Results 201 to 210 of about 681,261 (380)

Safety and Efficacy of Long‐Term Treatment of Type 1 Plasminogen Deficient Patients With Intravenous Plasminogen Replacement Therapy

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Type 1 plasminogen deficiency (PLGD‐1), or hypoplasminogenaemia, is an ultra‐rare autosomal‐recessive disorder characterised by fibrin‐rich lesions on mucous membranes, often leading to serious complications if left untreated. Prior treatments have shown limited and inconsistent success, but IV PLG concentrate (Ryplazim) offers a ...
Amy D. Shapiro   +7 more
wiley   +1 more source

Human tissue-type plasminogen activator

open access: yesThrombosis and Haemostasis, 2014
E. Kruithof, S. Dunoyer-Geindre
semanticscholar   +1 more source

Current Practice Regarding Bleeding Disorders of Unknown Cause in the Netherlands: A National Survey

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction About 40%–70% of persons with a clinically relevant bleeding tendency who are referred to haemostasis experts are classified as having a ‘bleeding disorder of unknown cause’ (BDUC) as no biological entity can be found after extensive laboratory testing.
Caroline M. A. Mussert   +15 more
wiley   +1 more source

Lysosomal cysteine proteinases as mediators of inflammation and tumor spread [PDF]

open access: yes, 1992
Assfalg-Machleidt, Irmgard   +4 more
core   +1 more source

Unmasking Convergent Inflammatory and Oxidative Pathways in Asthma

open access: yes
Allergy, EarlyView.
Konstantinos Tourlakopoulos   +8 more
wiley   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur   +6 more
wiley   +1 more source

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