Results 101 to 110 of about 25,344,545 (360)
The Journal of Poultry Science, 2013 The aim of this study was to determine how the mucosal immunity mediated by T cells is developed in the vagina. Antigen-presenting cells and T cells play important roles in the early process of host defense.
Takahiro Nii +2 more
doaj +1 more source
A mathematical model to study the impact of intra-tumour heterogeneity on anti-tumour CD8+ T cell immune response [PDF]
arXiv, 2021 Intra-tumour heterogeneity (ITH) has a strong impact on the efficacy of the immune response against solid tumours. The number of sub-populations of cancer cells expressing different antigens and the percentage of immunogenic cells (i.e. tumour cells that are effectively targeted by immune cells) in a tumour are both expressions of ITH. Here, we present
arxiv
Cell-by-cell deciphering of T cells in allergic inflammation [PDF]
Journal of Allergy and Clinical Immunology, 2019 Technical advances in single-cell RNA sequencing (scRNA-seq) render it possible to examine the transcriptomes of single cells in patients with allergic inflammation with high resolution in the context of their specific microenvironment, treatment, and disease status.
Ting Wen, Marc E. Rothenberg
openaire +2 more sources
FEBS Letters, EarlyView.LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra +7 more
wiley +1 more source
T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development
Cell Reports, 2020 Summary: T cell factor 1 (Tcf1) promotes the central memory CD8+ T (TCM) cell differentiation and stemness in lymphoid tissues after systemic infections.
Jingxia Wu +10 more
doaj
Confirmation that T cell receptor activation is digital, not analog. Hence individual T cell cytolytic capacity is independent of initial stimulation strength [PDF]
arXiv, 2018 Whether a sub-optimum lymphocyte stimulus is achieved by lowering ligand concentration, or decreasing its affinity, initial TCR activation responses are likely to be digital. We now know for cultured peripheral blood mononuclear cells (PBMCs), when activated by plant lectins such as concanavalin-A (Con-A), that the responding cells are T cells, and ...
arxiv
Cell–cell and cell–matrix interactions
Molecular Biology of the Cell, 2013 In this year's annual ASCB Meeting Minisymposium on Cell–Cell and Cell–Matrix Interactions, new data were presented on several aspects of the biology of cell adhesions. The role of cell adhesions in cancer was the topic of three of the talks, two of which were focused on identifying how invasion is affected by cell–matrix and cell–cell adhesions ...
openaire +2 more sources
The cell secretome, a mediator of cell-to-cell communication [PDF]
Prostaglandins & Other Lipid Mediators, 2015 We are witnessing the emergence of a novel type of biological regulation, namely, the communication between cells via their secreted substances, the secretome. This brief overview is based on the available published data and our own experience. We discuss three vignettes illustrating the importance of communication via the secretome: (1) the secretome ...
Joseph Zullo +4 more
openaire +3 more sources
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Molecular Genetics of T Cell Development [PDF]
, 2005 T cell development is guided by a complex set of transcription factors that act recursively, in different combinations, at each of the developmental choice points from T-lineage specification to peripheral T cell specialization. This review describes the
Aifantis I +27 more
core +1 more source