Results 111 to 120 of about 8,918 (214)

Sfa2 negatively controls H2-T6SS expression while H3-T6SS expression is Sfa-independent.

, 2013
The expression of H3-T6SS left (A), H3-T6SS right (B), and H2-T6SS (C) after 6 hours of growth after 9 hours (A & B) or 7 hours (C) at 37°C in the WT strain (blue bars), in a PAO1sfa2 mutant (red bars), and in a PAO1sfa3 mutant (green bars).
Thibault G. Sana (474771), Chantal Soscia (474772), Steve Garvis (474774), Céline M. Tonglet (474773), Sophie Bleves (474775)   +4 more
core   +1 more source

Immunity proteins of dual nuclease T6SS effectors function as transcriptional repressors

, 2021
Bacteria utilize type VI secretion system (T6SS) to deliver antibacterial toxins to target co‐habiting bacteria. Here, we report that Burkholderia gladioli strain NGJ1 deploys certain T6SS effectors (TseTBg), having both DNase and RNase activities to ...
Kumar, Rahul, Jha, Gopaljee, Joyati Das, Magotra, Ankita, Sunil Kumar Yadav, Yadav, Sunil Kumar, Pradhan, Amrita, Das, Joyati, Gopaljee Jha, Ghosh, Srayan, Aiswarya Krishnan, Mamta Sharma, Ankita Magotra, Srayan Ghosh, Sharma, Mamta, Rahul Kumar, Amrita Pradhan, Krishnan, Aiswarya   +17 more
core   +1 more source

Twists, turns and jumps: T6SS evolution within species

Trends in Microbiology
The type VI secretion system mediates interbacterial antagonism between Gram-negative bacteria through delivery of toxic effector proteins. A recent comprehensive genomic analysis by Habich et al. reveals interesting features of the evolution of T6SSs and their corresponding effectors in Pseudomonas aeruginosa, raising questions about functional ...
Beth A. Shen, S. Brook Peterson, Joseph D. Mougous   +2 more
openaire   +2 more sources

T6SS-mediated bacterial antagonism in the classroom

The study of bacterial antagonism, and specifically Type VI secretion System (T6SS)-mediated antagonism, has gained momentum over the last decade in research laboratories across the world. The T6SS is a molecular machine that mediates interbacterial antagonism as well as interactions with the host in the case of pathogenic or commensal organisms. Here,
Alejandro Tejada-Arranz, Peter Ringel, Lin Lin, Marek Basler   +3 more
openaire   +1 more source

H2-T6SS-dependent Cu²⁺ transport system is important for competitive growth and virulence.

, 2019
(A) OprC and Azu mediate H2-T6SS-dependent intrabacterial competition. The indicated strains were grown in LB medium supplemented with 0.25 mM EDTA for 6 h.
Tietao Wang (637621), Linghui Xu (6295400), Yuying Han (8067419), Qiong Liu (299371), Gukui Chen (6706658), Min Wu (41570), Haihua Liang (1993753), Qinqin Pu (2831669), Yani Zhang (446928)   +8 more
core   +1 more source

Genetic organization of T6SS loci.

, 2013
Selected genomes of sequenced Acinetobacter strains were probed for the presence of T6SS genes, with those genes predicted to be involved in T6SS colored and identified below the figure. Gene accession numbers are provided in Table 1.
Jeremy A. Iwashkiw (159926), Brent S. Weber (159930), Eric P. Skaar (112846), Brittany L. Mortensen (112834), Stefan Pukatzki (277002), Mario F. Feldman (159969), Sarah T. Miyata (277001)   +6 more
core   +1 more source

H2-T6SS and H3-T6SS are coregulated by QS.

, 2013
(A) Expression patterns of the H2-T6SS, H3-T6SS left, and H3-T6SS right lacZ transcriptional fusions from the WT PAO1 strain (PAO1TS2, PAO1TS19 and PAO1TS20 respectively) and of a control strain (PAO1Z).
Thibault G. Sana (474771), Chantal Soscia (474772), Steve Garvis (474774), Céline M. Tonglet (474773), Sophie Bleves (474775)   +4 more
core   +1 more source

Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources?

BMC Genomics, 2009
Background The availability of hundreds of bacterial genomes allowed a comparative genomic study of the Type VI Secretion System (T6SS), recently discovered as being involved in pathogenesis.
Vandenbrouck Yves, Berthod Jérémie, Fichant Gwennaële, Boyer Frédéric, Attree Ina   +4 more
doaj   +1 more source

Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors

Journal of Biological Engineering
Abstract Background Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS), to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine capable of delivering toxic effectors into neighboring cells, providing advantages in bacterial interactions.
Pérez-Lorente, Alicia Isabel, Araujo-Garrido, Mario, De-Vicente-Moreno, Antonio, Romero-Hinojosa, Diego Francisco, Molina-Santiago, Carlos   +4 more
openaire   +5 more sources

Capsular polysaccharide restrains type VI secretion in Acinetobacter baumannii

eLife
The type VI secretion system (T6SS) is a sophisticated, contact-dependent nanomachine involved in interbacterial competition. To function effectively, the T6SS must penetrate the membranes of both attacker and target bacteria.
Nicolas Flaugnatti, Loriane Bader, Mary Croisier-Coeytaux, Melanie Blokesch   +3 more
doaj   +1 more source