II. Detection of an antigen on resting T cells down-regulated after activation [PDF]
, 1987 The expression of an antigen on porcine T lymphocytes detected by murine monoclonal antibody (mAb) 8/1 was investigated by functional studies and dual-parameter immunofluorescence.
Saalmüller, Armin +4 more
core +1 more source
Cytotoxic T Lymphocytes in Rasmussen’s Encephalitis
Pediatric Neurology Briefs, 2002 The role of cytotoxic T lymphocytes and other mechanisms in the pathogenesis of Rasmussen’s encephalitis (RE) is reviewed at the University of Vienna, Austria, and the University of Bonn, Germany.
J Gordon Millichap
doaj +1 more source
Classification of T lymphocyte motility behaviors using a machine learning approach.
PLoS Computational Biology, 2023 T lymphocytes migrate into organs and interact with local cells to perform their functions. How human T lymphocytes communicate with organ-specific cells and participate in pathobiological processes remains unresolved. Brain infiltration of T lymphocytes
Yves Carpentier Solorio +5 more
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A nongenomic mechanism for progesterone-mediated immunosuppression: Inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes [PDF]
, 1998 The mechanism by which progesterone causes localized suppression of the immune response during pregnancy has remained elusive. Using human T lymphocytes and T cell lines, we show that progesterone, at concentrations found in the placenta, rapidly and ...
Christopher M. Fanger +23 more
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European Journal of Medical Research, 2017 Background T lymphocytes exert important homeostatic functions in the healthy intestinal mucosa, whereas in case of colorectal cancer (CRC), infiltration of T lymphocytes into the tumor is crucial for an effective anti-tumor immune response.
Ann-Britt Löfroos +3 more
doaj +1 more source
Protection against lethal cytomegalovirus infection by a recombinant vaccine containing a single nonameric T-cell epitope [PDF]
, 1991 The regulatory immediate-early (IE) protein pp89 of murine cytomegalovirus induces CD8+ T lymphocytes that protect against lethal murine cytomegalovirus infection.
Ulrich +12 more
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CD39 molecule: a negative regulator expressed on T cells in patients with lung adenocarcinoma
Archives of Medical Science, 2023 Introduction The function of cytotoxic cells may be impacted by CD39 expression on CD8-positive T lymphocytes, leading to an imbalance in tumor immunity.
Lu Tang, Hao Jin
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Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection. [PDF]
, 2003 CXCR4 expression on feline peripheral blood mononuclear cells (PBMC) was analyzed. While monocytes and B lymphocytes expressed CXCR4, no CXCR4 was detected on T lymphocytes, in stark contrast to the expression pattern on T lymphocytes from humans.
Hosie, M.J., Willett, B.J., Cannon, C.A.
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Generating CAR T cells from tumor-infiltrating lymphocytes
Therapeutic Advances in Vaccines and Immunotherapy, 2021 Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma.
Jane K. Mills +8 more
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