Results 121 to 130 of about 8,918 (214)

Evolutionary Constraints of Defense Against T6SS Attack in E. Coli [PDF]

The Type VI secretion system (T6SS) is a toxin-tipped molecular spear used by Gram-negative bacteria to eliminate competitors in the environment. While the structure and function of the T6SS are well understood, less is known about how targeted bacteria ...
MacGillivray, Kathryn A., PhD
core  

The T6SS and primary effector operon are required for killing.

, 2013
The T6SS and primary effector operon are required for killing.
Jonathon R. Lindner (454436), Samuel W. Straight (419303), Stephanie D. Himpsl (454434), Jessa E. Miller (454438), Harry L. T. Mobley (145288), Shannon R. Pickens (454435), Peter D. Arno (454439), Christopher J. Alteri (259472), Jonathan S. Zora (454437)   +8 more
core   +1 more source

Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome

Frontiers in Microbiology
IntroductionBacteroides fragilis (Bf)’s T6SS locus has been characterized and shown to have functional activity in competition experiments. It has been demonstrated that symbiont nontoxigenic Bf strains have a more effective “weapon” effect on pathogenic Bf, which is realized through the activity of effector-immune (E-I) protein pairs.
Natalya B. Zakharzhevskaya, Olga Yu Shagaleeva, Daria A. Kashatnikova, Daria A. Kashatnikova, Anton O. Goncharov, Anton O. Goncharov, Daria V. Evsyutina, Dmitry A. Kardonsky, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Viktoria D. Kazakova, Irina V. Kolesnikova, Ivan O. Butenko, Anna A. Vanyushkina, Svetlana V. Smirnova, Andrei V. Chaplin, Andrei V. Chaplin, Boris A. Efimov, Boris A. Efimov   +18 more
openaire   +3 more sources

Genetic organization of T6SS in Enterobacter.

, 2013
(A) and (B) show genetic organization of the two T6SS clusters commonly found in Enterobacter. ENHKU01 and ATCC13047 contain both T6SS, and EcWSU1, SDM and LF7a have one of the two, and other Enterobacter have none.
Jing-Wei Jiang (457852), Karl Ming-Kar Chung (457851), Frederick Chi-Ching Leung (270946), Wing-Yee Liu (457849), Chi-Fat Wong (457850)   +4 more
core   +1 more source

T2SS and its secreted substrates ZmpA and ZmpB are required to delay phagolysosomal fusion and for bacterial survival in macrophages in a T6SS-independent manner.

, 2012
A. Alignment of the predicted ZmpA and ZmpB from B. cenocepacia with Zmp1 from Mycobacterium tuberculosis. The active site consensus is indicated in bold. B. Macrophages were infected with B. cenocepacia MH1K-RFP (Red) at an MOI of 50 for 4 h.
Daniel F. Aubert (148581), Miguel A. Valvano (148588), Roberto Rosales-Reyes (148577), Jennifer S. Tolman (148583), Amal O. Amer (148585)   +4 more
core   +1 more source

Contact-dependent preemptive antagonism is dependent on the T6SS.

, 2013
(A) A Dienes line (black arrows) forms between two different wild-type isolates, HI4320 and BB2000 (strain A and B kill each other). Loss of the T6SS (ΔT6) in either isolate by disruption of PMI0742 does not affect the discriminatory Dienes line (strain ...
Jonathon R. Lindner (454436), Samuel W. Straight (419303), Stephanie D. Himpsl (454434), Jessa E. Miller (454438), Harry L. T. Mobley (145288), Shannon R. Pickens (454435), Peter D. Arno (454439), Christopher J. Alteri (259472), Jonathan S. Zora (454437)   +8 more
core   +1 more source

The nucleoid protein HU positively regulates the expression of type VI secretion systems in Enterobacter cloacae

mSphere
Enterobacter cloacae is an emerging pathogen isolated in healthcare-associated infections. A major virulence factor of this bacterium is the type VI secretion system (T6SS). The genome of E. cloacae harbors two T6SS gene clusters (T6SS-1 and T6SS-2), and
Gabriela Hernández-Martínez, Miguel A. Ares, Roberto Rosales-Reyes, Jorge Soria-Bustos, Jorge Antonio Yañez-Santos, María L. Cedillo, Jorge A. Girón, Ygnacio Martínez-Laguna, Fenfei Leng, J. Antonio Ibarra, Miguel A. De la Cruz   +10 more
doaj   +1 more source

Type VI secretion system degeneration accelerates intestinal epithelial cell death in Escherichia coli O157:H7.

PLoS Pathogens
The type VI secretion system (T6SS) is a specific protein secretion apparatus that contributes to bacterial virulence. Enterohemorrhagic Escherichia coli O157:H7 (EHEC) harbors multiple prophages and can cause severe human diseases worldwide.
Zhibin Sun, Chao Dong, Pengcheng Zhou, Quanquan Guan, Zhongli Cui, Yankai Xia, Yu-Feng Yao   +6 more
doaj   +1 more source

Functional characterisation of a Pseudomonas aeruginosa antibacterial molecular weapon: the H3-T6SS and its cognate toxins

P. aeruginosa possesses several molecular tools to colonize and survive in a host, such as the type VI secretion system (T6SS) – a contractile molecular syringe that delivers effectors and toxins into eukaryotic and prokaryotic cells. P.
Teo, Zoe ZiYi
core  

Issue Information

mLife, Volume 5, Issue 4, Page i-iv, August 2026.
wiley   +1 more source