Results 291 to 300 of about 681,261 (380)

Proteomics of Urinary Extracellular Vesicles Highlight the Involvement of Vitronectin and the Fibrinolytic and TNF Pathways as Mechanisms Underlying Renal Fibrosis in Kidney Transplant Patients

open access: yesJournal of Extracellular Biology, Volume 4, Issue 6, June 2025.
ABSTRACT Vitronectin (VTN) is a potential non‐invasive biomarker for renal fibrosis, originally described in urinary extracellular vesicles (uEV) from kidney transplant patients (KTx). However, VTN's specific role in renal fibrosis is unclear, as it is involved in various physiological processes.
Marta Clos‐Sansalvador   +9 more
wiley   +1 more source

Angioedema following venipuncture in a patient on angiotensin‐converting enzyme inhibitor and dipeptidyl peptidase‐IV inhibitor therapy: A case report

open access: yesJEADV Clinical Practice, Volume 4, Issue 2, Page 510-513, June 2025.
Capsule SummaryAcquired angioedema (AAE) is a rare and potentially life‐threatening condition resulting from disruption of bradykinin (BK) metabolism, most often drug‐induced, with attacks typically triggered by major trauma. We report an uncommon case of AAE triggered locally by minor trauma—a forearm venipuncture—in a 77‐year‐old male taking ramipril
Adrien Bénic   +4 more
wiley   +1 more source

Preascitic Sodium Retention in Cirrhosis: A Role for Disregulated Proteolysis by Proprotein Convertases?

open access: yesLiver International Communications, Volume 6, Issue 2, June 2025.
ABSTRACT Loss of effective arterial blood volume, secondary hyperaldosteronism, adrenergic activation and nonosmotic hypersecretion of vasopressin induce sodium and water retention in cirrhotic patients with ascites. The mechanisms of sodium retention that precede ascites formation remain elusive.
Giovanni Sansoè   +2 more
wiley   +1 more source

Platelets: Novel Biomaterials for Cancer Diagnosis and Therapeutic Delivery

open access: yesMedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
Platelets, particularly tumor‐educated platelets (TEPs), play a crucial role in cancer diagnosis and treatment. TEPs undergo molecular changes in RNA and protein profiles, making them valuable biomarkers for diagnosis, prognosis, and monitoring. In nanomedicine, platelets serve as drug carriers in tumor‐targeted nanomaterials, enhancing specificity and
Xin Wang, Jie Chen, Hubing Shi
wiley   +1 more source

Association between PAI-1 gene - 657 4G/5G polymorphism and preeclampsia in Egyptian women: a case-control study. [PDF]

open access: yesBMC Pregnancy Childbirth
El-Khawaga OY   +6 more
europepmc   +1 more source

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