Results 71 to 80 of about 12,985,045 (397)

IL-17-Producing Regulatory T lymphocytes – Suppressors or Effectors?

Учёные записки Казанского университета: Серия Естественные науки, 2023
Regulatory T (Treg) lymphocytes are a T helper population that controls the intensity of the immune response and maintains immune tolerance by selectively suppressing the activity of effector T lymphocytes.
E. M. Kuklina, N. S. Glebezdina
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Functional characterization of infiltrating T lymphocytes in human hepatic allografts [PDF]

, 1986
We have employed recently developed techniques in T-cell culturing to study the nature and function of infiltrating hepatic allograft T cells. Using the rationale that intragraft T cells are activated during cell mediated damage to the allograft, we were
Adriana Zeevi, Ascher, Bernard, Bono, Brodsky, Brodsky, Brodsky, Burdick, Burdick, Cerilli, Depper, Fiche, Goyert, HancocK, Harty, Hayry, Hoshinaga, Houssin, Iwatsuki, Iwatsuki, Iwatsuki, Jake Demetris, Jeannet, John J. Fung, Kim, Kolbeck, Lampson, Marboe, Mayer, Moreau, Palacios, Paradis, Pober, Rene J. Duquesnoy, Roberts, Shaw, Shunzaburo Iwatsuki, Snover, Spits, Starzl, Steinmuller, Stelzer, Strassman, Thomas E. Starzl, Thompson, Thorley-Lawson, Tilney, van Es, Weintraub, Zeevi, Zeevi, Zeevi, Zeevi, Zeevi   +53 more
core   +1 more source

Visceral obesity and cardiometabolic risk: features of hormonal and immune regulation

Ожирение и метаболизм, 2017
The issue of the prognostic value of obesity in the development of cardiovascular diseases still remains open. Different input of visceral and subcutaneous adipose tissue in the formation of cardiometabolic risk is highlighted in many research works.
Irina V. Kologrivova, Irina V. Vinnitskaya, Olga A. Koshelskaya, Tatiana E. Suslova   +3 more
doaj   +1 more source

Reduction of CD8+ T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate

Neurology: Neuroimmunology & Neuroinflammation, 2015
Objective: To evaluate the influence of dimethyl fumarate (DMF, Tecfidera) treatment of multiple sclerosis (MS) on leukocyte and lymphocyte subsets. Methods: Peripheral blood leukocyte and lymphocyte subsets, including CD3+, CD4+, and CD8+ T cells; CD19+
Collin M. Spencer, E. Crabtree‐Hartman, K. Lehmann-Horn, B. Cree, S. Zamvil   +4 more
semanticscholar   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Characterization of serotonin transporter expression in human T lymphocytes [PDF]

, 2014
Serotonin transporter (SERT) expression has been demonstrated in human lymphocytes, including B lymphocytes, NK cells and other immune cells. However, discussion remains on whether human T lymphocytes express SERT. Given the potentially important role of
De Spiegelaere, Ward, Deforce, Dieter, Gobin, Veerle, Kiselinova, Maja, Van Steendam, Katleen, Vandekerckhove, Linos   +5 more
core  

SPONTANEOUS-RECOVERY OF RATS FROM EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IS DEPENDENT ON REGULATION OF THE IMMUNE-SYSTEM BY ENDOGENOUS ADRENAL CORTICOSTEROIDS [PDF]

, 1989
Experimental allergic encephalomyelitis (EAE) ' is a paralytic disease that can be induced in a number of animal species by evoking immune responses to antigens in central nervous system (CNS) myelin, and has been studied as a model for multiple ...
Antoni, FA, MacPhee, IA, Mason, DW
core   +3 more sources

CD39 molecule: a negative regulator expressed on T cells in patients with lung adenocarcinoma

Archives of Medical Science, 2023
Introduction The function of cytotoxic cells may be impacted by CD39 expression on CD8-positive T lymphocytes, leading to an imbalance in tumor immunity.
Lu Tang, Hao Jin
doaj   +1 more source

Metabolic regulation of T lymphocytes.

Annual Review of Immunology, 2013
T cell activation leads to dramatic shifts in cell metabolism to protect against pathogens and to orchestrate the action of other immune cells. Quiescent T cells require predominantly ATP-generating processes, whereas proliferating effector T cells ...
Nancie J. MacIver, Ryan D. Michalek, J. Rathmell   +2 more
semanticscholar   +1 more source