Results 61 to 70 of about 42,346 (181)

Different infective forms trigger distinct immune response in experimental Chagas disease. [PDF]

, 2012
Although metacyclic and blood trypomastigotes are completely functional in relation to parasite-host interaction and/or target cell invasion, they differ in the molecules present on the surface.
Olindo Assis Martins-Filho, Carneiro Cláudia Martins, Martins-Filho, Olindo Assis, Alexandre Barbosa Reis, Cláudia Martins Carneiro, Francisco Amanda Fortes, Washington Luiz Tafuri, Carvalho, Andrea Teixeira, Machado Evandro Marques de Meneses, Nogueira, Nívia Carolina, Franscisco, Amanda Fortes, Evandro Marques de Meneses Machado, Vieira, Paula Melo de Abreu, Fonseca, Kátia da Silva, Francisco, Amanda Fortes, Andrea Teixeira-Carvalho, Paula Melo de Abreu Vieira, Nogueira, N??via Carolina, Machado, Evandro Marques de Menezes, Vieira Paula Melo de Abreu, Machado, Evandro Marques de Meneses, Tafuri, Washington Luiz, Reis Alexandre Barbosa, Teixeira-Carvalho Andrea, Reis, Alexandre Barbosa, Martins-Filho Olindo Assis, Nívia Carolina Nogueira, Kátia da Silva Fonseca, Carvalho, Andréa Teixeira de, Nogueira Nívia Carolina, Amanda Fortes Francisco, Tafuri Washington Luiz, Teixeira-Carvalho, Andrea, Carneiro, Cláudia Martins, Martins Filho, Olindo Assis, Fonseca Kátia da Silva   +35 more
core   +1 more source

Repertoire, genealogy and genomic organization of cruzipain and homologous genes in Trypanosoma cruzi, T. cruzi-like and other trypanosome species. [PDF]

PLoS ONE, 2012
Trypanosoma cruzi, the agent of Chagas disease, is a complex of genetically diverse isolates highly phylogenetically related to T. cruzi-like species, Trypanosoma cruzi marinkellei and Trypanosoma dionisii, all sharing morphology of blood and culture ...
Luciana Lima, Paola A Ortiz, Flávia Maia da Silva, João Marcelo P Alves, Myrna G Serrano, Alane P Cortez, Silvia C Alfieri, Gregory A Buck, Marta M G Teixeira   +8 more
doaj   +1 more source

North American import? Charting the origins of an enigmatic Trypanosoma cruzi domestic genotype. [PDF]

, 2012
BACKGROUND: Trypanosoma cruzi, the agent of Chagas disease, is currently recognized as a complex of six lineages or Discrete Typing Units (DTU): TcI-TcVI. Recent studies have identified a divergent group within TcI - TcI(DOM). TcI(DOM).
Perrin, P.B., Martínez-Ibarra Alejandro J, Zumaya-Estrada, Federico A, Lopez-Ordonez, T., Segovia Maikel, Hernan V Carrasco, Pamela M Pennington, Louisa A Messenger, Miles Michael A, Carrasco, Hernan V, Martínez-Ibarra, Alejandro J, Segovia, Maikel, Michael D Lewis, Messenger, Louisa A, Everhart, R.S., Miles, M.A., Llewellyn, Martin S, Martin S Llewellyn, Miles, Michael A, Federico A Zumaya-Estrada, Lewis, Michael D, Lewis Michael D, Cordon-Rosales, Celia, Lopez-Ordonez Teresa, Jimenez-Maldonado, M., Cordon-Rosales Celia, Teresa Lopez-Ordonez, Pennington Pamela M, Pennington, Pamela M, Cordon-Rosales, C., Llewellyn, M.S., Llewellyn Martin S, Trapp, S.K., Lewis, M.D., Martinez-Ibarra, A.J., Pennington, P.M., Lopez-Ordonez, Teresa, Arango-Lasprilla, J.C., Michael A Miles, Flores-Lopez, Carlos A, Flores-Lopez Carlos A, Messenger Louisa A, Messenger, L.A., Flores-Lopez, C.A., Carrasco Hernan V, Carlos A Flores-Lopez, Leibach, G.G., Carrasco, H.V., Celia Cordon-Rosales, Alejandro J Martínez-Ibarra, Zumaya-Estrada, F.A., Maikel Segovia, Segovia, M., Cabrera, T.V., Zumaya-Estrada Federico A   +54 more
core   +1 more source

Chagas disease in Canadian blood donors: 15 years of selective testing

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Chagas disease (Trypanosoma cruzi), prevalent in Mexico, Central and South America, can be transfusion‐transmitted. Selective serological testing of blood donors was implemented over 15 years ago. We describe the trends in infections and characteristics of donors selected for testing.
Sheila F. O'Brien, Mindy Goldman, Antoine Lewin, Samra Uzicanin, Wenli Fan, Steven J. Drews   +5 more
wiley   +1 more source

Regulation and use of the extracellular matrix by Trypanosoma cruzi during early infection

Frontiers in Immunology, 2012
Chagas disease, which was once thought to be confined to endemic regions of Latin America, has now gone global becoming a new worldwide challenge. For more than a century since its discovery, it has remained neglected with no effective drugs or vaccines.
Pius N. Nde, Maria F Lima, Candice A Johnson, Siddharth ePratap, Fernando eVillalta   +4 more
doaj   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

Protein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone, Serena Spadone, Anna Lucia Francavilla, Sara Morselli, Sabino Todisco, Margherita Ortalli, Jairo Alfonso Mendoza‐Roldan, Valeria Scaglione, Maria Noemi Sgobba, Lorenzo Guerra, Federica Belluti, Stefania Varani, Domenico Otranto, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri   +15 more
wiley   +1 more source

A Novel Polyphosphate‐Degrading Enzyme Confers Growth on Exogenous Polyphosphate in the Archaeon Haloferax volcanii

Environmental Microbiology, Volume 28, Issue 7, July 2026.
A novel polyP‐degrading enzyme with an activity differing from those currently known was found in Haloferax volcanii, conferring the ability for this microbe to grow on extracellular polyP. These findings further our understanding of the potential ecological roles of polyP and how archaea metabolise this essential biopolymer.
Jack W. F. Nicholls, Vincent O'Flaherty, Timothy M. Lenton, John W. McGrath, Jason P. Chin   +4 more
wiley   +1 more source

DNA content analysis allows discrimination between Trypanosoma cruzi and Trypanosoma rangeli. [PDF]

PLoS ONE, 2017
Trypanosoma cruzi, a human protozoan parasite, is the causative agent of Chagas disease. Currently the species is divided into six taxonomic groups.
Lucila Langoni Naves, Marcos Vinícius da Silva, Emanuella Francisco Fajardo, Raíssa Bernardes da Silva, Fernanda Bernadelli De Vito, Virmondes Rodrigues, Eliane Lages-Silva, Luis Eduardo Ramírez, André Luiz Pedrosa   +8 more
doaj   +1 more source

Caracterização biológica e molecular de cepas de Trypanosoma cruzi isoladas durante o surto de doença de Chagas agudo em Santa Catarina: [dissertação] [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Biotecnologia, Florianópolis, 2010Estudos moleculares e de biologia demonstram que o táxon Trypanosoma cruzi é composto por ...
Pena, Darlene Aparecida
core  

Networks of Indirect Contact Promote Spread of an Environmentally Transmitted Pathogen in a Highly Social Species

Ecology and Evolution, Volume 16, Issue 6, June 2026.
Using behavioral observations and network simulations, we evaluate direct and indirect transmission of the MTBC pathogen M. mungi in banded mongooses. Incorporating intergroup scent marking reveals that environmentally mediated, socially directed pathways can promote spread at low transmissibility, elevating population prevalence even when direct ...
Jack R. Leitch, Neil R. Jordan, John M. Drake, Michael A. Cant, Kathleen A. Alexander   +4 more
wiley   +1 more source