Results 211 to 220 of about 176,443 (228)
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Contingent Genetic Regulatory Events in T Lymphocyte Activation
Science, 1989Interaction of antigen in the proper histocompatibility context with the T lymphocyte antigen receptor leads to an orderly series of events resulting in morphologic change, proliferation, and the acquisition of immunologic function. In most T lymphocytes two signals are required to initiate this process, one supplied by the antigen receptor and the ...
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REGULATORY T-LYMPHOCYTES IN LYMPHOMAGENESIS
2020B-cell lymphomas are a heterogenous group of tumours that account for 85% of all non-Hodgkin lymphomas (NHL), tumours derived from cells of lymphoid lineage. B-lymphomas originate from various developmental stages of B lymphocytes. Classical Hodgkin’s lymphoma (cHL) also originates from B lymphocytes.
Gršković, Paula +5 more
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Regulatory factors for initial T lymphocyte lineage specification
Current Opinion in Hematology, 2007Initiation of T lymphocyte development depends on balanced regulatory inputs from multiple essential transcription factors. This review highlights contributions of E2A, hematopoietic transcription factor PU.1, growth factor independence (Gfi)-1, T cell factor (TCF)-1, and Runx factors and their interactions with the Notch pathway to promote T cell ...
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[Regulatory T lymphocytes CD4(+): current issues].
Medecine sciences : M/S, 2012Regulatory T cells (Treg) are involved in the maintenance of peripheral tolerance and in the prevention of autoimmune diseases. They are also essential to the regulation of immune responses observed in allergy, transplantation, cancers and infectious diseases. Most of Treg, called natural, differentiate in the thymus and are defined by their expression
Aurélie, Siri +2 more
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Regulatory Interactions between Virgin and Memory CD4 T Lymphocytes
Cellular Immunology, 1996Naive and memory CD4 T cells from mouse spleen, alone or in a 1:1 mixture, were tested for Con A-induced proliferation in limiting dilution cultures. Dose-response curves for naive cells were linear, but curves for memory cells were hyperbolic, suggesting that positive responses required the activation of several cells of the memory type. Mixtures (1:1)
I M, Dozmorov, R A, Miller
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The role of regulatory t lymphocytes in asthma pathogenesis
Current Allergy and Asthma Reports, 2005Several subtypes of regulatory or suppressive T cells have been described that can prevent activation of effector T cells in vitro and in vivo in animal models. Recent evidence suggests a deficit in suppressive activity of both CD4(+)CD25(+) regulatory T cells, and interleukin (IL)-10 producing regulatory T cells may play a role in development of ...
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The regulatory network that controls the differentiation of T lymphocytes
Biosystems, 2013There is a vast amount of molecular information regarding the differentiation of T lymphocytes, in particular regarding in vitro experimental treatments that modify their differentiation process. This publicly available information was used to infer the regulatory network that controls the differentiation of T lymphocytes into CD4(+) and CD8(+) cells ...
Pablo, Martínez-Sosa, Luis, Mendoza
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[Regulatory T-lymphocytes in the immune deficiency syndrome].
Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1984A 25-year-old patient presented with hypogammaglobulinemia diagnosed at the age of 7, causing recurrent infections of the gastrointestinal and bronchial tracts. He was treated with gammaglobulins and infusions of fresh human plasma. At admission he had an exacerbation of his chronic enteric symptoms.
U, Rodeck, E, Kuwert, E, Ohnhaus
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Regulatory mechanisms in cytotoxic T lymphocyte development
Cellular Immunology, 1986Brian M. Susskind +2 more
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