Results 21 to 30 of about 857,009 (291)

Near-infrared imaging of adoptive immune cell therapy in breast cancer model using cell membrane labeling. [PDF]

PLoS ONE, 2014
The overall objective of this study is to non-invasively image and assess tumor targeting and retention of directly labeled T-lymphocytes following their adoptive transfer in mice.
Fatma M Youniss, Gobalakrishnan Sundaresan, Laura J Graham, Li Wang, Collin R Berry, Gajanan K Dewkar, Purnima Jose, Harry D Bear, Jamal Zweit   +8 more
doaj   +1 more source

DR-bearing T lymphocytes in thoracic duct lymph [PDF]

, 1981
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo, Albrechtson, Billing, Boyle, Colombani, Evans, Foon, Franksson, Fu, Greaves, H. Takahashi, J.C. Cicciarelli, Johnson, Kaplan, Machleder, Matell, Medawar, P.I. Terasaki, R. Billing, Starzl, Starzl, Suciu-Foca, T. Starzl, T. Yamaguchi, Terasaki, Y. Iwaki   +25 more
core   +1 more source

Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules [PDF]

, 1991
THE α1 and α2 domains of major histocompatibility complex (MHC) class I molecules function in the binding and presentation of foreign peptides to the T-cell antigen receptor and control both negative and positive selection of the T-cell repertoire ...
AM Norment, Carla J. Aldrich, CJ Aldrich, CJ Aldrich, HR MacDonald, HS Teh, HS Teh, HS Teh, IA Stroynowski, IS Trowbridge, Iwona Stroynowski, J Sprent, James Forman, JC Zuniga-Pflucker, JM Connolly, Lee Hood, M Reddehase, MA Alexander, PJ Bjorkman, R Salter, RC Budd, Robert E. Hammer, RR Zamoyska, S Marusic-Galesic, S Qin, Sharon Jones-Youngblood, UH Koszinowski, Ulrich Koszinowski, W-P Fung-Leung, WR Lie, WR Lie   +30 more
core   +1 more source

Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms

Neurobiology of Disease, 2012
Activated microglia and infiltrating lymphocytes are neuropathological hallmarks of amyotrophic lateral sclerosis (ALS), a fatal motoneuron disease.
Weihua Zhao, David R. Beers, Bing Liao, Jenny S. Henkel, Stanley H. Appel   +4 more
doaj   +1 more source

The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis [PDF]

, 2011
Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial ...
Antunes, RF, Dumitriu, IE, Kaski, JC
core   +3 more sources

ANTI-APOPTOTIC EFFECT OF CD95 RECEPTOR IN NA VE CD8+ T-LYMPHOCYTES IN CHILDREN WITH ACUTE INFECTIOUS MONONUCLEOSIS

Инфекция и иммунитет, 2016
Acute infectious mononucleosis is a widespread viral disease, which most often manifests in childhood. The development of acute infectious mononucleosis is accompanied by the change of the CD4+/CD8+ T-lymphocytes ratio and the increase of the virus ...
E. N. Filatova, E. V. Anisenkova, N. B. Presnyakova, T. D. Sycheva, E. A. Kulova, O. V. Utkin   +5 more
doaj   +1 more source

Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands [PDF]

, 1992
Cytomegalovirus (CMV), similar to other members of the Herpesviridae family, can establish both persistent and latent infections. Each of the CMVs that are found in many animal species replicates in the salivary gland, and oral secretion represents a ...
Jonjic, Stipan, Koszinowski, Ulrich H., Lucin, Pero, Pavic, Ivica, Polic, Bojan   +4 more
core   +2 more sources

Ca2+ Microdomains in T-Lymphocytes

Frontiers in Oncology, 2017
Early Ca2+ signaling is characterized by occurrence of Ca2+ microdomains formed by opening of single or clusters of Ca2+ channels, thereby initiating first signaling and subsequently activating global Ca2+ signaling mechanisms. However, only few data are
Andreas H. Guse, Insa M. A. Wolf
doaj   +1 more source

Immunology and immunotherapy in the complex treatment of malignant tumors

Медицинский совет, 2021
Immuno-oncology is a rapidly developing field in medicine. Drug combination therapies have already been studied in many clinical trials of different types of tumours. In recent years, a checkpoint inhibition therapy with monoclonal antibodies that target
V. F. Semiglazov, A. I. Tseluiko, I. A. Baldueva, T. L. Nekhaeva, A. S. Artemyeva, A. G. Kudaybergenova, S. A. Protsenko, A. V. Novik, V. V. Semiglazov, R. V. Donskikh, T. Yu. Semiglazova, R. S. Pesotskiy, V. S. Apollonova, P. V. Krivorotko, A. M. Belyaev   +14 more
doaj   +1 more source

Functional characterization of infiltrating T lymphocytes in human hepatic allografts [PDF]

, 1986
We have employed recently developed techniques in T-cell culturing to study the nature and function of infiltrating hepatic allograft T cells. Using the rationale that intragraft T cells are activated during cell mediated damage to the allograft, we were
Adriana Zeevi, Ascher, Bernard, Bono, Brodsky, Brodsky, Brodsky, Burdick, Burdick, Cerilli, Depper, Fiche, Goyert, HancocK, Harty, Hayry, Hoshinaga, Houssin, Iwatsuki, Iwatsuki, Iwatsuki, Jake Demetris, Jeannet, John J. Fung, Kim, Kolbeck, Lampson, Marboe, Mayer, Moreau, Palacios, Paradis, Pober, Rene J. Duquesnoy, Roberts, Shaw, Shunzaburo Iwatsuki, Snover, Spits, Starzl, Steinmuller, Stelzer, Strassman, Thomas E. Starzl, Thompson, Thorley-Lawson, Tilney, van Es, Weintraub, Zeevi, Zeevi, Zeevi, Zeevi, Zeevi   +53 more
core   +1 more source