lHuman cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis [PDF]
Effector-memory T cells expressing Fas (Apo-1/CD95) are switched to an apoptotic program by cross-linking with Fas-ligand (FasL). Consequently, tumors that express FasL can induce apoptosis of infiltrating Fas-positive T lymphocytes and subdue any ...
Biagi, E+8 more
core
Cytotoxic Activity of Human Lymphocytes: Quantitative Analysis of T Cell and K Cell Cytotoxicity, Revealing Enzyme-Like Kinetics [PDF]
Wim P. Zeijlemaker+3 more
openalex +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Fc Receptors for IgA on Human B, and Human Non-B, Non-T Lymphocytes [PDF]
Lawrence G. Lum+4 more
openalex +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Immunophenotyping profile of infectious mononucleosis caused by Epstein-Barr virus [PDF]
Infekcijska mononukleoza uzrokovana virusom Epstein-Barr (EBV) u većine imunokompetentnih domaćina je samoograničavajuća infekcija koja se najčešće prenosi kapljicama sline zaražene osobe. U akutnoj fazi EBV zaražava epitelne stanice orofarinksa, a zatim
Mateljak, Nives
core +1 more source
Nature of T Lymphocyte Recognition of Macrophage-Associated Antigens [PDF]
David W. Thomas+2 more
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FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang+5 more
wiley +1 more source
Specific Binding of T Lymphocytes to Macrophages [PDF]
C. Rick Lyons+2 more
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source