Results 21 to 30 of about 11,626,734 (290)

Production of CD87 Antigen-Specific CAR-T Lymphocytes and Assessment of Their In Vitro Functional Activity

open access: yesКлиническая онкогематология, 2022
Aim. To generate anti-CD87 CAR-T lymphocytes and to assess their in vitro functional activity. Materials & Methods. Т-lymphocytes isolated from healthy donor peripheral blood were transduced with the anti-CD87-CAR, T2A, and FusionRed gene coding ...
M. V. Neklesova   +5 more
doaj   +1 more source

T Lymphocytes Are Not Immune [PDF]

open access: yesMolecular Therapy, 2013
Administration of genetically modified T lymphocytes to cancer patients has increased exponentially over the past 15 years, and these cells have been given to many hundreds of patients. These studies have often used retroviral vectors, and, in sharp contrast to clinical trials using hematopoietic stem cells as targets, gene-modified T cells have not ...
openaire   +2 more sources

Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms

open access: yesNeurobiology of Disease, 2012
Activated microglia and infiltrating lymphocytes are neuropathological hallmarks of amyotrophic lateral sclerosis (ALS), a fatal motoneuron disease.
Weihua Zhao   +4 more
doaj   +1 more source

CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity [PDF]

open access: yes, 1987
We have shown in a murine model system for acute, lethal cytomegalovirus (CMV) disease in the immunocompromised natural host that control of virus multiplication in tissues, protection from virus-caused tissue destruction, and survival are mediated by ...
Reddehase, Matthias J.   +4 more
core   +1 more source

Near-infrared imaging of adoptive immune cell therapy in breast cancer model using cell membrane labeling. [PDF]

open access: yesPLoS ONE, 2014
The overall objective of this study is to non-invasively image and assess tumor targeting and retention of directly labeled T-lymphocytes following their adoptive transfer in mice.
Fatma M Youniss   +8 more
doaj   +1 more source

Innate-like T lymphocytes in chronic liver disease

open access: yesFrontiers in Immunology, 2023
In addition to its metabolic activities, it is now clear that the liver hosts a number of diverse immune cell types that control tissue homeostasis.
Maria Papanastasatou   +1 more
doaj   +1 more source

Lymphocytes [PDF]

open access: yes, 2019
Lymphocytes have been the main research object of the medic and toxicological sciences for the last six decades. In addition to important roles, they ply m the immune system, lymphocytes have been the primary test material often employed m pure research ...
İla, Hasan Basri
core   +1 more source

IL-17-Producing Regulatory T lymphocytes – Suppressors or Effectors?

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2023
Regulatory T (Treg) lymphocytes are a T helper population that controls the intensity of the immune response and maintains immune tolerance by selectively suppressing the activity of effector T lymphocytes.
E. M. Kuklina, N. S. Glebezdina
doaj   +1 more source

Ca2+ Microdomains in T-Lymphocytes

open access: yesFrontiers in Oncology, 2017
Early Ca2+ signaling is characterized by occurrence of Ca2+ microdomains formed by opening of single or clusters of Ca2+ channels, thereby initiating first signaling and subsequently activating global Ca2+ signaling mechanisms. However, only few data are
Andreas H. Guse, Insa M. A. Wolf
doaj   +1 more source

ANTI-APOPTOTIC EFFECT OF CD95 RECEPTOR IN NA VE CD8+ T-LYMPHOCYTES IN CHILDREN WITH ACUTE INFECTIOUS MONONUCLEOSIS

open access: yesИнфекция и иммунитет, 2016
Acute infectious mononucleosis is a widespread viral disease, which most often manifests in childhood. The development of acute infectious mononucleosis is accompanied by the change of the CD4+/CD8+ T-lymphocytes ratio and the increase of the virus ...
E. N. Filatova   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy