Results 11 to 20 of about 67,305 (212)

CD8+ T cells in Trypanosoma cruzi infection [PDF]

Current Opinion in Immunology, 2009
CD8(+) T cells have emerged as crucial players in the control of a number of protozoan pathogens, including Trypanosoma cruzi, the agent of human Chagas disease. The recent identification of the dominant targets of T. cruzi-specific T cells has allowed investigators to follow the generation of and document the functionality of T cell responses in both ...
Angel M, Padilla, Juan M, Bustamante, Rick L, Tarleton   +2 more
openaire   +2 more sources

Biotherapic T. cruzi 17DH when continuously used clinically improves mice infected with T. cruzi.

International Journal of High Dilution Research - ISSN 1982-6206, 2021
Introduction: In Trypanosoma cruzi infection, the pathogenesis is the result of a rupture in the host - parasite relationship [1]. This rupture is related to the imbalance of the vital force of the host, expressed through signs and symptoms, defined by Hahnemann (1995)[2] as being the source of the disease.
Denise Lessa Aleixo, Érika Cristina Ferreira Cristina Ferreira Ferreira, Caroline Felicio Braga, Carina Ribeiro Lopes, Gislaine Janaina Sanchez Falkowski, Patricia Flora Sandri, Silvana Marques de Araujo   +6 more
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Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Chagas disease is the highest impact parasitic disease in Latin America. We have proposed that changes in Trypanosoma cruzi-specific immune responses might serve as surrogate indicators of treatment success. Herein, we addressed in a long-term
María G Alvarez, Graciela L Bertocchi, Gretchen Cooley, María C Albareda, Rodolfo Viotti, Damián E Perez-Mazliah, Bruno Lococo, Melisa Castro Eiro, Susana A Laucella, Rick L Tarleton   +9 more
doaj   +1 more source

High Trypanosoma spp. diversity is maintained by bats and triatomines in Espírito Santo state, Brazil [PDF]

, 2017
The aim of this study was to reevaluate the ecology of an area in the Atlantic Forest, southeast Brazil, where Chagas disease (CD) has been found to occur.
Costa, Leonora Pires, Costa, Luciana M., Dario, Maria Augusta, Jansen, Ana Maria, Leite, Yuri Luiz Reis, Lisboa, Cristiane Varella, Llewellyn, Martin S., Moratelli, Ricardo, Nascimento, Monique Pereira, Roque, André Luiz Rodrigues, Xavier, Samanta Cristina das Chagas   +10 more
core   +9 more sources

Trypanosoma cruzi: ancestral genomes and population structure

Memorias do Instituto Oswaldo Cruz, 2009
Although the genome of Trypanosoma cruzi has been completely sequenced, little is known about its population structure and evolution. Since 1999, two major evolutionary lineages presenting distinct epidemiological characteristics have been recognised: T.
Sérgio DJ Pena, Carlos Renato Machado, Andréa Mara Macedo   +2 more
doaj   +1 more source

Genomic comparison of Trypanosoma conorhini and Trypanosoma rangeli to Trypanosoma cruzi strains of high and low virulence

BMC Genomics, 2018
Background Trypanosoma conorhini and Trypanosoma rangeli, like Trypanosoma cruzi, are kinetoplastid protist parasites of mammals displaying divergent hosts, geographic ranges and lifestyles. Largely nonpathogenic T. rangeli and T.
Katie R Bradwell, Vishal N Koparde, Andrey V Matveyev, Myrna G Serrano, João M P Alves, Hardik Parikh, Bernice Huang, Vladimir Lee, Oneida Espinosa-Alvarez, Paola A Ortiz, André G Costa-Martins, Marta M G Teixeira, Gregory A Buck   +12 more
doaj   +1 more source

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]

, 2016
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida, Andrade, Antunez, Aune, Avilan, Bern, Cardillo, Carlier, Carnaud, Cesari, Collins, Culbertson, Dowling, Duthie, Duthie, Duthie, Filtjens, Fraser, Frosch, Gritz, Hanke, Keating, Lieke, Lieke, Mekkawy, Meyer Zum Buschenfelde, Mondino, Nagata, Nogueira, Pettengill, Pinazo, Rassi, Robertson, Rottenberg, Santana, Sardinha, Stevenaert, Taveirne, Torrico, Truyens, Truyens, Truyens, Une, Van Beneden, Van Beneden, Van Den Broeck, Van Den Broeck, Vassalli, Wen   +48 more
core   +2 more sources

NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production. [PDF]

PLoS Neglected Tropical Diseases, 2013
Trypanosoma cruzi (T. cruzi) is an intracellular protozoan parasite and the etiological agent of Chagas disease, a chronic infectious illness that affects millions of people worldwide. Although the role of TLR and Nod1 in the control of T.
Virginia M Gonçalves, Kely C Matteucci, Carina L Buzzo, Bruna H Miollo, Danny Ferrante, Ana C Torrecilhas, Mauricio M Rodrigues, Jose M Alvarez, Karina R Bortoluci   +8 more
doaj   +1 more source

Habitat Management to Reduce Human Exposure to Trypanosoma cruzi and Western Conenose Bugs (Triatoma protracta). [PDF]

, 2016
Chagas disease, which manifests as cardiomyopathy and severe gastrointestinal dysfunction, is caused by Trypanosoma cruzi, a vector-borne parasite. In California, the vector Triatoma protracta frequently colonizes woodrat (Neotoma spp.) lodges, but may ...
Conrad, Patricia, Goldstein, Tracey, Mazet, Jonna, Niemela, Michael, Shender, Lisa   +4 more
core   +2 more sources

The resting electrocardiogram of t. cruzi-infected rats [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1987
A total of 125 rats were infected with the Colômbia strain of T. cruzi (2000 parasites/g) shortly after weaning. Of these, 58 survived the acute phase and were used in the present experiment. Twenty eight similar but not infected rats served as controls. All rats were submitted to the resting ECG When they were 6 months old.
Bestetti, Reinaldo B., Soares, Edson G., Sales-Neto, Vicente N., Araújo, Rosaly Corrêa de, Oliveira, J. Samuel M.   +4 more
openaire   +5 more sources