Results 61 to 70 of about 12,877,653 (356)
Local CD4+, CD8+ and CD56+ reactions to lung cancer in regard to pathohistological type and clinical stage [PDF]
Aim To determinate the difference of abundance of CD4+, CD8+ and CD56+ bronchoalveolar luid’s lymphocytes and their subpopulations between non- and small cell lung cancer.
Edin Jusufovic+8 more
doaj
Histological examination of the palatine tonsils in chronic tonsillitis
The article is devoted to the problem of chronic tonsillitis. The aim of the study was to assess changes in the morphofunctional state of the palatine tonsils in chronic inflammation. The study presents comparative data of immunohistochemical examination
V. T. Pal’chun+3 more
doaj +1 more source
Generating CAR T cells from tumor-infiltrating lymphocytes
Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma.
Jane K. Mills+8 more
doaj +1 more source
IL-17-Producing Regulatory T lymphocytes – Suppressors or Effectors?
Regulatory T (Treg) lymphocytes are a T helper population that controls the intensity of the immune response and maintains immune tolerance by selectively suppressing the activity of effector T lymphocytes.
E. M. Kuklina, N. S. Glebezdina
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Anti-inflammatory therapy in chronic obstructive pulmonary disease: present and future
Today chronic obstructive pulmonary disease is a major economic and social challenge and the only disease causing an ever-increasing number of fatalities [4, 5]. According to a number of recently completed studies, the prevalence of chronic lung diseases
S. N. Avdeev
doaj +1 more source
Reduction of CD8+ T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate
Objective: To evaluate the influence of dimethyl fumarate (DMF, Tecfidera) treatment of multiple sclerosis (MS) on leukocyte and lymphocyte subsets. Methods: Peripheral blood leukocyte and lymphocyte subsets, including CD3+, CD4+, and CD8+ T cells; CD19+
Collin M. Spencer+4 more
semanticscholar +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
CD39 molecule: a negative regulator expressed on T cells in patients with lung adenocarcinoma
Introduction The function of cytotoxic cells may be impacted by CD39 expression on CD8-positive T lymphocytes, leading to an imbalance in tumor immunity.
Lu Tang, Hao Jin
doaj +1 more source
Metabolic regulation of T lymphocytes.
T cell activation leads to dramatic shifts in cell metabolism to protect against pathogens and to orchestrate the action of other immune cells. Quiescent T cells require predominantly ATP-generating processes, whereas proliferating effector T cells ...
Nancie J. MacIver+2 more
semanticscholar +1 more source