Results 31 to 40 of about 10,211,329 (187)

Extraordinary Trypanosoma cruzi diversity within single mammalian reservoir hosts implies a mechanism of diversifying selection. [PDF]

, 2011
Trypanosoma cruzi is an evolutionarily ancient parasitic protozoan endemic to the Americas. Multiple genetic and phenotypic markers indicate that this parasite is highly diverse, with several divergent and discrete major genotypes reported.
Rivett-Carnac, John B, John B. Rivett-Carnac, Michael A. Miles, Lewis, Michael D., Martin S. Llewellyn, Fitzpatrick, Sinead, Matthew Yeo, Michael D. Lewis, Llewellyn, Martin S, Yeo, Matthew, Rivett-Carnac, John B., Miles, Michael A, Lewis, Michael D, Michael W. Gaunt, Gaunt, Michael W., Miles, Michael A., Gaunt, Michael W, Sinead Fitzpatrick, Llewellyn, Martin S.   +18 more
core   +1 more source

Genotyping of Trypanosoma cruzi: systematic selection of assays allowing rapid and accurate discrimination of all known lineages. [PDF]

, 2009
Trypanosoma cruzi, the agent of Chagas disease, can be subdivided into six discrete typing units (DTUs), TcI, TcIIa, TcIIb, TcIIc, TcIId or TcIIe, each having distinct epidemiologically important features.
Ma, Jonathan, Llewellyn, Martin S, Yeo, Matthew, Miles, Michael A, Lewis, M.D., Miles, M.A., Lewis, Michael D, Carrasco, Hernán J, Ma, J., Yeo, M., Carrasco, H.J., Llewellyn, M.S.   +11 more
core   +1 more source

Eco-epidemiological study of an endemic Chagas disease region in northern Colombia reveals the importance of Triatoma maculata (Hemiptera: Reduviidae), dogs and Didelphis marsupialis in Trypanosoma cruzi maintenance

Parasites & Vectors, 2015
Background In Colombia, Rhodnius prolixus and Triatoma dimidiata are the main domestic triatomine species known to transmit T. cruzi. However, there are multiple reports of T. cruzi transmission involving secondary vectors.
Omar Cantillo-Barraza, Edilson Garcés, Andrés Gómez-Palacio, Luis A. Cortés, André Pereira, Paula L. Marcet, Ana M. Jansen, Omar Triana-Chávez   +7 more
doaj   +1 more source

Effectiveness of Systemic Insecticide Dog Treatment for the Control of Chagas Disease in the Tropics

Biology, 2023
Chagas disease, caused by Trypanosoma cruzi and transmitted by triatomines, can lead to severe cardiac issues and mortality in many mammals. Recent studies have shown that systemic insecticide treatment of dogs is highly effective in killing triatomines.
Edem Fiatsonu, Aniruddha Deka, Martial L. Ndeffo-Mbah   +2 more
doaj   +1 more source

The genetic diversity of trypanosoma cruzi, multiclonality of natural populations and the characterisation of Paraguayan isolates and experimentally derived T. cruzi I. hydrids [PDF]

The aims of this PhD programme were: optimisation of conditions for clonal isolation of Trypanosoma cruzi from individual triatomine bugs and molecular characterisation of clonal isolates from field sites in Paraguay, with special consideration given
Yeo, Matthew
core   +1 more source

Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. [PDF]

, 2009
Trypanosoma cruzi, the etiological agent of Chagas disease, is highly genetically diverse. Numerous lines of evidence point to the existence of six stable genetic lineages or DTUs: TcI, TcIIa, TcIIb, TcIIc, TcIId, and TcIIe.
Torrico, Faustino, Acosta, Nidia, Torrico, F., Llewellyn Martin S., Nidia Acosta, Acosta Nidia, Jorge Vargas, Carrasco, H.J., Gaunt Michael W., Carrasco, Hernan J, Yeo, Matthew, Michael A Miles, Miles Michael A., Hernan J Carrasco, Gaunt, Michael W, Segovia Maikell, Vargas, Jorge, Torrico Faustino, Yeo Matthew, Miles, M.A., Michael D Lewis, Segovia, M., Yeo, M., Acosta, N., Matthew Yeo, Vargas Jorge, Llewellyn, Martin S, Martin S Llewellyn, Segovia, Maikell, Miles, Michael A, Lewis, M.D., Gaunt, M.W., Faustino Torrico, Lewis, Michael D, Carrasco Hernan J., Vargas, J., Maikell Segovia, Michael W Gaunt, Llewellyn, M.S., Lewis Michael D.   +39 more
core   +2 more sources

Broad patterns in domestic vector-borne Trypanosoma cruzi transmission dynamics: synanthropic animals and vector control

Parasites & Vectors, 2015
Background Chagas disease (caused by Trypanosoma cruzi) is the most important neglected tropical disease (NTD) in Latin America, infecting an estimated 5.7 million people in the 21 countries where it is endemic. It is one of the NTDs targeted for control
Jennifer K. Peterson, Sarah M. Bartsch, Bruce Y. Lee, Andrew P. Dobson   +3 more
doaj   +1 more source

Distribution and pathogenicity of Trypanosoma cruzi isolated from peridomestic populations of Triatoma infestans and Triatoma guasayana from rural Western Argentina

Memorias do Instituto Oswaldo Cruz, 2005
We assessed the distribution of Trypanosoma cruzi infection in peridomestic triatomines collected manually at a district-wide scale in rural villages around Olta, Western Argentina, and typed the isolated strains according to their pathogenicity to ...
Marta A Lauricella, Raúl L Stariolo, Adelina R Riarte, Elsa L Segura, Ricardo E Gürtler   +4 more
doaj   +1 more source

Synthesis of Naphthoquinones by Pd‐Catalyzed Heck–Matsuda Arylation of Lapachol

European Journal of Organic Chemistry, EarlyView.
Direct Heck–Matsuda arylation of lapachol enables the efficient synthesis of diverse naphthoquinones under homogeneous and heterogeneous palladium catalysis. The methodology features broad substrate scope, gram‐scale applicability, and provides a practical platform for quinone diversification.
Breno U. de Abreu, Renata G. Almeida, Ana L. C. Silveira, Leonardo A. Matos, Willian X. C. Oliveira, Maria H. Araujo, Victor F. S. Ramos, Rubem F. S. Menna‐Barreto, Chandrakant B. Nichinde, Felipe Fantuzzi, Edmond Gravel, Eric Doris, Eufrânio N. da Silva Júnior, Guilherme A. M. Jardim   +13 more
wiley   +1 more source

The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence. [PDF]

, 2015
BACKGROUND: The neglected parasitic infection Chagas disease is rapidly becoming a globalised public health issue due to migration. There are only two anti-parasitic drugs available to treat this disease, benznidazole and nifurtimox. Thus it is important
Fortes Francisco, A, Martin C Taylor, John M Kelly, Michael D Lewis, Shane R. Wilkinson (721807), Fortes Francisco, Amanda, Amanda Fortes Francisco (330407), Taylor, Martin C, Lewis, MD, Amanda Fortes Francisco, Wilkinson, SR, Michael D. Lewis (172100), Taylor, MC, Lewis, Michael D, Kelly, JM, Shane R Wilkinson, Wilkinson, Shane R, Kelly, John M, Martin C. Taylor (449215), John M. Kelly (488103)   +19 more
core   +2 more sources