Results 31 to 40 of about 177,759 (314)

Preventing type 2 diabetes mellitus in Qatar by reducing obesity, smoking, and physical inactivity: mathematical modeling analyses. [PDF]

, 2019
BACKGROUND: The aim of this study was to estimate the impact of reducing the prevalence of obesity, smoking, and physical inactivity, and introducing physical activity as an explicit intervention, on the burden of type 2 diabetes mellitus (T2DM), using ...
A Abdullah, A Alhazmi, A Pan, Abdulla O. Al-Hamaq, AJ Al-Quwaidhi, C Hawkes, C Willi, D Aune, DP Guh, G Li, J Lindstrom, J Lindstrom, J Lindstrom, JC Lagarias, JM Borys, Julia A. Critchley, Katie G. El-Nahas, L Chen, Laith J. Abu-Raddad, M Chiu, Martin O’Flaherty, NM Abu-Rmeileh, O Saidi, SF Awad, Susanne F. Awad, The Lancet Diabetes E, VS Malik, WC Knowler   +27 more
core   +1 more source

T2DM patients with depression have higher levels of hyperglycemia and cognitive decline than T2DM patients

PLOS ONE, 2022
The cognitive impairment, depression, a decrease in the ability to perform activities of daily living (ADLs), and salivary gland dysfunction, as indicated by the reduction of alpha-amylase activity, have been reported in patients with type 2 diabetes (T2DM).
Savitree Thummasorn, Sopida Apichai, Supat Chupradit, Pornpen Sirisattayawong, Pachpilai Chaiwong, Sirawit Sriwichaiin, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C. Chattipakorn   +8 more
openaire   +3 more sources

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

β-Cell failure in type 2 diabetes: a case of asking too much of too few? [PDF]

, 2013
The islet in type 2 diabetes (T2DM) is characterized by a deficit in β-cells, increased β-cell apoptosis, and extracellular amyloid deposits derived from islet amyloid polypeptide (IAPP). In the absence of longitudinal studies, it is unknown if the low β-
Butler, Peter C, Costes, Safia, Gurlo, Tatyana, Langen, Ralf, Matveyenko, Aleksey V   +4 more
core   +1 more source

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

Hepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk, Yasaman Vali, Anne Linde Mak, Henrike Galenkamp, Max Nieuwdorp, Bert‐Jan van den Born, Adriaan Georgius Holleboom   +6 more
wiley   +1 more source

DIABETES MELLITUS: THE MODERN STATE OF THE ISSUE (PART 1)

Паёми Сино, 2019
The authors analyzed numerous scientific studies on the problem of type 2 diabetes mellitus (T2DM), the extent of the spread is causing concern among experts around the world.
M.U. SHAROFOVA, SH.S. SAGDIEVA, S.D. YUSUFI   +2 more
doaj   +1 more source

Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine [PDF]

, 2019
Type 2 diabetes mellitus (T2DM) is a chronic disease that has reached the levels of a global epidemic. In order to achieve optimal glucose control, it is often necessary to rely on combination therapy of multiple drugs or insulin because uncontrolled ...
Andreozzi, F, Mannino, Gc, Sesti, G
core   +1 more source

FGF23-klotho axis as predictive factors of fractures in type 2 diabetics with early chronic kidney disease [PDF]

, 2020
Background: The aim of our study was to evaluate the relevance of FGF23-klotho axis in the predisposition for bone fractures in type 2 diabetic patients with early chronic kidney disease.
Ana Luísa Ribeiro, Ana Paula Silva, Bacchetta, Bernheim, Block, Daya, Desjardins, Ducy, Ducy, Eduarda Carias, Ferron, Filipa Mendes, Fliser, Fátima Rato, Gutiérrez, Hill, Hu, Isakova, Isakova, Jovanovich, Kazama, Lane, Lee, Levey, Manghat, Mirza, Mirza, Moayeri, Moreno, Moseley, Nélio Santos, Pedro Leão Neves, Pi, Pinkau, Qu, Quarles, Ray, Sanches, Sellmeyer, Shimada, Silva, Silva, Silva, Sitara, Stubbs, Titan, Torres, Urakawa, Wallace, Wang, Wolf, Yilmaz, Zimering   +52 more
core   +1 more source

Assessing microRNA-375 Levels in Type 2 Diabetes Mellitus (T2DM) Patients and T2DM Patients Having First-Degree Relatives With T2DM  [PDF]

, 2020
Abstract Background:The pancreatic islet specific microRNA-375 (miR-375) is reported to be upregulated in diabetes patients suppressing the glucose-induced insulin secretion. In this clinical study we aimed to assess the significance of miR-375 among type 2 diabetes mellitus (T2DM) patients and their first-degree relatives with normal glucose ...
Wu Xu, Li Yashan, Man Baohua, Li Dexuan
openaire   +1 more source

Weight losses with low energy formula diets in obese patients with and without type 2 diabetes: Systematic review and meta-analysis [PDF]

, 2016
Aim: To provide a systematic review, of published data, to compare weight losses following very low calorie (<800 kcal per day VLCD) or low-energy liquid-formula (>800 kcal per day LELD) diets, in people with and without type 2 diabetes mellitus ...
Harris, L., Lean, M.E.J., Leslie, W.S., Taylor, R.   +3 more
core   +1 more source