The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in nature for millions of years. The human infection, named Chagas disease, is a major public health problem for Latin America. T. cruzi is genetically highly diverse and
Andrade, S. G. +38 more
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Flow cytometric analysis and microsatellite genotyping reveal extensive DNA content variation in Trypanosoma cruzi populations and expose contrasts between natural and experimental hybrids. [PDF]
Trypanosoma cruzi exhibits remarkable genetic heterogeneity. This is evident at the nucleotide level but also structurally, in the form of karyotypic variation and DNA content differences between strains. Although natural populations of T.
Miles, M.A. +16 more
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Entomological surveillance of Trypanosoma cruzi vectors in Rio Grande do Norte, Brazil
Discontinuous entomological surveillance and persistent infestation by triatomines highlight the risk of Trypanosoma cruzi transmission. The diversity of triatomine species in the peridomicile shows the potential for colonization into the home. The wide distribution of Triatoma brasiliensis and Triatoma pseudomaculata accompanies high rates of ...
Letícia Mikardya Lima Sales +10 more
wiley +1 more source
Morpho-biological diversity of Trypanosoma cruzi has been known since Chagas' first works in 1909. Several further studies confirmed the morphological differences among the parasite strains, which were isolated from different reservoirs and vectors, as ...
Devera Rodolfo +2 more
doaj +3 more sources
Análise proteômica de formas tripomastigotas diferenciadas in vitro do Trypanosoma rangeli e caracterização de antígenos diferenciais ao Trypanosoma cruzi [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2012A distribuição simpátrica e o compartilhamento de hospedeiros e antígenos entre o Trypanosoma rangeli
Wagner, Glauber
core
The parasite Trypanasoma cruzi is responsible for Chagas disease and its triatomine vector, Rhodnius prolixus, has a symbiotic relationship with the soil bacterium, Rhodococcus rhodnii. R.
Fiecka, A. +3 more
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Deep sequencing of the Trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients. [PDF]
BACKGROUND: Chagas disease results from infection with the diploid protozoan parasite Trypanosoma cruzi. T. cruzi is highly genetically diverse, and multiclonal infections in individual hosts are common, but little studied.
Torrico, Faustino +52 more
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ABSTRACT Chagas disease remains a significant public health challenge in various endemic regions of Latin America. The persistence of vector‐borne transmission highlights the complexity of the issue and the limitations of traditional strategies. In this context, entomological surveillance plays a strategic and multifaceted role, not only in the early ...
Daniel Rodrigo de Lima Gomes +9 more
wiley +1 more source
The Trypanosoma cruzi metacyclic-specific protein Met-III associates with the nucleolus and contains independent amino and carboxyl terminal targeting elements. [PDF]
Metacyclogenesis in Trypanosoma cruzi involves the differentiation of replicating non-infective epimastigotes into non-replicating metacyclic trypomastigotes.
Gluenz, E +7 more
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ABSTRACT Visceral leishmaniasis (VL) is a human neglected tropical disease in which dogs participate as reservoirs of the etiological agent Leishmania chagasi. The identification of infected dogs is important to the control of VL, and recombinant proteins are strong antigen candidates for canine visceral leishmaniasis (CVL) serodiagnosis. In this work,
Thaís Viana Fialho Martins +12 more
wiley +1 more source

