Results 61 to 70 of about 3,869 (134)

Protective role of TRPV1+ nociceptive neurons communication to macrophages against T. cruzi infection in mice

Brain, Behavior, & Immunity - Health
Chagas’ disease is a life-threatening condition caused by Trypanosoma cruzi. Patients with chronic disease may develop gastrointestinal, neurological, or associated neuro-digestive dysfunctions. CNS invasion by T.
Sergio M. Borghi, Aparecida D. Malvezi, Maria Isabel Lovo-Martins, Victor Fattori, Tiago H. Zaninelli, Mariana M. Bertozzi, Camila R. Ferraz, Thiago M. Cunha, Rubia Casagrande, Marli C. Martins-Pinge, Phileno Pinge-Filho, Waldiceu A. Verri, Jr.   +11 more
doaj   +1 more source

Repertoire, genealogy and genomic organization of cruzipain and homologous genes in Trypanosoma cruzi, T. cruzi-like and other trypanosome species. [PDF]

PLoS ONE, 2012
Trypanosoma cruzi, the agent of Chagas disease, is a complex of genetically diverse isolates highly phylogenetically related to T. cruzi-like species, Trypanosoma cruzi marinkellei and Trypanosoma dionisii, all sharing morphology of blood and culture ...
Luciana Lima, Paola A Ortiz, Flávia Maia da Silva, João Marcelo P Alves, Myrna G Serrano, Alane P Cortez, Silvia C Alfieri, Gregory A Buck, Marta M G Teixeira   +8 more
doaj   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf, Paul Nouri, Frédéric Galisson, Laetitia Daury, Marie‐France Giraud, Olivier Lambert, Cédric Orelle, Lionel Ballut, Elise Kaplan, Jean‐Michel Jault, Cécile Gonzalez   +10 more
wiley   +1 more source

Assessment of the Performance of Indirect Immunofluorescence Assay for Chagas Disease in Dogs Using a Reference Panel of Four Chimeric Proteins

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
We evaluated the performance of an indirect immunofluorescence (IIF) assay for detecting anti‐Trypanosoma cruzi IgG in dogs using four chimeric IBMP antigens and latent class analysis. The IIF assay showed suboptimal sensitivity and overall accuracy compared to ELISA and LCA‐based methods.
Ângelo Antônio Oliveira Silva, Thaliane França Costa, Natália Dantas Fontes, Emily Ferreira Santos, Ana Vitória Verde Oliveira Rocha, Leandro Macedo Miranda, Fernando Almeida‐Souza, Francisco Borges Costa, Rita de Maria Seabra Nogueira, Daniel Dias Sampaio, Paola Alejandra Fiorani Celedon, Nilson Ivo Tonin Zanchin, Andréa Pereira da Costa, Fred Luciano Neves Santos   +13 more
wiley   +1 more source

Trypanosoma Cruzi Infection in Dogs and Cats and Household Seroreactivity to T. Cruzi in a Rural Community in Northeast Brazil [PDF]

The American Journal of Tropical Medicine and Hygiene, 1978
The prevalence of Trypanosoma cruzi parasitemia as determined by xenodiagnosis on domestic dogs and cats was correlated with household rates of seroreactivity to T. cruzi and household Panstrongylus megistus infestation in a rural area in northeast Brazil where P. megistus was the only domiciliary triatomine vector. T.
K E, Mott, E A, Mota, I, Sherlock, R, Hoff, T M, Muniz, T S, Oliveira, C C, Draper   +6 more
openaire   +2 more sources

Antipredatory Strategies of Anurans: An Updated Conceptual Review

Ethology, Volume 132, Issue 9, Page 662-708, September 2026.
To unravel the evolutionary dynamics of predator–prey interactions, we propose an updated, three‐tiered classification of anuran antipredatory strategies. By mapping non‐behavioral, individual, and group defenses across five functional phases, this integrative framework introduces the concept of synergetic coupling.
Ubiratã Ferreira Souza, Lucas Rosado Mendonça, Carlos Jared, L. Felipe Toledo   +3 more
wiley   +1 more source

Astrocyte Apoptosis and HIV Replication Are Modulated in Host Cells Coinfected with Trypanosoma cruzi

Frontiers in Cellular and Infection Microbiology, 2017
The protozoan Trypanosoma cruzi is the etiological agent of Chagas disease. In immunosuppressed individuals, as it occurs in the coinfection with human immunodeficiency virus (HIV), the central nervous system may be affected. In this regard, reactivation
Javier M. Urquiza, Javier M. Urquiza, Juan M. Burgos, Juan M. Burgos, Diego S. Ojeda, Diego S. Ojeda, Carla A. Pascuale, Carla A. Pascuale, M. Susana Leguizamón, M. Susana Leguizamón, Jorge F. Quarleri, Jorge F. Quarleri   +11 more
doaj   +1 more source

Editorial: Unravelling T. cruzi Biology [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
Martin Craig Taylor, Noelia Lander, Nobuko Yoshida   +2 more
openaire   +3 more sources

Exploring Biological Properties of Manganese(II)‐Phenanthroline‐Based Complexes: In Vitro Insights

ChemistrySelect, Volume 11, Issue 29, 3 August 2026.
Four Mn(II) complexes with phenanthroline derivatives were studied. These compounds were tested against several parasites and different human cancer cells. Despite its cytotoxicity on breast cancer, DNA seems not to be the main biological target. These complexes can drive the design and development of new metal‐based agents with improved biological ...
Roberto S. Silva, Marcos V. Palmeira‐Mello, Mikaelly P. Caet, Celisnolia M. Leite, Arieli B. Portugal, Pedro H. Machado, Alexandre B. Carvalho, Isabel Correia, Leonardo M. Moreira, Thatiana L. B. V. Simão, Elena Lasunskaia, Michelle F. Muzitano, José L. Nepomuceno‐Silva, João L. M. Wanderley, Javier Ellena, Alzir A. Batista, Mario S. Schultz   +16 more
wiley   +1 more source

Exploring Trypanosoma cruzi transmission dynamics in an acute Chagas disease outbreak using next-generation sequencing

Parasites & Vectors
Background Chagas disease (CD), caused by Trypanosoma cruzi, poses a major global public health challenge. Although vector-borne transmission is the primary mode of infection, oral transmission is increasingly concerning. Methods This study utilized long-
Lissa Cruz-Saavedra, Carlos Ospina, Stivenn A. Gutiérrez, Jeiczon Jaimes-Dueñez, Omar Cantillo-Barraza, Carolina Hernández, Francisco Álvarez, María Blanco, Bernardo Leal, Lida Martínez, Manuel Medina, Mabel Medina, Silvia Valdivieso, Lauren Natalia Ramirez Celis, Luz H. Patiño, Juan David Ramírez   +15 more
doaj   +1 more source