Results 71 to 80 of about 12,391,565 (386)
The role of regulatory T cells in the modulation of anti-tumor immune response [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2013 It has been shown that the loss of regulatory function by deple + Regulatory T cells (Treg) represent a subset of CD4 T cells whose function is to suppress immune responses.
Radosavljević Gordana D. +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
T Lymphocytes, Multi-Omic Interactions and Bronchopulmonary Dysplasia
Frontiers in Pediatrics, 2021 Bronchopulmonary dysplasia (BPD) remains a significant clinical challenge in neonatal medicine. BPD is clearly a multifactorial disease with numerous antenatal and postnatal components influencing lung development.
Gergely Toldi +5 more
doaj +1 more source
Journal of Allergy and Clinical Immunology, 2003 The fundamental task of the immune system is to defend "self" from "nonself." Lymphocytes are the primary cells of the immune system that developed one of the most sophisticated and comprehensive defense mechanisms in the biological system. T cells play a central role in orchestrating the immune response.
Rafeul, Alam, Magdalena, Gorska
openaire +2 more sources
HLA-Associated viral mutations are common in human immunodeficiency virus type 1 elite controllers [PDF]
, 2009 Elite controllers (EC) of human immunodeficiency virus type 1 (HTV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8+ T lymphocytes are believed to play a crucial role in viral containment ...
Block, B. L. +10 more
core +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
FUNCTIONAL AORTIC STIFFNESS:ROLE OF CD4+ T LYMPHOCYTES
Frontiers in Physiology, 2015 The immune system is suggested to be essential in vascular remodeling and stiffening. To study the dependence upon lymphocytes in vascular stiffening, we compared an angiotensin II-model of vascular stiffening in normal C57BL/6J mice with lymphocyte ...
Beenish A. Majeed +5 more
doaj +1 more source
Journal of Neuroinflammation, 2022 Background Interleukin-27 (IL-27) can trigger both pro- and anti-inflammatory responses. This cytokine is elevated in the central nervous system (CNS) of multiple sclerosis (MS) patients, but how it influences neuroinflammatory processes remains unclear.
Florent Lemaître +13 more
doaj +1 more source
Reduction of CD8+ T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate
Neurology: Neuroimmunology & Neuroinflammation, 2015 Objective: To evaluate the influence of dimethyl fumarate (DMF, Tecfidera) treatment of multiple sclerosis (MS) on leukocyte and lymphocyte subsets. Methods: Peripheral blood leukocyte and lymphocyte subsets, including CD3+, CD4+, and CD8+ T cells; CD19+
Collin M. Spencer +4 more
semanticscholar +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source