Results 91 to 100 of about 8,918 (214)

The breadth and molecular basis of Hcp-driven type six secretion system (T6SS) effector delivery

, 2021
The type VI secretion system (T6SS) is a bacterial nanoscale weapon that delivers toxins into prey ranging from bacteria and fungi to animal hosts. The cytosolic contractile sheath of the system wraps around stacked hexameric rings of Hcp proteins, which
Amin, Himani, Zlotkin, David, Sophie A. Howard, Himani Amin, Furniss,, R Christopher D, R. D. Costa,, Tiago, A. I. Mavridou,, Despoina, Bonini, Dora, Paracuellos,, Patricia, Patricia Paracuellos, Filloux, Alain, Alain Filloux, Asaf Levy, Costa, Tiago R. D., Howard, Sophie A., Despoina A. I. Mavridou, Amin,, Himani, Levy, Asaf, Furniss, R. Christopher D.,, Howard, Sophie A, Mavridou, Despoina A. I., Paracuellos, Patricia, Tiago R. D. Costa, Dora Bonini, Bonini,, Dora, R. Christopher D. Furniss, David Zlotkin   +26 more
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T6SS in plant pathogens: unique mechanisms in complex hosts

Infection and Immunity
ABSTRACT Type VI secretion systems (T6SSs) are complex molecular machines that allow bacteria to deliver toxic effector proteins to neighboring bacterial and eukaryotic cells. Although initial work focused on the T6SS as a virulence mechanism of human pathogens, the field shifted to examine the use of ...
Lexie M. Matte, Abigail V. Genal, Emily F. Landolt, Elizabeth S. Danka   +3 more
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Virulence of a T6SS Campylobacter jejuni chicken isolate from North Romania [PDF]

BMC Research Notes, 2019
In this study we have investigated the in vitro and in vivo virulence characteristics of a new T6SS positive Campylobacter jejuni chicken isolate (SV12) originating from a poultry population in North Romania. A detailed phenotypic characterization was performed and compared to the T6SS negative C. jejuni 81-176 wild strain.Our results indicate that the
Vlad A. Ungureanu, Alexandros Ch. Stratakos, Ozan Gundogdu, Lavinia Stef, Ioan Pet, Elena Pet, Nicolae Pacala, Nicolae Corcionivoschi   +7 more
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OxyR directly activates T6SS-4 expression.

, 2015
A. OxyR binds the T6SS-4 promoter. Biotin-labeled probe or its mutant was incubated with OxyR. The protein-DNA complexes were detected by streptavidin-conjugated HRP and chemiluminescent substrate.
Yunhong Song (637619), Yao Wang (102387), Weipeng Zhang (551437), Wenhan Zhu (227950), Zhao-Qing Luo (227963), Tietao Wang (637621), Lei Zhang (38117), Xihui Shen (229806), Meiru Si (675416), Fen Gao (764444), Gehong Wei (420301)   +10 more
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The Pseudomonas aeruginosa T6SS delivers a periplasmic toxin that disrupts bacterial cell morphology [PDF]

, 2019
The type VI secretion system (T6SS) is crucialin interbacterial competition and is avirulence determinant ofmany Gram-negative bacteria. Several T6SS effectorsarecovalently fused to secreted T6SS structural components such asthe VgrG spike for
Bullen, NP, Hayward, RD, Nolan, LM, Wood, TE, Freemont, PS, Yau, HCL, Filloux, Alain, Hachani, A, Manoli, E, Whitney, JC, Vollmer, W, Howard, SA, Forster, A   +12 more
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Chitin-induced T6SS in Vibrio cholerae is dependent on ChiS activation

Microbiology, 2018
Vibrio cholerae regularly colonizes the chitinous exoskeleton of crustacean shells in the aquatic region. The type 6 secretion system (T6SS) in V. cholerae is an interbacterial killing device. This system is thought to provide a competitive advantage to V. cholerae in a polymicrobial community of the aquatic region under nutrient-poor conditions.
Rhishita, Chourashi, Suman, Das, Debarpan, Dhar, Keinosuke, Okamoto, Asish K, Mukhopadhyay, Nabendu Sekhar, Chatterjee   +5 more
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Pantoea ananatis Utilizes a Type VI Secretion System for Pathogenesis and Bacterial Competition

Molecular Plant-Microbe Interactions, 2015
Type VI secretion systems (T6SSs) are a class of macromolecular machines that are recognized as an important virulence mechanism in several gram-negative bacteria.
Divine Y. Shyntum, Jacques Theron, Stephanus N. Venter, Lucy N. Moleleki, Ian K. Toth, Teresa A. Coutinho   +5 more
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Two Type VI Secretion Systems of Enterobacter cloacae Are Required for Bacterial Competition, Cell Adherence, and Intestinal Colonization

Frontiers in Microbiology, 2020
Enterobacter cloacae has emerged as an opportunistic pathogen in healthcare-associated infections. Analysis of the genomic sequences of several E. cloacae strains revealed the presence of genes that code for expression of at least one type VI secretion ...
Jorge Soria-Bustos, Jorge Soria-Bustos, Miguel A. Ares, Carlos A. Gómez-Aldapa, Jorge A. González-y-Merchand, Jorge A. Girón, Miguel A. De la Cruz   +6 more
doaj   +1 more source

Divergent control of RpoN on H2-T6SS and H3-T6SS.

, 2013
The expression of H2-T6SS (A), H3-T6SS left (B), and H3-T6SS right (C) after 7 hours (A), or 9 hours (B & C) of growth at 37°C in the WT strain (blue bars), in a PAO1ΔrpoN mutant complemented strain (green bars, PAO6360 strain) or the PAO1 ΔrpoN mutant ...
Thibault G. Sana (474771), Chantal Soscia (474772), Steve Garvis (474774), Céline M. Tonglet (474773), Sophie Bleves (474775)   +4 more
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Subtle variation within conserved effector operon gene products contributes to T6SS-mediated killing and immunity. [PDF]

, 2017
Type VI secretion systems (T6SS) function to deliver lethal payloads into target cells. Many studies have shown that protection against a single, lethal T6SS effector protein requires a cognate antidote immunity protein, both of which are often encoded ...
Harry L. T. Mobley, Kevin Zhu, Haley L. Hershey, Stephanie D. Himpsl, Harry L T Mobley, Christopher J. Alteri, Stephanie D Himpsl, Ninette Musili, Christopher J Alteri, Jessa E. Miller, Haley L Hershey, Jessa E Miller   +11 more
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