Results 21 to 30 of about 137,868 (314)

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients [PDF]

, 2017
There is conflicting evidence on the favorable effects of vitamin D supplementation on metabolic profile in Type 2 diabetes mellitus (T2DM) patients and this might be due to genetic variations in vitamin D receptors (VDRs). Thus, we studied the metabolic
Nasser M. Al-Daghri, Mohammed, A.K., Abdul Khader Mohammed, Hussain, S.D., Omar S. Al-Attas, Ansari, M.G.A, Kaiser Wani, Wani, K., Mohammed Ghouse Ahmed Ansari, Wani, K, Alokail, M.S., Mohammed, A.K, Hussain, S.D, Tripathi, G, Majed S. Alokail, Tripathi, G., Al-Attas, O.S, Sabico, S, Gyanendra Tripathi, Sabico, S., Alokail, M.S, Al-Daghri, N.M, Syed D. Hussain, Shaun Sabico, Al-Attas, O.S., Ansari, M.G.A., Al-Daghri, N.M.   +26 more
core   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

Trimethylamine N-Oxide and Related Metabolites in the Serum and Risk of Type 2 Diabetes in the Chinese Population: A Case-Control Study

Diabetes, Metabolic Syndrome and Obesity, 2023
Shenghong Qi,1,2 Lan Liu,1,2 Shulan He,1,2 Liqun Wang,1,2 Jiangping Li,1,2 Xian Sun1,2 1School of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2The Key Laboratory of Environmental Factors and ...
Qi S, Liu L, He S, Wang L, Li J, Sun X
doaj  

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

Hepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk, Yasaman Vali, Anne Linde Mak, Henrike Galenkamp, Max Nieuwdorp, Bert‐Jan van den Born, Adriaan Georgius Holleboom   +6 more
wiley   +1 more source

Non-pharmacological interventions to reduce the risk of diabetes in people with impaired glucose regulation : a systematic review and economic evaluation [PDF]

, 2012
Background The prevalence of type 2 diabetes mellitus (T2DM) is increasing in the UK and worldwide. Before the onset of T2DM, there are two conditions characterised by blood glucose levels that are above normal but below the threshold for diabetes.
Black, C. (Corrinda), Snaith, Ailsa, Poobalan, A, Poobalan, A. S., A Snaith, Royle, P, G Scotland, Scotland, G., McNamee, P., Gillett, M, Poobalan, A., McNamee, P, Imamura, M., P Royle, N Waugh, Wyness, L., Jick, S, A Poobalan, Waugh, N, Imamura, M. (Mari), Snaith, A., A Brennan, Scotland, G, Snaith, A, S Jick, Brennan, A, M Boroujerdi, Brennan, Alan, Royle, P., Black, C, Gillett, M. (Michael), M Imamura, Black, C., Boroujerdi, M, Jick, S., Royle, Pamela, Waugh, N., Wyness, L, L Wyness, Boroujerdi, M., Imamura, M, Brennan, A., P McNamee, Wyness, Laura, McNamee, Paul, Gillett, M., C Black, Waugh, Norman, M Gillett, Scotland, Graham   +49 more
core   +1 more source

DIABETES MELLITUS: THE MODERN STATE OF THE ISSUE (PART 1)

Паёми Сино, 2019
The authors analyzed numerous scientific studies on the problem of type 2 diabetes mellitus (T2DM), the extent of the spread is causing concern among experts around the world.
M.U. SHAROFOVA, SH.S. SAGDIEVA, S.D. YUSUFI   +2 more
doaj   +1 more source

An emerging protagonist: Sodium Glucose Co-transporters (SGLTs) as a burgeoning target for the treatment of diabetes mellitus

, 2012
Contemporary therapies to rationalize the hyperglycaemia in type 2 diabetes mellitus (T2DM) generally involve insulin-dependent mechanisms and lose their effectiveness as pancreatic b-cell function decreases to a greater extent. The kidney emerges out as
Manju Sharma, Vikas Kumar, Danish Ahmed, Vikas Kumar, Pankaj S Yadav   +4 more
core   +1 more source

Effect of He Qi San on DNA Methylation in Type 2 Diabetes Mellitus Patients with Phlegm-blood Stasis Syndrome

Open Chemistry, 2019
This study was performed to elucidate the potential influence of He Qi San (HQS) on glucose and lipid metabolism in type 2 diabetes mellitus (T2DM) patients with phlegm-blood stasis syndrome (PBSS), and to determine DNA methylation changes.
Shufang Chu, Yinan Zhou, Huilin Li, Hengxia Zhao, Deliang Liu, Xuemei Liu   +5 more
doaj   +1 more source

Insulin initiation and intensification in patients with T2DM for the primary care physician

, 2011
Jeff UngerCatalina Research Institute, Chino, CA, USAAbstract: Type 2 diabetes mellitus (T2DM) is characterized by both insulin resistance and inadequate insulin secretion.
Jeffrey Unger, Unger J
core   +1 more source