Results 51 to 60 of about 12,260,183 (375)
Local CD4+, CD8+ and CD56+ reactions to lung cancer in regard to pathohistological type and clinical stage [PDF]
Medicinski Glasnik, 2011 Aim To determinate the difference of abundance of CD4+, CD8+ and CD56+ bronchoalveolar luid’s lymphocytes and their subpopulations between non- and small cell lung cancer.
Edin Jusufovic +8 more
doaj
B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes
Frontiers in Immunology, 2019 Previous studies indicate that B-lymphocytes play a key role activating diabetogenic T-lymphocytes during the development of autoimmune diabetes. Recently, two transgenic NOD mouse models were generated: the NOD-PerIg and the 116C-NOD mice.
Leire Egia-Mendikute +14 more
doaj +1 more source
Generating CAR T cells from tumor-infiltrating lymphocytes
Therapeutic Advances in Vaccines and Immunotherapy, 2021 Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma.
Jane K. Mills +8 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Frontiers in Immunology, 2021 T-bet, a T-box family member, is a transcription factor essential for the differentiation of naive CD4+ T cells into Th1 cells that are involved in both innate and adaptive immune responses.
Hongfei Tian +8 more
doaj +1 more source
Characterization of serotonin transporter expression in human T lymphocytes [PDF]
, 2014 Serotonin transporter (SERT) expression has been demonstrated in human lymphocytes, including B lymphocytes, NK cells and other immune cells. However, discussion remains on whether human T lymphocytes express SERT. Given the potentially important role of
De Spiegelaere, Ward +5 more
core
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
T cells responding to Trypanosoma cruzi detected by membrane TNF‐α and CD154 in chagasic patients
Immunity, Inflammation and Disease, 2018 Introduction Chagas disease is a parasitic infection whose pathogenesis is related to parasite persistence and a dysfunctional cellular immune response.
Juan G. Ripoll +7 more
doaj +1 more source
Role of early viral surface antigens in cellular immune response to vaccinia virus [PDF]
, 1976 Infection of mice with the vaccinia virus strain WR, Elstree or DIs, a conditional lethal mutant of vaccinia virus, resulted in the generation of vaccinia virus-specific sensitized cytolytic T lymphocytes (CTL).
Ertl, H., Koszinowski, Ulrich H.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source