Results 71 to 80 of about 628 (165)

The molecular mechanism of T1AM on weight maintenance and reversing obesity [PDF]

, 2018
The aim of this study aspect was to test the effect of an acute short term pharmacological dose of T1AM in vivo on weight loss, fat loss, and shifts in metabolic substrate utilization from carbohydrate (CHO) to lipid and to compare T1AM’s effects in ...
Rogowski, Michael
core  

WEIGHT LOSS WITH PRESERVED GLUCOSE HOMEOSTASIS DURING CHRONIC TREATMENT OF OBESE MICE WITH 3-IODOTHYRONAMINE (T1AM): ROLE OF THE SIRTUIN FAMILY

, 2013
Objectives: T1AM, an endogenous thyroid hormone derivative, is regarded as a rapid modulator of metabolism. In a recent study we provided the first evidence that subchronic low doses of T1AM increased lipolysis determining significant weight loss without
Reiland H., GHELARDONI, SANDRA, Tonelli M., CHIELLINI, GRAZIA, Scanlan T.S., Carnicelli V., Selen E.S., Assadi Porter F.M., ZUCCHI, RICCARDO, Butz D., Lorenzini L.   +10 more
core   +1 more source

Dosaggio della 3-iodotironamina (T1AM) e sua distribuzione nei tessuti e nel sangue [PDF]

, 2013
Lo scopo di questa tesi è la messa a punto di una metodica per il dosaggio quantitativo delle tironamine, ed in particolare della 3-iodotironammima (T1AM), mediante spettrometria di massa accoppiata ad HPLC.
MARCHINI, MAJA
core  

Caratterizzazione di due modelli cellulari NG 108-15 e U87 MG trattati con 3-iodotironamina (T1AM) e valutazione della presenza dell'aldeide 3-iodotiroacetica come intermedio del catabolismo di T1AM ad acido 3-iodotiroacetico (TA1)

, 2020
Gli ormoni tiroidei sono presenti in due forme: la tetra-iodotironina o tiroxina (T4), che costituisce circa il 90% del totale degli ormoni prodotti e la tri-iodotironina (T3), derivata dalla T4 mediante deionizzazione e che costituisce circa il 10%.
VERLOTTA, SARA
core  

Nongenomic roles of thyroid hormones and their derivatives in adult brain: are these compounds putative neurotransmitters? [PDF]

Front Endocrinol (Lausanne), 2023
Martin JV, Sarkar PK.
europepmc   +1 more source

Evaluation of 3-iodothyronamine (T1AM) in cell preparation, tissue homogenates and biological fluids by HPLC-ESI-MS-MS

, 2009
Mass spectrometry allows a nice insight into the interconversion reactions of the thyroid hormones, working on different types of sample. T1AM is an endogenous compound with chemical features similar to thyroid hormone.
SABA, ALESSANDRO, GHELARDONI, SANDRA, CHIELLINI, GRAZIA, Marchini M, Raffaelli A, ZUCCHI, RICCARDO, Frascarelli S   +6 more
core  

Unveiling the nongenomic actions of thyroid hormones in adult mammalian brain: The legacy of Mary B. Dratman. [PDF]

Front Endocrinol (Lausanne), 2023
Chakrabarti N, Sarkar PK, Ray AK, Martin JV.   +3 more
europepmc   +1 more source

Endogenous TH metabolite 3-iodothyronamine (T1AM) and synthetic thyronamine-like analogues SG-1 and SG-2 induce autophagy in human glioblastoma cells (U-87MG)

, 2017
Endogenous TH metabolite 3-iodothyronamine (T1AM) and recently developed thyronamine-like synthetic analogues SG1 and SG2 have emerged as neuroprotective agents. Autophagy has proved to be an effective therapeutic approach for neurodegenerative diseases.
Giulia Nesi, Francesco Fornai, SABATINI, MARTINA, Martina Sabatini, Lorenza Bellusci, Grazia Chiellini, Paola Lenzi, Riccardo Zucchi, Simona Rapposelli, Leonardo Rossi   +9 more
core   +1 more source

The pleiotropic functionality of endogenous 3-iodothyronamine (T1AM) and synthetic thyronamine-like analogs: a powerful tool to target interlinked diseases such as obesity and neurodegeneration

, 2018
Accumulating evidence has suggested the presence of a strong correlation between obesity and neurodegeneration. Neurodegenerative diseases (NDDs) are characterized by a progressive loss of memory and cognition, which ultimately can lead to death.
Poala Lenzi, Gloria Lazzeri, Federica Fulceri, Stefania Moscato, Giulia Nesi, Francesco Fornai, Martina Sabatini, Massimiliano Runfol, Lorenza Bellusci, Grazia Chiellini, Angelo Mannella, Riccardo Zucchi, Simona Rapposelli, Vittoria Carnicelli   +13 more
core   +1 more source

Thyroid hormone derivates T1AM and 3,5-T2: their effects on rat heart, NG108-15 and U-87 MG cell lines.

, 2020
The term “thyroid hormones”, classically referred to both 3,5,3′-triiodothyronine (T3) and thyroxine (T4), seems nowadays to be simplistic; some T3 and T4 metabolites, particularly 3,5diiodothyronine (3,5-T2) and 3-iodothyronamine (T1AM), are independent
Ginevra Sacripanti
core   +1 more source