Results 21 to 30 of about 3,869 (134)
The resting electrocardiogram of t. cruzi-infected rats [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 1987 A total of 125 rats were infected with the Colômbia strain of T. cruzi (2000 parasites/g) shortly after weaning. Of these, 58 survived the acute phase and were used in the present experiment. Twenty eight similar but not infected rats served as controls. All rats were submitted to the resting ECG When they were 6 months old.
Bestetti, Reinaldo B. +4 more
openaire +5 more sources
BMC Genomics, 2018 Background Trypanosoma conorhini and Trypanosoma rangeli, like Trypanosoma cruzi, are kinetoplastid protist parasites of mammals displaying divergent hosts, geographic ranges and lifestyles. Largely nonpathogenic T. rangeli and T.
Katie R Bradwell +12 more
doaj +1 more source
Biotherapic T. cruzi 17DH when continuously used clinically improves mice infected with T. cruzi.
International Journal of High Dilution Research - ISSN 1982-6206, 2021 Introduction: In Trypanosoma cruzi infection, the pathogenesis is the result of a rupture in the host - parasite relationship [1]. This rupture is related to the imbalance of the vital force of the host, expressed through signs and symptoms, defined by Hahnemann (1995)[2] as being the source of the disease.
Denise Lessa Aleixo +6 more
openaire +2 more sources
PLoS Neglected Tropical Diseases, 2013 BackgroundAdults with chronic Trypanosoma cruzi exhibit a poorly functional T cell compartment, characterized by monofunctional (IFN-γ-only secreting) parasite-specific T cells and increased levels of terminally differentiated T cells.
María C Albareda +11 more
doaj +1 more source
Frontiers in Immunology, 2018 Few studies investigate the major protein antigens targeted by the antibody diversity of infected mice with Trypanosoma cruzi. To detect global IgG antibody specificities, sera from infected mice were immunoblotted against whole T. cruzi extracts.
Fabricio Montalvão +15 more
doaj +1 more source
The FASEB Journal, 2008 The T‐box transcription factor expressed in T cells (T‐bet) is a critical regulator of T cell effector functions, particularly interferon gamma (IFN‐γ) production. We investigated the role of T‐bet in immunity to T.
Ronald B Smeltz +4 more
openaire +1 more source
CD8+ T cells in Trypanosoma cruzi infection [PDF]
Seminars in Immunopathology, 2015 Trypanosoma cruzi infection and Chagas disease remains among the most neglected of the neglected tropical diseases. Despite this, studies of the immune response to T. cruzi have provided new insights in immunology and guidance for approaches for prevention and treatment of the disease. T.
openaire +2 more sources
Revista do Instituto de Medicina Tropical de São Paulo, 2007 Trypanosoma rangeli is non pathogenic for humans but of important medical and epidemiological interest because it shares vertebrate hosts, insect vectors, reservoirs and geographic areas with T. cruzi, the etiological agent of Chagas disease.
Paula Ximena Pavia +4 more
doaj +1 more source
Parasites & Vectors, 2022 Background Components of the antioxidant defense system in Trypanosoma cruzi are potential targets for new drug development. Superoxide dismutases (SODs) constitute key components of antioxidant defense systems, removing excess superoxide anions by ...
Jéssica Hickson +10 more
doaj +1 more source
Xanthine Analogs Suppress Trypanosoma cruzi Infection In Vitro Using PDEs as Targets
Microbiology Research, 2022 Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, has infected 6 million people, putting 70 million people at risk worldwide. Presently, very limited drugs are available, and these have severe side effects.
Amita R. Banga +9 more
doaj +1 more source