Results 101 to 110 of about 8,552 (215)

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

High genetic diversity and different type VI secretion systems in Enterobacter species revealed by comparative genomics analysis

BMC Microbiology
The human-pathogenic Enterobacter species are widely distributed in diverse environmental conditions, however, the understanding of the virulence factors and genetic variations within the genus is very limited.
Mu Peng, Weiyuan Lin, Aifen Zhou, Zhihui Jiang, Fangzhen Zhou, Zhiyong Wang   +5 more
doaj   +1 more source

Hospital‐Based Cross‐Sectional Study of Burkholderia pseudomallei Seroreactivity Among Febrile Patients in Northernmost Vietnam: Near‐Neighbor Bloodstream Isolates, Environmental Correlates, and Spatial Clustering

GeoHealth, Volume 10, Issue 6, June 2026.
Abstract Melioidosis is a potentially fatal tropical disease caused by the environmentally mediated bacterium, Burkholderia pseudomallei. In Vietnam, melioidosis is not nationally reportable and little is known regarding its epidemiology and distribution in the northernmost mountainous provinces.
Morgan C. Metrailer, Tran Thi Le Quyen, Khang Van Pham, Tan Minh Luong, Treenate Jiranantasak, Andrew P. Bluhm, Frank J. Tuozzo II, Thi Thu Ha Hoang, Minh Hoa Luong, Bich Ngoc Do, Thanh Hai Pham, Madison E. A. Harman, Michael H. Norris, Trinh Thanh Trung, Jason K. Blackburn   +14 more
wiley   +1 more source

Contact-dependent preemptive antagonism is dependent on the T6SS.

, 2013
(A) A Dienes line (black arrows) forms between two different wild-type isolates, HI4320 and BB2000 (strain A and B kill each other). Loss of the T6SS (ΔT6) in either isolate by disruption of PMI0742 does not affect the discriminatory Dienes line (strain ...
Jonathon R. Lindner (454436), Samuel W. Straight (419303), Stephanie D. Himpsl (454434), Jessa E. Miller (454438), Harry L. T. Mobley (145288), Shannon R. Pickens (454435), Peter D. Arno (454439), Christopher J. Alteri (259472), Jonathan S. Zora (454437)   +8 more
core   +1 more source

Guardians or Gateways? The Intricate Relationship Between Plant Cell Walls and Pathogenic Xanthomonas

Molecular Plant Pathology, Volume 27, Issue 6, June 2026.
An overview of the intricate interactions between Xanthomonas and the plant cell wall during the infection process. ABSTRACT Plants have evolved a complex cell wall (CW) providing support and protection against environmental constraints, including constant attacks from pests and pathogens.
Charlotte Gaudin, Marie‐Agnès Jacques, Nicolas W. G. Chen   +2 more
wiley   +1 more source

Genetic organization of T6SS in Enterobacter.

, 2013
(A) and (B) show genetic organization of the two T6SS clusters commonly found in Enterobacter. ENHKU01 and ATCC13047 contain both T6SS, and EcWSU1, SDM and LF7a have one of the two, and other Enterobacter have none.
Jing-Wei Jiang (457852), Karl Ming-Kar Chung (457851), Frederick Chi-Ching Leung (270946), Wing-Yee Liu (457849), Chi-Fat Wong (457850)   +4 more
core   +1 more source

Table_2_Identification and distribution of new candidate T6SS effectors encoded in Salmonella Pathogenicity Island 6.xlsx

, 2023
The type VI secretion system (T6SS) is a contact-dependent contractile multiprotein apparatus widely distributed in Gram-negative bacteria. These systems can deliver different effector proteins into target bacterial and/or eukaryotic cells, contributing ...
Carlos A. Santiviago (12069677), Fernando A. Amaya (5351576), David Pezoa (412601), Carlos J. Blondel (7208465), Paloma Bustamante (16841967)   +4 more
core   +1 more source

Twists, turns and jumps: T6SS evolution within species

Trends in Microbiology
The type VI secretion system mediates interbacterial antagonism between Gram-negative bacteria through delivery of toxic effector proteins. A recent comprehensive genomic analysis by Habich et al. reveals interesting features of the evolution of T6SSs and their corresponding effectors in Pseudomonas aeruginosa, raising questions about functional ...
Beth A. Shen, S. Brook Peterson, Joseph D. Mougous   +2 more
openaire   +2 more sources

Sfa2 negatively controls H2-T6SS expression while H3-T6SS expression is Sfa-independent.

, 2013
The expression of H3-T6SS left (A), H3-T6SS right (B), and H2-T6SS (C) after 6 hours of growth after 9 hours (A & B) or 7 hours (C) at 37°C in the WT strain (blue bars), in a PAO1sfa2 mutant (red bars), and in a PAO1sfa3 mutant (green bars).
Thibault G. Sana (474771), Chantal Soscia (474772), Steve Garvis (474774), Céline M. Tonglet (474773), Sophie Bleves (474775)   +4 more
core   +1 more source

Role of Klebsiella pneumoniae Type VI secretion system (T6SS) in long-term gastrointestinal colonization

, 2022
International audienceAbstract Type VI secretion systems (T6SS), recently described in hypervirulent K. pneumoniae (hvKp) strains , are involved in bacterial warfare but their role in classical clinical strains (cKp) has been little investigated .
Nakusi, Laurence, Miquel, Sylvie, Theil, Sébastien, Rendueles, Olaya, Merciecca, Thomas, Bornes, Stéphanie, Forestier, Christiane   +6 more
core   +1 more source