Results 61 to 70 of about 12,032,280 (304)
Treatment and seroconversion in a cohort of children suffering from recent chronic Chagas infection in Yoro, Honduras [PDF]
, 2009 Between 1999-2002, Médécins Sans Frontières-Spain implemented a project seeking to determine the efficacy and safety of benznidazole in the treatment of recent chronic Chagas disease in a cohort of seropositive children in the Yoro Department, Honduras ...
Bassets, Glòria +9 more
core +4 more sources
PLoS Neglected Tropical Diseases, 2021 The causative agent of Chagas disease, Trypanosoma cruzi, is transmitted by triatomine vectors. The insect is endemic in the Americas, including the United States, where epidemiological studies are limited, particularly in the Southwestern region.
F. Rodriguez +12 more
semanticscholar +1 more source
Structural organization of Trypanosoma cruzi [PDF]
Memórias do Instituto Oswaldo Cruz, 2009 Since the initial description of Trypanosoma cruzi by Carlos Chagas in 1909, several research groups have used different microscopic techniques to obtain detailed information about the various developmental stages found in the life cycle of this intracellular parasite.
openaire +4 more sources
Evaluation of a Novel Tc-24 Recombinant Antigen ELISA for Serologic Detection of Trypanosoma cruzi Infection in Dogs: A Pilot Study. [PDF]
Vet Med SciDogs are major reservoirs of Trypanosoma cruzi in Texas, United States. This study evaluated a novel Tc‐24 recombinant antigen ELISA for the serologic detection of Chagas disease in dogs and found it to have high sensitivity and specificity compared to existing commercial tests. The Tc‐24 Chagas ELISA provides a reliable tool for enhanced canine Chagas
Mejia R +7 more
europepmc +2 more sources
CpG and Interleukin-15 Synergize to Enhance IFN-γ Production by Activated CD8+ T Cells [PDF]
, 2012 Interleukin-15 (IL-15) regulates the development and maintenance of memory CD8+ T cells. Paradoxically, we previously reported that IL-15 could enhance CD8+ T-cell responses to IL-12, a proinflammatory cytokine required for optimal priming of effector ...
Cobb, Dustin +2 more
core +5 more sources
T. cruzi: sensitization to macrophage killing by eosinophil peroxidase.
Journal of Immunology, 1982 In this study, we report that trypomastigotes of T. cruzi coated with eosinophil peroxidase (EPO) become sensitized to killing by normal macrophages that are unable to kill uncoated organisms.
N. Nogueira, S. Klebanoff, Z. Cohn
semanticscholar +1 more source
, 2018 Dendropsophus cruzi (Pombal & Bastos, 1998) is a small hylid (male snout-to-vent length = 16.3–19.4 mm; female SVL = 21.3–25.0 mm) that is allocated in the D. microcephalus group (Faivovich et al. 2005). It is commonly found in Open and forested areas from Central Brazil to Provincia Velasco, Departamento de Santa Cruz, Bolivia (Frost 2017; Tessarolo ...
Andreani, Tainã Lucas +4 more
openaire +2 more sources
Endothelial Transmigration by Trypanosoma cruzi
PLoS ONE, 2013 Chagas heart disease, the leading cause of heart failure in Latin America, results from infection with the parasite Trypanosoma cruzi. Although T. cruzi disseminates intravascularly, how the parasite contends with the endothelial barrier to escape the bloodstream and infect tissues has not been described. Understanding the interaction between T.
Cheryl L. Olson +7 more
openaire +5 more sources
Parasites & Vectors, 2015 Background Chagas disease (caused by Trypanosoma cruzi) is the most important neglected tropical disease (NTD) in Latin America, infecting an estimated 5.7 million people in the 21 countries where it is endemic. It is one of the NTDs targeted for control
Jennifer K. Peterson +3 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2005 We assessed the distribution of Trypanosoma cruzi infection in peridomestic triatomines collected manually at a district-wide scale in rural villages around Olta, Western Argentina, and typed the isolated strains according to their pathogenicity to ...
Marta A Lauricella +4 more
doaj +1 more source