Results 81 to 90 of about 664,181 (259)

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

Advanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen, Nina Li, Meiyan Zou, Zihao Zhou, Rongwei Xu, Weiyao Feng, Xinyuan Zhao, Li Cui   +7 more
wiley   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source

Nocturnal Intraocular Pressure Monitoring With a Soft Contact Lens Sensor for Glaucoma Management

Advanced Materials, EarlyView.
A soft contact lens sensor enables continuous, noninvasive monitoring of nocturnal intraocular pressure (IOP) under closed‐eye sleep conditions. By integrating a highly compliant inductive–capacitive circuit onto a commercial lens, the device achieves record sensitivity and stable performance.
Yumin Dai, Tristan Michael Long, Oluwabunmi T. Oladele, Youngoh Lee, Feiyang Li, Ziheng Wang, Yeonji Oh, Junsang Lee, Taewoong Park, Tianhao Yu, Seokkyoon Hong, Kyeonghee Lim, Jinheon Jeong, Dawn Meyer Schneider, Hyerim Ra, Bryan W. Boudouris, Gillian C. Shaw, Shin Ae Park, Pete S. Kollbaum, Chi Hwan Lee   +19 more
wiley   +1 more source

Cytotoxic CD4+ T cells: origin, biological functions, diseases and therapeutic targets

Signal Transduction and Targeted Therapy
Cytotoxic CD4+ T lymphocytes are a unique subset of CD4+ T cells characterized by their cytokine secretion and cytolytic activity. Unlike traditional CD4+ helper T cells, cytotoxic CD4+ T lymphocytes exhibit similar cytotoxicity to that of CD8+ T cells ...
Longyong Lai, Shuan Ran, Yuan Li, Jikai Cui, Xi Zhang, Jizhang Yu, Yanqiang Zou, Cheng Zhou, Jiahong Xia, Jie Wu   +9 more
doaj   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source

Role of T Lymphocytes in Glioma Immune Microenvironment: Two Sides of a Coin

Biology
Glioma is known for its immunosuppressive microenvironment, which makes it challenging to target through immunotherapies. Immune cells like macrophages, microglia, myeloid-derived suppressor cells, and T lymphocytes are known to infiltrate the glioma ...
Laiba Noor, Arun Upadhyay, Vibhuti Joshi
doaj   +1 more source

Photoactivable Surfactant Design for In Situ Stabilization of Hydrogel Bioelectronics

Advanced Materials, EarlyView.
Photoactivable surfactant additive enables in situ stabilization of hydrogel bioelectronics. ABSTRACT Conductive polymer hydrogels offer unique advantages for soft, stretchable biointerfaces by combining tissue‐like mechanics with high ionic conductivity.
Seungyeon Lee, Donggyun Lee, Soo‐Hwan Lee, Yuri Lee, Jooyeun Chong, Gunho Chang, Hyunjun Kim, Aejin Kim, Kyung Su Kim, Jahyun Koo, Hyojin Lee, Jiheong Kang   +11 more
wiley   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source