Results 41 to 50 of about 13,171,622 (345)

Regulatory role of CD8+ T lymphocytes in bone marrow eosinophilopoiesis [PDF]

, 2006
Background There is a growing body of evidence to suggest that CD8+ T lymphocytes contribute to local allergen-induced eosinophilic inflammation. Since bone marrow (BM) responses are intricately involved in the induction of airway eosinophilia, we ...
Madeleine Rådinger, Svetlana Sergejeva, Anna-Karin Johansson, Carina Malmhäll, Apostolos Bossios, Margareta Sjöstrand, James J Lee, Jan Lötvall   +7 more
core   +1 more source

Pathogen-reactive T helper cell analysis in the pig [PDF]

, 2017
There is growing interest in studying host-pathogen interactions in human-relevant large animal models such as the pig. Despite the progress in developing immunological reagents for porcine T cell research, there is an urgent need to directly assess ...
Agnone, Araújo, Bacher, Bacher, Bacher, Bacher, Bacher, Bailey, Barman, Betson, Brooker, Buchholz, Charerntantanakul, Chattopadhyay, Chattopadhyay, Christopher-Hennings, Cohen, Dawson, Ebner, Espinosa, Frentsch, Geiger, Gerner, Gerner, Ghannoum, Gottschalk, Guilloteau, Gómez-Gascón, Henderson, Hewitson, Hoeflinger, Jeffrey, Kirchhoff, Koguchi, Koh, Koinig, Käser, Käser, Lecours, Lee, Li, Lunney, Mair, Meier, Meurens, Molinari, Neller, Reutner, Reutner, Rothkötter, Rubtsova, Saalmüller, Schulze, Seder, Seele, Seele, Takamatsu, Talker, Talker, Tenter, Thamsborg, Tramsen, Vlaminck, Yellin   +63 more
core   +6 more sources

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo [PDF]

, 2007
We treated 10 children with X-linked SCID (SCID-X1) using gammaretrovirus-mediated gene transfer. Those with sufficient follow-up were found to have recovered substantial immunity in the absence of any serious adverse events up to 5 years after treatment.
Kerstin Schwarzwaelder, Steven J. Howe, Manfred Schmidt, Martijn H. Brugman, Annette Deichmann, Hanno Glimm, Sonja Schmidt, Claudia Prinz, Manuela Wissler, Douglas J.S. King, Fang Zhang, Kathryn L. Parsley, Kimberly C. Gilmour, Joanna Sinclair, Jinhua Bayford, Rachel Peraj, Karin Pike-Overzet, Frank J.T. Staal, Dick de Ridder, Christine Kinnon, Ulrich Abel, Gerard Wagemaker, H. Bobby Gaspar, Adrian J. Thrasher, Christof von Kalle, Cavazzana-Calvo, Gaspar, Hacein-Bey-Abina, Aiuti, Aiuti, Gaspar, Ott, Hacein-Bey-Abina, Li, Kustikova, Modlich, Montini, Mitchell, Schröder, Wu, Bushman, Schmidt, Schmidt, Hematti, Laufs, Suzuki, Bartholomew, Recchia, Calmels, Hoeben, Palmer, Xu, Dik, Ge   +53 more
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

CD39 molecule: a negative regulator expressed on T cells in patients with lung adenocarcinoma

Archives of Medical Science, 2023
Introduction The function of cytotoxic cells may be impacted by CD39 expression on CD8-positive T lymphocytes, leading to an imbalance in tumor immunity.
Lu Tang, Hao Jin
doaj   +1 more source

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.

Cell, 2018
Cancer immunotherapies have shown substantial clinical activity for a subset of patients with epithelial cancers. Still, technological platforms to study cancer T-cell interactions for individual patients and understand determinants of responsiveness are
K. Dijkstra, C. Cattaneo, F. Weeber, M. Chalabi, J. van de Haar, Lorenzo F. Fanchi, M. Slagter, D. L. van der Velden, S. Kaing, S. Kelderman, Nienke van Rooij, M. V. van Leerdam, A. Depla, E. Smit, K. Hartemink, R. de Groot, M. Wolkers, Norman Sachs, P. Snaebjornsson, K. Monkhorst, J. Haanen, H. Clevers, T. Schumacher, E. Voest   +23 more
semanticscholar   +1 more source

The dendritic cell niche in chronic obstructive pulmonary disease. [PDF]

, 2012
The pulmonary innate immune system is heavily implicated in the perpetual airway inflammation and impaired host defense characterizing Chronic Obstructive Pulmonary Disease (COPD).
Haczku, Angela
core   +3 more sources

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

FEATURES OF THE PHENOTYPE OF REGULATORY T CELLS IN EARLY AND ADVANCED RHEUMATOID ARTHRITIS

Научно-практическая ревматология, 2018
Objective: to analyze the levels of CD3+, CD3+CD4+, CD3+CD8+, and CD3-CD56+ T lymphocytes, FoxP3+ regulatory T cells (Treg), and CD19+ B lymphocytes in patients with early and advanced rheumatoid arthritis (RA). Subjects and methods.
A. S. Avdeeva, Yu. P. Rubtsov, T. V. Popkova, D. T. Dyikanov, A. P. Aleksankin, E. L. Nasonov   +5 more
doaj   +1 more source

Membrane Surface Nanostructures and Adhesion Property of T Lymphocytes Exploited by AFM [PDF]

, 2009
The activation of T lymphocytes plays a very important role in T-cell-mediated immune response. Though there are many related literatures, the changes of membrane surface nanostructures and adhesion property of T lymphocytes at different activation ...
Yangzhe Wu, Hongsong Lu, Jiye Cai, Xianhui He, Yi Hu, HongXia Zhao, Xiaoping Wang, X Zhang, G Binnig, Z Wang, SR Jian, HJ Butt, K Waar, SE Cross, WA Lam, P Parot, A Franco-Obregon, EP Wojcikiewicz, X Zhang, X Zhang, WF Heinz, S Strasser, WR Bowen, E Canetta, V Lulevich, EP Wojcikiewicz, W Fritzsche, W Fritzsche, GA Burks, JK Burkhardt, S Dadsetan, S Feske, PA Negulescu, L Xu   +33 more
core   +2 more sources