Results 121 to 130 of about 8,552 (215)

Subtle variation within conserved effector operon gene products contributes to T6SS-mediated killing and immunity. [PDF]

, 2017
Type VI secretion systems (T6SS) function to deliver lethal payloads into target cells. Many studies have shown that protection against a single, lethal T6SS effector protein requires a cognate antidote immunity protein, both of which are often encoded ...
Harry L. T. Mobley, Kevin Zhu, Haley L. Hershey, Stephanie D. Himpsl, Harry L T Mobley, Christopher J. Alteri, Stephanie D Himpsl, Ninette Musili, Christopher J Alteri, Jessa E. Miller, Haley L Hershey, Jessa E Miller   +11 more
core   +1 more source

Capsular polysaccharide restrains type VI secretion in Acinetobacter baumannii

eLife
The type VI secretion system (T6SS) is a sophisticated, contact-dependent nanomachine involved in interbacterial competition. To function effectively, the T6SS must penetrate the membranes of both attacker and target bacteria.
Nicolas Flaugnatti, Loriane Bader, Mary Croisier-Coeytaux, Melanie Blokesch   +3 more
doaj   +1 more source

Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors

Journal of Biological Engineering
Abstract Background Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS), to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine capable of delivering toxic effectors into neighboring cells, providing advantages in bacterial interactions.
Pérez-Lorente, Alicia Isabel, Araujo-Garrido, Mario, De-Vicente-Moreno, Antonio, Romero-Hinojosa, Diego Francisco, Molina-Santiago, Carlos   +4 more
openaire   +5 more sources

Issue Information

mLife, Volume 5, Issue 4, Page i-iv, August 2026.
wiley   +1 more source

P. aeruginosa T6SS minicell

, 2017
Pseudomonas JT1599Grid box YWC247<strong>Tilt Series Date:</strong> 2017-04-14</p> <strong>Data Taken By:</strong> Yi-Wei Chang</p> <strong>Species / Specimen:</strong> Pseudomonas aeruginosa</p> < ...
Chang, Yi-Wei
core   +1 more source

The nucleoid protein HU positively regulates the expression of type VI secretion systems in Enterobacter cloacae

mSphere
Enterobacter cloacae is an emerging pathogen isolated in healthcare-associated infections. A major virulence factor of this bacterium is the type VI secretion system (T6SS). The genome of E. cloacae harbors two T6SS gene clusters (T6SS-1 and T6SS-2), and
Gabriela Hernández-Martínez, Miguel A. Ares, Roberto Rosales-Reyes, Jorge Soria-Bustos, Jorge Antonio Yañez-Santos, María L. Cedillo, Jorge A. Girón, Ygnacio Martínez-Laguna, Fenfei Leng, J. Antonio Ibarra, Miguel A. De la Cruz   +10 more
doaj   +1 more source

T6SS-dependent competition among V. cholerae isolates.

, 2013
(A–C) Smooth V. cholerae isolates successfully competed with each other and outcompeted the rough isolates in a T6SS-dependent manner. All combinations among the isolates and their isogenic vasK mutants were tested in a killing assay: Predator- and prey ...
Jorge Duran-Gonzalez (301560), Oscar Sosa (301558), Teresa M. Brooks (301556), Maya Kitaoka (301555), David Silva (301559), Jessica Moloney (301557), Daniel Unterweger (109620), Daniele Provenzano (301561), Verena Bachmann (154491), Stefan Pukatzki (277002), Sarah T. Miyata (277001)   +10 more
core   +1 more source

TssW-PpkA-Fha axis controls the positioning and initiation of the type VI secretion system in Acidovorax citrulli

mBio
Understanding how bacteria spatially regulate their molecular weaponry is key to unraveling their virulence and survival strategies in competitive ecosystems.
Tong-Tong Pei, Xing-Yu Wang, Zi-Yan Ye, Yi-Qiu Zhang, Jing-Tong Su, Han Luo, Ya-Jie Zhao, Hao-Yu Zheng, Zhu Si, Ying An, Xiaoye Liang, Tao Dong   +11 more
doaj   +1 more source

Investigating the type VI secretion system in diazotrophic, grass endophyte Azoarcus sp. strain BH72

, 2014
The predicted T6SS gene clusters found within the genome of Azoarcus sp. BH72 were examined and found to share characteristics of T6SSs described in literature. The presence of Hcp in culture supernatants confirmed T6SS activity. Furthermore, deletion of
Dinse, Theresa
core  

MIXing up T6SS effectors [PDF]

Nature Reviews Microbiology, 2015
openaire   +1 more source