Results 41 to 50 of about 12,877,653 (356)

Colorectal cancer-infiltrating T lymphocytes display a distinct chemokine receptor expression profile

open access: yesEuropean Journal of Medical Research, 2017
Background T lymphocytes exert important homeostatic functions in the healthy intestinal mucosa, whereas in case of colorectal cancer (CRC), infiltration of T lymphocytes into the tumor is crucial for an effective anti-tumor immune response.
Ann-Britt Löfroos   +3 more
doaj   +1 more source

B lymphocytes secrete antigen-presenting vesicles

open access: yesJournal of Experimental Medicine, 1996
Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II- enriched compartment), that harbors newly synthesized MHC class II molecules in transit to the plasma membrane. MIICs have a
G. Raposo   +6 more
semanticscholar   +1 more source

Near-infrared imaging of adoptive immune cell therapy in breast cancer model using cell membrane labeling. [PDF]

open access: yesPLoS ONE, 2014
The overall objective of this study is to non-invasively image and assess tumor targeting and retention of directly labeled T-lymphocytes following their adoptive transfer in mice.
Fatma M Youniss   +8 more
doaj   +1 more source

Innate-like T lymphocytes in chronic liver disease

open access: yesFrontiers in Immunology, 2023
In addition to its metabolic activities, it is now clear that the liver hosts a number of diverse immune cell types that control tissue homeostasis.
Maria Papanastasatou   +1 more
doaj   +1 more source

Role of T Lymphocytes in Glioma Immune Microenvironment: Two Sides of a Coin. [PDF]

open access: yesBiology (Basel)
Glioma is known for its immunosuppressive microenvironment, which makes it challenging to target through immunotherapies. Immune cells like macrophages, microglia, myeloid-derived suppressor cells, and T lymphocytes are known to infiltrate the glioma ...
Noor L, Upadhyay A, Joshi V.
europepmc   +2 more sources

Tertiary Lymphoid Structures and Cancer Prognosis (Brief Review)

open access: yesКреативная хирургия и онкология, 2020
This brief review is devoted to the role of tertiary lymphoid structures in oncological processes. A number of research studies carried out over the past ten years have shed light on the functions of such structures in various diseases, as well as their ...
R. A. Rustamkhanov   +2 more
doaj   +1 more source

A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma [PDF]

open access: yesarXiv, 2021
The infiltration of T-lymphocytes in the stroma and tumour is an indication of an effective immune response against the tumour, resulting in better survival. In this study, our aim is to explore the prognostic significance of tumour-associated stroma infiltrating lymphocytes (TASILs) in head and neck squamous cell carcinoma (HNSCC) through an AI based ...
arxiv  

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Classification of T lymphocyte motility behaviors using a machine learning approach.

open access: yesPLoS Computational Biology, 2023
T lymphocytes migrate into organs and interact with local cells to perform their functions. How human T lymphocytes communicate with organ-specific cells and participate in pathobiological processes remains unresolved. Brain infiltration of T lymphocytes
Yves Carpentier Solorio   +5 more
doaj   +1 more source

Activation of lymphocytes [PDF]

open access: yesJournal of Clinical Pathology, 1967
The technique involved in studying the activation of lymphocytes in the resting form, and their recognition as dividing and functional cells was studied, using phase contrast and agar as well as fluid culture. Standardization of technical methods was found to be essential, and the effect of variables was studied.
R. J. V. Pulvertaft, Isobel Pulvertaft
openaire   +2 more sources

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