Results 101 to 110 of about 28,819,884 (406)

Immunological Changes after Cancer Treatment and Participation in an Exercise Program [PDF]

open access: yes, 2003
Purpose: The purpose of this investigation was to evaluate the impact of undertaking peripheral blood stem cell transplantation (PBST) on T-cell number and function, and to determine the role of a mixed type, moderate intensity exercise program in ...
Andrykowski   +27 more
core   +2 more sources

The interplay of cell–cell and cell–substrate adhesion in collective cell migration [PDF]

open access: yesJournal of The Royal Society Interface, 2014
Collective cell migration often involves notable cell–cell and cell–substrate adhesions and highly coordinated motion of touching cells. We focus on the interplay between cell–substrate adhesion and cell–cell adhesion. We show that the loss of cell-surface contact does not significantly alter the dynamic pattern of protrusions and ...
Chenlu, Wang   +5 more
openaire   +2 more sources

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

T cell-intrinsic role of IL-6 signaling in primary and memory responses

open access: yeseLife, 2014
Innate immune recognition is critical for the induction of adaptive immune responses; however the underlying mechanisms remain incompletely understood.
Simone A Nish   +14 more
doaj   +1 more source

Oestrogen, an evolutionary conserved regulator of T cell differentiation and immune tolerance in jawed vertebrates? [PDF]

open access: yes, 2018
In teleosts, as in mammals, the immune system is tightly regulated by sexual steroid hormones, such as oestrogens. We investigated the effects of 17β-oestradiol on the expression of several genes related to T cell development and resulting T cell ...
Duflot, Aurélie   +5 more
core   +2 more sources

T Cell Dysfunction and Exhaustion in Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2020
Tumor immunotherapy is a promising therapeutic strategy for patients with advanced cancers. T cells are key mediators of antitumor function that specifically recognize and react to tumor-expressing antigens and have proven critical for cancer ...
Zhen Zhang   +5 more
semanticscholar   +1 more source

Cell Simulation as Cell Segmentation

open access: yesNature Methods
AbstractSingle-cell spatial transcriptomics promises a highly detailed view of a cell’s transcriptional state and microenvironment, yet inaccurate cell segmentation can render this data murky by misattributing large numbers of transcripts to nearby cells or conjuring nonexistent cells.
Daniel C. Jones   +5 more
openaire   +3 more sources

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Cell Stress and Cell Death

open access: yesInternational Journal of Cell Biology, 2010
This special issue on Cell Stress and Cell Death is aimed at bringing together recent developments in the fields of cellular stress and cell death and, in particular, the interplay between cell stress responses and cell death. The special issue opens with a review by S. Fulda et al.
Afshin Samali   +4 more
openaire   +5 more sources

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

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