Results 11 to 20 of about 10,211,329 (187)
Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses. [PDF]
PLoS Neglected Tropical Diseases, 2016 BACKGROUND:Chagas disease is the highest impact parasitic disease in Latin America. We have proposed that changes in Trypanosoma cruzi-specific immune responses might serve as surrogate indicators of treatment success. Herein, we addressed in a long-term María G Alvarez, Graciela L Bertocchi, Gretchen Cooley, María C Albareda, Rodolfo Viotti, Damián E Perez-Mazliah, Bruno Lococo, Melisa Castro Eiro, Susana A Laucella, Rick L Tarleton +9 moredoaj +1 more sourceTrypanosoma cruzi: ancestral genomes and population structure
Memorias do Instituto Oswaldo Cruz, 2009 Although the genome of Trypanosoma cruzi has been completely sequenced, little is known about its population structure and evolution. Since 1999, two major evolutionary lineages presenting distinct epidemiological characteristics have been recognised: T. Sérgio DJ Pena, Carlos Renato Machado, Andréa Mara Macedo +2 moredoaj +1 more sourceComparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei. [PDF]
, 2012 BACKGROUND: Trypanosoma cruzi marinkellei is a bat-associated parasite of the subgenus Schizotrypanum and it is regarded as a T. cruzi subspecies. Here we report a draft genome sequence of T. c. marinkellei and comparison with T. c. cruzi.Andersson, B., Cornelis J Marinkelle, Kevin M Tyler, Butler, Claire E, Messenger, L.A., Talavera-López, Carlos, Björn Andersson, Louisa A Messenger, Claire E Butler, Michael A Miles, Ochaya, S., Marinkelle, Cornelis J, Butler, Claire, Talavera-López, C., Carlos Talavera-López, Miles, M.A., Michael D Lewis, Ochaya, Stephen, Messenger, Louisa A, Butler, C.E., Stephen Ochaya, Franzén, Oscar, Oscar Franzén, Llewellyn, Martin S, Martin S Llewellyn, Tyler, K.M., Miles, Michael A, Lewis, M.D., Lewis, Michael D, Andersson, Björn, Franzén, O., Tyler, Kevin, Tyler, Kevin M, Llewellyn, M.S., Marinkelle, C.J., Tyler Kevin M, Messenger, LA, Franzen, O, Miles Michael A, Tyler, KM, Andersson Björn, Talavera-López Carlos, Ochaya Stephen, Miles, MA, Marinkelle Cornelis J, Lewis Michael D, Llewellyn Martin S, Franzén Oscar, Butler Claire E, Ochaya, S,, Messenger Louisa A, Talavera-Lopez, C, Lewis, MD, Llewellyn, MS, Marinkelle, CJ, Butler, CE +55 morecore +1 more sourcePolyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults.
PLoS Neglected Tropical Diseases, 2013 BackgroundAdults with chronic Trypanosoma cruzi exhibit a poorly functional T cell compartment, characterized by monofunctional (IFN-γ-only secreting) parasite-specific T cells and increased levels of terminally differentiated T cells.María C Albareda, Ana M De Rissio, Gonzalo Tomas, Alicia Serjan, María G Alvarez, Rodolfo Viotti, Laura E Fichera, Mónica I Esteva, Daniel Potente, Alejandro Armenti, Rick L Tarleton, Susana A Laucella +11 moredoaj +1 more sourceGenomic comparison of Trypanosoma conorhini and Trypanosoma rangeli to Trypanosoma cruzi strains of high and low virulence
BMC Genomics, 2018 Background Trypanosoma conorhini and Trypanosoma rangeli, like Trypanosoma cruzi, are kinetoplastid protist parasites of mammals displaying divergent hosts, geographic ranges and lifestyles. Largely nonpathogenic T. rangeli and T.Katie R Bradwell, Vishal N Koparde, Andrey V Matveyev, Myrna G Serrano, João M P Alves, Hardik Parikh, Bernice Huang, Vladimir Lee, Oneida Espinosa-Alvarez, Paola A Ortiz, André G Costa-Martins, Marta M G Teixeira, Gregory A Buck +12 moredoaj +1 more sourceAntibody Repertoires Identify β-Tubulin as a Host Protective Parasite Antigen in Mice Infected With Trypanosoma cruzi
Frontiers in Immunology, 2018 Few studies investigate the major protein antigens targeted by the antibody diversity of infected mice with Trypanosoma cruzi. To detect global IgG antibody specificities, sera from infected mice were immunoblotted against whole T. cruzi extracts.Fabricio Montalvão, Fabricio Montalvão, Danielle Oliveira Nascimento, Marise P. Nunes, Carolina M. Koeller, Alexandre Morrot, Alexandre Morrot, Leticia Miranda S. Lery, Paulo M. Bisch, Santuza M. R. Teixeira, Rita Vasconcellos, Leonardo Freire-de-Lima, Marcela F. Lopes, Norton Heise, George A. DosReis, Célio Geraldo Freire-de-Lima +15 moredoaj +1 more sourceBradykinin B2 receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses [PDF]
, 2007 Although the concept that dendritic cells (DCs) recognize pathogens through the engagement of Toll-like receptors is widely accepted, we recently suggested that immature DCs might sense kinin-releasing strains of Trypanosoma cruzi through the triggering ...Müller-Esterl Werner, Alessandra Granato, Schmitz Verônica, Scharfstein Julio, Tanowitz Herbert B, Scharfstein, Julio, Werner Müller-Esterl, Fnu Nagajyothi, de Arruda Luciana Barros, Nagajyothi, Fnu, Granato Alessandra, Pesquero João B, Müller-Esterl, Werner, Schmitz, Verônica, Luciana Barros de Arruda, Alexandre Morrot, Granato, Alessandra, Barros de Arruda, Luciana, Morrot Alexandre, Monteiro, Ana Carolina, Tanowitz, Herbert B., Julio Scharfstein, Nagajyothi Fnu, Morrot, Alexandre, Verônica Schmitz, João B Pesquero, Pesquero, João B., Monteiro Ana Carolina, Ana Carolina Monteiro, Herbert B Tanowitz +29 morecore +2 more sourcesRecent, independent and anthropogenic origins of Trypanosoma cruzi hybrids. [PDF]
, 2011 The single celled eukaryote Trypanosoma cruzi, a parasite transmitted by numerous species of triatomine bug in the Americas, causes Chagas disease in humans. T.Michael A. Miles, Acosta, Nidia, Llewellyn Martin S., Nidia Acosta, Acosta Nidia, Gaunt Michael W., Carlton, J.M., Yeo, Matthew, Michael A Miles, Miles Michael A., Michael W. Gaunt, Gaunt, Michael W, Yeo Matthew, Miles, M.A., Michael D Lewis, Yeo, M., Acosta, N., Martin S. Llewellyn, Matthew Yeo, Michael D. Lewis, Llewellyn, Martin S, Martin S Llewellyn, Miles, Michael A, Lewis, M.D., Gaunt, M.W., Lewis, Michael D, Michael W Gaunt, Llewellyn, M.S., Lewis Michael D. +28 morecore +2 more sourcesMultilocus sequence typing (MLST) for lineage assignment and high resolution diversity studies in Trypanosoma cruzi. [PDF]
, 2011 BACKGROUND: Multilocus sequence typing (MLST) is a powerful and highly discriminatory method for analysing pathogen population structure and epidemiology. Trypanosoma cruzi, the protozoan agent of American trypanosomiasis (Chagas disease), has remarkable Michael A. Miles, Acosta , N,, Llewellyn Martin S., Nidia Acosta, Louisa A Messenger, Acosta Nidia, Bhattacharyya Tapan, Carrasco, Hernan J, Yeo, Matthew, Hernan J Carrasco, Bhattacharyya , T,, Miles, Michael A., Llewellyn , MS,, Isabel L. Mauricio, Yeo Matthew, Miles, M.A., Michael D Lewis, Messenger, Louisa A, Yeo, M., Acosta, N., Mauricio, Isabel Larguinho, Matthew Yeo, Patricio Diosque, Llewellyn, Martin S, Martin S Llewellyn, Miles, Michael A, Lewis, M.D., Messenger Louisa A., Diosque, P., Lewis, Michael D, Miles , MA., Carrasco Hernan J., Llewellyn, Martin S., Llewellyn, M.S., Lewis Michael D., Messenger, L.A., Acosta, Nidia, Lewis, Michael D., Carrasco, H.J., Mauricio, I.L., Mauricio, Isabel L., Messenger, Loisa A., Lewis , MD,, Yeo , M,, Michael A Miles, Miles Michael A., Bhattacharyya, Tapan, Louisa A. Messenger, Carrasco , HJ,, Messenger , LA,, Isabel L Mauricio, Bhattacharyya, T., Diosque Patricio, Hernan J. Carrasco, Martin S. Llewellyn, Diosque, Patricio, Michael D. Lewis, Mauricio, Isabel L, Mauricio Isabel L., Diosque , P,, Tapan Bhattacharyya, Carrasco, Hernán J. +61 morecore +2 more sourcesMultiple mitochondrial introgression events and heteroplasmy in trypanosoma cruzi revealed by maxicircle MLST and next generation sequencing. [PDF]
, 2012 BACKGROUND: Mitochondrial DNA is a valuable taxonomic marker due to its relatively fast rate of evolution. In Trypanosoma cruzi, the causative agent of Chagas disease, the mitochondrial genome has a unique structural organization consisting of 20-50 ...Andersson, B., Andersson, B,, Carrasco, H., Miles, M., Llewellyn Martin S., Louisa A Messenger, Messenger, LA, Bhattacharyya Tapan, Franzen, O, Carrasco, Hernan J, Andersson Björn, Messenger, L., Hernan J Carrasco, Hernan J. Carrasco (5649058), Martin S. Llewellyn (155605), Miles, M.A., Michael D Lewis, Messenger, Louisa A, Louisa A. Messenger (172069), Llewellyn, M., Oscar Franzén, Michael A. Miles (43726), Llewellyn, Martin S, Ramírez, J.D., Martin S Llewellyn, Bhattacharyya, T, Miles, MA, Miles, Michael A, Lewis, M.D., Messenger Louisa A., Tapan Bhattacharyya (172083), Lewis, Michael D, Carrasco Hernan J., Llewellyn, M.S., Lewis Michael D., Ramírez Juan David, Messenger, L.A., Björn Andersson, Juan David Ramírez, Carrasco, H.J., Andresson, B., Michael D. Lewis (172100), Michael A Miles, Miles Michael A., Bhattacharyya, Tapan, Ramirez, J.-D., Franzén Oscar, David, Ramirez J, Juan David Ramírez (172106), Ramírez, Juan David, Lewis, M., Björn Andersson (2663065), Carrasco, HJ, Bhattacharyya, T., Traub-Csekö, Y.M., Franzén, Oscar, Oscar Franzén (172092), Llewellyn, MS, Lewis, MD, Andersson, Björn, Franzén, O., Tapan Bhattacharyya +61 morecore +2 more sources
