Results 21 to 30 of about 664,181 (259)

ANTI-APOPTOTIC EFFECT OF CD95 RECEPTOR IN NA VE CD8+ T-LYMPHOCYTES IN CHILDREN WITH ACUTE INFECTIOUS MONONUCLEOSIS

open access: yesИнфекция и иммунитет, 2016
Acute infectious mononucleosis is a widespread viral disease, which most often manifests in childhood. The development of acute infectious mononucleosis is accompanied by the change of the CD4+/CD8+ T-lymphocytes ratio and the increase of the virus ...
E. N. Filatova   +5 more
doaj   +1 more source

Cytotoxic T Lymphocytes in Rasmussen’s Encephalitis

open access: yesPediatric Neurology Briefs, 2002
The role of cytotoxic T lymphocytes and other mechanisms in the pathogenesis of Rasmussen’s encephalitis (RE) is reviewed at the University of Vienna, Austria, and the University of Bonn, Germany.
J Gordon Millichap
doaj   +1 more source

Classification of T lymphocyte motility behaviors using a machine learning approach.

open access: yesPLoS Computational Biology, 2023
T lymphocytes migrate into organs and interact with local cells to perform their functions. How human T lymphocytes communicate with organ-specific cells and participate in pathobiological processes remains unresolved. Brain infiltration of T lymphocytes
Yves Carpentier Solorio   +5 more
doaj   +1 more source

Colorectal cancer-infiltrating T lymphocytes display a distinct chemokine receptor expression profile

open access: yesEuropean Journal of Medical Research, 2017
Background T lymphocytes exert important homeostatic functions in the healthy intestinal mucosa, whereas in case of colorectal cancer (CRC), infiltration of T lymphocytes into the tumor is crucial for an effective anti-tumor immune response.
Ann-Britt Löfroos   +3 more
doaj   +1 more source

CD39 molecule: a negative regulator expressed on T cells in patients with lung adenocarcinoma

open access: yesArchives of Medical Science, 2023
Introduction The function of cytotoxic cells may be impacted by CD39 expression on CD8-positive T lymphocytes, leading to an imbalance in tumor immunity.
Lu Tang, Hao Jin
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean   +7 more
wiley   +1 more source

Generating CAR T cells from tumor-infiltrating lymphocytes

open access: yesTherapeutic Advances in Vaccines and Immunotherapy, 2021
Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma.
Jane K. Mills   +8 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

FEATURES OF THE PHENOTYPE OF REGULATORY T CELLS IN EARLY AND ADVANCED RHEUMATOID ARTHRITIS

open access: yesНаучно-практическая ревматология, 2018
Objective: to analyze the levels of CD3+, CD3+CD4+, CD3+CD8+, and CD3-CD56+ T lymphocytes, FoxP3+ regulatory T cells (Treg), and CD19+ B lymphocytes in patients with early and advanced rheumatoid arthritis (RA). Subjects and methods.
A. S. Avdeeva   +5 more
doaj   +1 more source

T Lymphocytes, Multi-Omic Interactions and Bronchopulmonary Dysplasia

open access: yesFrontiers in Pediatrics, 2021
Bronchopulmonary dysplasia (BPD) remains a significant clinical challenge in neonatal medicine. BPD is clearly a multifactorial disease with numerous antenatal and postnatal components influencing lung development.
Gergely Toldi   +5 more
doaj   +1 more source

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