Results 41 to 50 of about 12,333 (188)

Piericidin A1 Blocks Yersinia Ysc Type III Secretion System Needle Assembly

mSphere, 2017
The type III secretion system (T3SS) is a bacterial virulence factor expressed by dozens of Gram-negative pathogens but largely absent from commensals.
Jessica M. Morgan, Miles C. Duncan, Kevin S. Johnson, Andreas Diepold, Hanh Lam, Allison J. Dupzyk, Lexi R. Martin, Weng Ruh Wong, Judith P. Armitage, Roger G. Linington, Victoria Auerbuch   +10 more
doaj   +1 more source

Phylogenetic analysis of a gene cluster encoding an additional, rhizobial-like type III secretion system that is narrowly distributed among Pseudomonas syringae strains

BMC Microbiology, 2012
Background The central role of Type III secretion systems (T3SS) in bacteria-plant interactions is well established, yet unexpected findings are being uncovered through bacterial genome sequencing.
Gazi Anastasia D, Sarris Panagiotis F, Fadouloglou Vasiliki E, Charova Spyridoula N, Mathioudakis Nikolaos, Panopoulos Nicholas J, Kokkinidis Michael   +6 more
doaj   +1 more source

Oleanolic acid induces the type III secretion system of Ralstonia solanacearum

Frontiers in Microbiology, 2015
Ralstonia solanacearum, the causal agent of bacterial wilt, can naturally infect a wide range of host plants. The type III secretion system (T3SS) is a major virulence determinant in this bacterium.
Dousheng eWu, Wei eDing, Yong eZhang, Xuejiao eLiu, Liang eYang   +4 more
doaj   +1 more source

Yersinia actively downregulates type III secretion and adhesion at higher cell densities. [PDF]

PLoS Pathog
The T3SS injectisome is used by Gram-negative bacteria, including important pathogens, to manipulate eukaryotic target cells by injecting effector proteins.
Ermoli F, Malengo G, Spahn C, Brianceau C, Glatter T, Diepold A.   +5 more
europepmc   +2 more sources

T3DB: an integrated database for bacterial type III secretion system

BMC Bioinformatics, 2012
Background Type III Secretion System (T3SS), which plays important roles in pathogenesis or symbiosis, is widely expressed in a variety of gram negative bacteria. However, lack of unique nomenclature for T3SS genes has hindered T3SS related research.
Wang Yejun, Huang He, Sun Ming’an, Zhang Qing, Guo Dianjing   +4 more
doaj   +1 more source

Modulation of Host Cell Processes by T3SS Effectors

, 2018
Two of the enteric Escherichia coli pathotypes-enteropathogenic E. coli (EPEC) and enterohaemorrhagic E. coli (EHEC)-have a conserved type 3 secretion system which is essential for virulence. The T3SS is used to translocate between 25 and 50 bacterial proteins directly into the host cytosol where they manipulate a variety of host cell processes to ...
Shenoy, AR, Furniss, RCD, Goddard, PJ, Clements, A   +3 more
openaire   +4 more sources

Identification and characterization of putative Aeromonas spp. T3SS effectors

PLOS ONE, 2019
AbstractThe genetic determinants of bacterial pathogenicity are highly variable between species and strains. However, a factor that is commonly associated with virulent Gram-negative bacteria, including manyAeromonasspp., is the type 3 secretion system (T3SS), which is used to inject effector proteins into target eukaryotic cells.
Rangel, Luiz Thiberio, Marden, Jeremiah, Colston, Sophie, Setubal, João Carlos, Graf, Joerg, Gogarten, J. Peter   +5 more
openaire   +3 more sources

Action of Multiple Cell Wall–Degrading Enzymes Is Required for Elicitation of Innate Immune Responses During Xanthomonas oryzae pv. oryzae Infection in Rice

Molecular Plant-Microbe Interactions, 2016
Xanthomonas oryzae pv. oryzae secretes a number of plant cell wall–degrading enzymes (CWDEs) whose purified preparations induce defense responses in rice. These defense responses are suppressed by X. oryzae pv. oryzae using type 3 secretion system (T3SS)
Lavanya Tayi, Roshan Maku, Hitendra Kumar Patel, Ramesh V. Sonti   +3 more
doaj   +1 more source

Ancient co-option of an amino acid ABC transporter locus in Pseudomonas syringae for host signal-dependent virulence gene regulation.

PLoS Pathogens, 2020
Pathogenic bacteria frequently acquire virulence traits via horizontal gene transfer, yet additional evolutionary innovations may be necessary to integrate newly acquired genes into existing regulatory pathways.
Qing Yan, Conner J Rogan, Yin-Yuin Pang, Edward W Davis, Jeffrey C Anderson   +4 more
doaj   +1 more source

IscR is essential for yersinia pseudotuberculosis type III secretion and virulence. [PDF]

PLoS Pathogens, 2014
Type III secretion systems (T3SS) are essential for virulence in dozens of pathogens, but are not required for growth outside the host. Therefore, the T3SS of many bacterial species are under tight regulatory control. To increase our understanding of the
Halie K Miller, Laura Kwuan, Leah Schwiesow, David L Bernick, Erin Mettert, Hector A Ramirez, James M Ragle, Patricia P Chan, Patricia J Kiley, Todd M Lowe, Victoria Auerbuch   +10 more
doaj   +1 more source