, depending on their subtypes. Guanidine-rich immunosuppressive oligodeoxynucleotides (ODNs) effectively control Th1/Th2-cell counterbalance. This study reveals
Chen, Han, Cheng, Xiang, Folco, Eduardo, Kong, Wen, Liao, Yu-Hua, Libby, Peter, Liu, Juan, Shi, Guo-Ping, Sjöberg, Sara, Tang, Ting-Ting, Wang, Jing, Xia, Ni, Yan, Xin-Xin, Zhang, Hong-Jian   +13 more
core   +1 more source

A gene regulatory network armature for T lymphocyte specification [PDF]

Proceedings of the National Academy of Sciences, 2008
Choice of a T lymphoid fate by hematopoietic progenitor cells depends on sustained Notch–Delta signaling combined with tightly regulated activities of multiple transcription factors. To dissect the regulatory network connections that mediate this process, we have used high-resolution analysis of regulatory gene expression ...
Georgescu, Constantin, Longabaugh, William J. R., Scripture-Adams, Dierdre D., David-Fung, Elizabeth-Sharon, Yui, Mary A., Zarnegar, Mark A., Bolouri, Hamid, Rothenberg, Ellen V.   +7 more
openaire   +3 more sources

Immune regulation in Chandipura virus infection: characterization of CD4+ T regulatory cells from infected mice

Virology Journal, 2011
Back ground Chandipura virus produces acute infection in mice. During infection drastic reduction of CD4+, CD8+ and CD19 + cell was noticed. Depletion of lymphocytes also noticed in spleen.
Shahir Prajakta, Anukumar Balakrishnan
doaj   +1 more source

CD8+ T Lymphocytes: Crucial Players in Sjögren’s Syndrome

Frontiers in Immunology, 2021
Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease associated with damage to multiple organs and glands. The most common clinical manifestations are dry eyes, dry mouth, and enlarged salivary glands.
Huimin Zhou, Huimin Zhou, Jun Yang, Jie Tian, Shengjun Wang, Shengjun Wang   +5 more
doaj   +1 more source

Predictors of Immunosuppressive Regulatory T Lymphocytes in Healthy Women [PDF]

Journal of Cancer Epidemiology, 2012
Immunosuppressive regulatory T (Treg) cells play an important role in antitumor immunity, self-tolerance, transplantation tolerance, and attenuation of allergic response. Higher proportion of Treg cells has been observed in peripheral blood of cancer cases compared to controls.
Hampras, Shalaka S., Nesline, Mary, Wallace, Paul K., Odunsi, Kunle, Furlani, Nicholas, Davis, Warren, Moysich, Kirsten B.   +6 more
openaire   +2 more sources

Dynamic assessment of T-lymphocytes and humoral immunity in patients with acute coronary syndrome, with and without COVID-19, depending on the content of CD3⁺CD8⁺T-lymphocytes

Медицинский вестник Юга России
Objective: to evaluate the dynamics of the T- and B-cell immunity in patients with acute coronary syndrome (ACS) who have and have not had COVID-19, depending on the number of CD3+CD8+T-lymphocytes.Materials and methods: 65 men with ACS who underwent ...
E. A. Safronova, L. V. Ryabova, A. V. Zurochka, M. A. Dobrynina, E. V. Zadorina   +4 more
doaj   +1 more source

CD4+CD25+ regulatory T lymphocytes in bone marrow transplantation

Seminars in Immunology, 2006
Induction of immunological tolerance to alloantigens would be the treatment of choice to prevent graft-versus-host disease (GvHD) and allograft rejection in transplantation medicine. Organisms use a variety of mechanisms to avoid potentially deadly immunity to self-antigens.
Joffre, Olivier, van Meerwijk, Joost
openaire   +3 more sources

The Influence of the Regulatory T Lymphocytes on Atherosclerosis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2007
Atherosclerosis is complex inflammatory disease of the arterial wall, in which T lymphocytes play a significant role.1 Since the recognition that T lymphocytes are present in human atherosclerotic plaque nearly 2 decades ago,2 research has focused on the functional importance of these cells in the atherosclerotic process.
Israel, Gotsman, Rajat, Gupta, Andrew H, Lichtman   +2 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source