Results 21 to 30 of about 9,692 (159)

T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation [PDF]

International Journal of Molecular Sciences, 2021
The bacterial type VI secretion system (T6SS) is a protein secretion apparatus widely distributed in Gram-negative bacterial species. Many bacterial pathogens employ T6SS to compete with the host and to coordinate the invasion process. The T6SS apparatus consists of a membrane complex and an inner tail tube-like structure that is surrounded by a ...
Kai-Wei Yu, Peng Xue, Yang Fu, Liang Yang   +3 more
openaire   +2 more sources

Killing in the name of: T6SS structure and effector diversity

Microbiology, 2023
The life of bacteria is challenging, to endure bacteria employ a range of mechanisms to optimize their environment, including deploying the type VI secretion system (T6SS). Acting as a bacterial crossbow, this system delivers effectors responsible for subverting host cells, killing competitors and facilitating general secretion to access common goods ...
Luke P. Allsopp, Patricia Bernal
openaire   +6 more sources

Identification of A Putative T6SS Immunity Islet in Salmonella Typhi [PDF]

Pathogens, 2020
Typhoid fever is a major global health problem and is the result of systemic infections caused by the human-adapted bacterial pathogen Salmonella enterica serovar Typhi (S. Typhi). The pathology underlying S. Typhi infections significantly differ from infections caused by broad host range serovars of the same species, which are a common cause of ...
Luke Barretto, Casey Fowler
openaire   +3 more sources

Immunity proteins of dual nuclease T6SS effectors function as transcriptional repressors [PDF]

EMBO reports, 2021
Bacteria utilize type VI secretion system (T6SS) to deliver antibacterial toxins to target co-habiting bacteria. Here, we report that Burkholderia gladioli strain NGJ1 deploys certain T6SS effectors (TseTBg), having both DNase and RNase activities to kill target bacteria.
Sunil Kumar Yadav, Ankita Magotra, Srayan Ghosh, Aiswarya Krishnan, Amrita Pradhan, Rahul Kumar, Joyati Das, Mamta Sharma, Gopaljee Jha   +8 more
openaire   +2 more sources

Functional plasticity of antibacterial EndoU toxins. [PDF]

, 2018
Bacteria use several different secretion systems to deliver toxic EndoU ribonucleases into neighboring cells. Here, we present the first structure of a prokaryotic EndoU toxin in complex with its cognate immunity protein.
Eschenfeldt, William H, Goulding, Celia W, Hayes, Christopher S, Joachimiak, Andrzej, Jones, Allison M, Koskiniemi, Sanna, Low, David A, Michalska, Karolina, Nguyen, Josephine Y, Quan Nhan, Dinh, Stols, Lucy M, Willett, Julia LE   +11 more
core   +1 more source

Metabolic disharmony and sibling conflict mediated by T6SS

Microbial Cell, 2018
Bacteria in nature live in taxonomically complex communities where multitude of species and strains inhabit the same niches and compete for limited resources and space. Surviving in these competitive environments requires mechanisms to recognize and associate with kin and to discriminate against non-kin to increase reproductive success among close ...
Vera Troselj, Daniel Wall
openaire   +3 more sources

Type VI secretion: a beginner's guide [PDF]

, 2008
Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and ...
Akeda, Baron, Bladergroen, Brzuszkiewicz, Christopher M Bailey, Dandekar, Das, Das, de Bruin, Dreyfus, Dudley, Dudley, Durocher, Economou, Finn, Folkesson, Gardy, Henderson, Johnson, Kulasekara, Lewis EH Bingle, Mark J Pallen, Mougous, Mougous, Nano, Pallen, Parsons, Pukatzki, Pukatzki, Purcell, Roest, Schell, Schlieker, Seshadri, Shalom, Sheahan, Srinivasa Rao, Tatusov, VanRheenen, Ventre, Wang, Weibezahn, Williams, Yahr, Yeo, Zheng, Zheng, Zusman   +47 more
core   +1 more source

Genetic dissection of the type VI secretion system in Acinetobacter and identification of a novel peptidoglycan hydrolase, TagX, required for its biogenesis [PDF]

, 2016
The type VI secretion system (T6SS) is a widespread secretory apparatus produced by Gram-negative bacteria that has emerged as a potent mediator of antibacterial activity during interbacterial interactions.
Adams, Mark D, Ayala, Juan A, de Berardinis, Veronique, Feldman, Mario J, Foster, Leonard J, Hennon, Seth W, Scott, Nichollas E, Weber, Brent S, Wright, Meredith S   +8 more
core   +4 more sources

The Cronobacter genus: ubiquity and diversity [PDF]

, 2011
Members of the Cronobacter genus (formerly Enterobacter sakazakii) have become associated with neonatal infections and in particular contaminated reconstituted infant formula.
Baldwin, Bar-Oz, Bardowski, Barron, Beuchat, Biering, Block, Bowen, Brenner, Burdette, Carranza, Caubilla-Barron, Chap, Clark, Czerwicka, Eggers, Eva Kucerova, Farmer, Filloux, Friedemann, Gurtler, Harris, Healy, Henry, Himelright, Hurrell, Hurrell, Iversen, Iversen, Iversen, Iversen, Iversen, Iversen, Izard, Joseph, Kandhai, Kim, Kim, Kim, Kline, Kline, Kothary, Kucerova, Lai, Lehner, Lima-Mendez, Lucas, Maclean, Maclean, Maclean, Mittal, Mohan Nair, Mullane, Mullane, Muytjens, Muytjens, Muytjens, Muytjens, Nazarowec-White, Osaili, Pagotto, Pitout, Poirel, Richardson, Riedel, Sanders, Scheepe-Leberkuhne, Schmid, Simmons, Stephen Forsythe, Stock, Susan Joseph, Szafranek, Townsend, Townsend, Townsend, van Acker, Weir, Willis   +78 more
core   +1 more source

The Pseudomonas putida T6SS is a plant warden against phytopathogens [PDF]

The ISME Journal, 2017
Abstract Bacterial type VI secretion systems (T6SSs) are molecular weapons designed to deliver toxic effectors into prey cells. These nanomachines have an important role in inter-bacterial competition and provide advantages to T6SS active strains in polymicrobial environments.
Patricia Bernal, Luke P Allsopp, Alain Filloux, María A Llamas   +3 more
openaire   +5 more sources