Results 251 to 260 of about 129,510 (314)

Efficacy and safety of glucagon‐like peptide 1 receptor agonists across all health outcomes in type 2 diabetes: An umbrella review and evidence map of randomised controlled trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1136-1149, February 2026.
Abstract Aim Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) have been established as effective treatments for type 2 diabetes, offering benefits beyond glycaemic control; however, their associations across multiple health outcomes remain insufficiently assessed.
Dongjin Yeo, Yeona Jo, Jinyoung Jeong, Yi Deun Jeong, Ho Geol Woo, Yejun Son, Sunyoung Kim, Sang Youl Rhee, Dong Keon Yon   +8 more
wiley   +1 more source

Tranexamic Acid for Hyperpigmentation Disorders: A Literature Review on Efficacy and Safety in Melasma and PIH

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hyperpigmentation disorders, including melasma and post‐inflammatory hyperpigmentation (PIH), are common dermatologic conditions associated with significant cosmetic and psychological burden. Tranexamic acid (TXA), an antifibrinolytic agent, has gained increasing attention due to its anti‐inflammatory and antimelanogenic properties.
Ahmed AlJabr, Aseel Muhana I. AlAnazi, Rakan Abdulkarim A. AlEtebi   +2 more
wiley   +1 more source

Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR), Growth Differentiation Factor-15 (GDF-15), and Soluble C5b-9 (sC5b-9) Levels Are Significantly Associated with Endothelial Injury Indices in CAR-T Cell Recipients [PDF]

Eleni Gavriilaki, Christos Demosthenous, Paschalis Evangelidis, Zoi Bousiou, Ioannis Batsis, Anna Vardi, Despina Mallouri, Eudoxia‐Evaggelia Koravou, Nikolaos Spyridis, Alkistis Panteliadou, Georgios Karavalakis, Marianna Masmanidou, Tasoula Touloumenidou, Apostolia Papalexandri, Christos Poziopoulos, Evangelia Yannaki, Ioanna Sakellari, Marianna Politou, Ioannis Papassotiriou   +18 more
openalex   +1 more source

Expression of recombinant human tissue-type plasminogen activator(t-PA) in mammalian cell system.

, 1988
Hiromi Ogino, K. Noda, Yosifumi HORISAWA, M Imai, Kazuharu KATO, Toshinori Kanamori, Masahiro Nobuhara   +6 more
openalex   +2 more sources

Environmental modulators of vascular physiology and inflammation

Experimental Physiology, Volume 111, Issue 2, Page 321-334, 1 February 2026.
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne, Anne Majumdar, Kalpana Surendranath, Mark R. Miller   +3 more
wiley   +1 more source

The Fibrinolytic System in Bacterial Sepsis: A Comprehensive Review of Current Assessment Methods. [PDF]

J Clin Med
Scarlatescu F, Scarlatescu E, Thachil J, Tomescu DR, Bartos D.   +4 more
europepmc   +1 more source

A Novel Modified Tissue-Type Plasminogen Activator (t-PA), E6010, Gradually Increases Coronary Blood Flow after Thrombolysis Compared with Native t-PA, Urokinase and Balloon Catheter Occlusion-Reperfusion

, 1994
Mamoru Saitō, Suguru Suzuki, Yoshiki Yui, Chuichi Kawai   +3 more
openalex   +1 more source

Isoquercetin and Zafirlukast Cooperatively Suppress Tumor Growth and Thromboinflammatory Signaling in a Xenograft Model of Ovarian Cancer

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay, Jason W. Hoskins, Jean‐Pierre Kinet, Thomas C. Lines, Daniel R. Kennedy   +4 more
wiley   +1 more source

Effects of aging on immune function and inflammatory biomarkers. [PDF]

Am J Transl Res
Dai C, Chen Q, Zhang Q, Chong Y, Wu Z, Wu Q, Gong J, Xia W, Liu W.   +8 more
europepmc   +1 more source