Results 11 to 20 of about 9,692 (159)
T6SS intraspecific competition orchestrates Vibrio cholerae genotypic diversity [PDF]
International microbiology : the official journal of the Spanish Society for Microbiology, 2017 Vibrio cholerae is a diverse species that inhabits a wide range of environments from copepods in brackish waterto the intestines of humans. In order to remain competitive, V.
Benjamin Kostiuk +3 more
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An Overview of Anti-Eukaryotic T6SS Effectors [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 The type VI secretion system (T6SS) is a transmembrane multiprotein nanomachine employed by many Gram-negative bacterial species to translocate, in a contact-dependent manner, effector proteins into adjacent prokaryotic or eukaryotic cells. Typically, the T6SS gene cluster encodes at least 13 conserved core components for the apparatus assembly and ...
Monjaras Feria, Julia +1 more
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T6SS: killing two bugs with one stone
Trends in Microbiology, 2022 Bacteria deploy the type VI secretion system (T6SS) to inject effectors into bacterial rivals. Contrary to the prevailing model, a recent study (Le et al.) expands the target range of the T6SS by demonstrating that it delivers and potentializes a peptidoglycan-targeting bifunctional toxin into Gram-positive bacteria.
Dukas Jurėnas, Eric Cascales
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Differential Expression of Paraburkholderia phymatum Type VI Secretion Systems (T6SS) Suggests a Role of T6SS-b in Early Symbiotic Interaction [PDF]
Frontiers in Plant Science, 2021 Paraburkholderia phymatum STM815, a rhizobial strain of the Burkholderiaceae family, is able to nodulate a broad range of legumes including the agriculturally important Phaseolus vulgaris (common bean). P. phymatum harbors two type VI Secretion Systems (T6SS-b and T6SS-3) in its genome that contribute to its high interbacterial competitiveness in vitro
Hug, Sebastian +6 more
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T6SS: A Key to Pseudomonas’s Success in Biocontrol?
Microorganisms, 2023 Bacteria from the genus Pseudomonas have been extensively studied for their capacity to act as biological control agents of disease and pests and for their ability to enhance and promote crop production in agricultural systems. While initial research primarily focused on the human pathogenic bacteria Pseudomonas aeruginosa, recent studies indicate the ...
Edwin D. Navarro-Monserrat +1 more
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Engineering a customizable antibacterial T6SS‐based platform in Vibrio natriegens [PDF]
EMBO reports, 2021 ABSTRACTBacterial pathogens are a major risk to human, animal, and plant health. To counteract the spread of antibiotic resistance, alternative antibacterial strategies are urgently needed. Here, we constructed a proof-of-concept customizable, modular, and inducible antibacterial toxin delivery platform. By engineering a type VI secretion system (T6SS)
Jana, Biswanath +2 more
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Endogenous membrane stress induces T6SS activity in Pseudomonas aeruginosa [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance In this study, we applied a CRISPR interference approach to knock down expression of essential genes involved in cell envelope biogenesis and determined if this can trigger Pseudomonas aeruginosa T6SS apparatus assembly.
Anne-Sophie Stolle +3 more
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A Visual Assay to Monitor T6SS-mediated Bacterial Competition [PDF]
Journal of Visualized Experiments, 2013 Type VI secretion systems (T6SSs) are molecular nanomachines allowing Gram-negative bacteria to transport and inject proteins into a wide variety of target cells(1,2). The T6SS is composed of 13 core components and displays structural similarities with the tail-tube of bacteriophages(3).
Hachani, A, Lossi, NS, Filloux, A
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T6SS Accessory Proteins, Including DUF2169 Domain-Containing Protein and Pentapeptide Repeats Protein, Contribute to Bacterial Virulence in T6SS Group_5 of Burkholderia glumae BGR1 [PDF]
Plants, 2021 Burkholderia glumae are bacteria pathogenic to rice plants that cause a disease called bacterial panicle blight (BPB) in rice panicles. BPB, induced by B. glumae, causes enormous economic losses to the rice agricultural industry. B. glumae also causes bacterial disease in other crops because it has various virulence factors, such as toxins, proteases ...
Namgyu Kim +5 more
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NrtR Mediated Regulation of H1-T6SS in Pseudomonas aeruginosa
Microbiology Spectrum, 2022 NrtR is a Nudix-related transcriptional regulator and controls the NAD cofactor biosynthesis in bacteria. P. aeruginosa NrtR binds to the intergenic region between nadD2 and pncA to repress the expression of the two operons, therefore controlling the NAD biosynthesis ...
Xinxin Zhang +9 more
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